Emerging Problem Evaluation of Hypocalcemia in Super Vasmol Hair Dye Poisoning Patients: Clinical Study in RIMS, Kadapa
Abstract
Introduction: One of the most frequent method of suicide attempt in India is intentional super vasmol poisoning. If it is untreated, it leads to many complications such as, rhabdomyolysis, angioedema, acute kidney injury, and hypocalcemia. Of all above mentioned; hypocalcemia can cause pathologies of the neuromuscular, cardiovascular, and respiratory systems. Early detection and treatment of the issue can reduce the diseases and fatalities that are related to it.
Aim: This study aims to assess the incidence, clinical manifestations, and management of hypocalcemia in super vasmol poisoning patients.
Methods: A prospective observational study was undertaken on 50 super vasmol poisoning patients for about six months at the government general hospital, RIMS, Kadapa from November 2021 to April 2022. Only subjects who are willing to give their consent were included in the study. All trial participants were observed for the duration of their hospital stay to evaluate hypocalcemia.
Results: Out of the 50 subjects, 22 (44%) were male, 28 (56%) were female, and the majority (40%) were in between the age group of 21 to 30 years. 15 patients (30%) out of the 50 subjects were developed with hypocalcemia, particularly those who consumed more than 50 ml of super vasmol. We observed that 66.5% of subjects received parenteral calcium gluconate while 33.5% subjects received oral calcium carbonate.
Conclusion: Hypocalcemia is a hidden complication of super vasmol poisoning, and there is a need to raise awareness among the among medical professionals about the necessity of routinely checking serum calcium levels as well as public regarding the dangers of super vasmol.
Keywords: Super vasmol, Toxicity, Hypocalcemia, Hospitalization, Counselling.
Keywords:
Super vasmol,, Toxicity,, Hypocalcemia,, Hospitalization,, Counselling.DOI
https://doi.org/10.22270/jddt.v13i7.6116References
Kondle R, Pathapati, RM, Saginela SK, Malliboina S, Makineedi VP. Clinical Profile and Outcomes of Hair Dye Poisoning in a Teaching Hospital in Nellore. ISRN Emerg Med. 2012:1–5. https://doi.org/10.5402/2012/62425 .
Garg SK, Tiwari R, Ahlawat A. Hair dye poisoning: An unusual encounter. Indian J Crit Care Med. 2014 Jun; 18(6):402-4. doi: https://doi.org/10.4103/0972-5229.133941 .
Chaudhari, Vinod & Kumaran, M. & Mittal, Chaitanya & Srinivas, Bheemanathi & Shaha, Kusa. Hair Dye Poisoning and Toxic effects of Paraphenylenediamine. Journal of the Indian Society of Toxicology. 2017; 13:37-40.
Bhagavathula AS, Bandari DK, Khan M, Shehab A. A systematic review and meta-analysis of the prevalence and complications of paraphenylenediamine-containing hair dye poisoning in developing countries. Indian J Pharmacol. 2019; 51(5):302-15. doi: https://doi.org/10.4103/ijp.IJP_246_17 .
Nirmala MS, Ganesh R. Hair dye- an emerging suicidal agent: Our experience. Otolaryngology online journal. 2012; 2(2):1-11.
Sakuntala P, Musa Khan P, Sudarsi B, Manohar S, Siddeswari R, Swaroop K. Clinical Profile and Complications of Hair Dye Poisoning. Int J Sci Res Publ. 2014; 5(6):1-4.
Asghar S, Mahbub S, Asghar S, Shahid S. Paraphenylenediamine (Hair Dye) Poisoning: A Prospective Study on the Clinical Outcome and Side Effects Profile. Cureus. 2022; 14(9):e29133. doi: https://doi.org/10.7759/cureus.29133 .
Senthilkumaran S, Jena NN, Thirumalaikolundusubramanian P. Super Vasmol Poisoning: Dangers of Darker Shade. Indian J Crit Care Med. 2019; 23(Suppl 4):S287-S289. doi: https://doi.org/10.5005/jp-journals-10071-23303 .
Khaskheli MS, Shaikh S, Meraj M, Raza H, Aslam I. Paraphenylenediamine poisoning: clinical features, complications and outcome in a tertiary care. Anaesth Pain & Intensive Care. 2018; 22(3):343-7.
Fong J, Khan A. Hypocalcemia: Updates in diagnosis and management for primary care. Can Fam Physician. 2012; 58(2):158-62. PMID: 22439169.
Prabhakar M. Supervasmol33 Keshkala Poisoning: Role of ENT Surgoen. Indian J Otolaryngol Head Neck Surg. 2014; 66(Suppl 1):281-5. doi: https://doi.org/10.1007/s12070-012-0488-7 .
Zhang MH. Rhabdomyolosis and its pathogenesis. World J Emerg Med. 2012; 3(1):11-5. doi: 10.5847/wjem.j.issn.1920-8642.2012.01.002. PMID: 25215032. https://doi.org/10.5847/wjem.j.issn.1920-8642.2012.01.002
Schafer AL, Shoback DM, Feingold KR, Anawalt B, Blackman MR, BoyceA. Hypocalcemia: Diagnosis and Treatment. 2016; Endotext [Internet]. South Dartmouth (MA): MDText.com, PMID: 25905251.
Aul AJ, Fischer PR, O'Grady JS, Mara KC, Maxson JA, Meek AM. Population-Based Incidence of Potentially Life-Threatening Complications of Hypocalcemia and Role of Vitamin D Deficiency. J Pediatr. 2019; 211:98-104. PMID: 30954245 . https://doi.org/10.1016/j.jpeds.2019.02.018
Varun Kumar V, Sureswara Reddy M, Leela Prased K. A Prospective Study on Clinical Manifestations and Consequences of Super Vasmol Poisoning In a Tertiary Care Hospitalin Kadapa. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS). 2020; 19 (4): 12-6.
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