High concentration Amiodarone continuous infusion induced Phlebitis: A Case Report
Abstract
Phlebitis caused by high concentration amiodarone infusion is a rather uncommon occurrence. Phlebitis is one of the most reported causes of high concentration amiodarone continuous infusion in bradycardia. We reported a case of patient with continuous infusion of amiodarone induced phlebitis. Patient felt pain along the path of cannula, erythema, induration, palpable venous cord. Visual Infusion Phlebitis Score was assessed and VIP Score was found to be 4. We suspected the incidence of phlebitis due to high concentration and continuous infusion of IV amiodarone. In this case report, we would like to discuss about the standard protocol of IV administration of amiodarone, evaluation of phlebitis by Visual Infusion Phlebitis Score, and management of Phlebitis.
Keywords: Visual Infusion Phlebitis Score, amiodarone, phlebitis, tachyarrhythmia, peripheral administration.
Keywords:
Visual Infusion Phlebitis Score, amiodarone, phlebitis, tachyarrhythmia, peripheral administrationDOI
https://doi.org/10.22270/jddt.v13i6.6091References
Vassallo P, Trohman RG. Prescribing amiodarone: evidence-based review of clinical indications. JAMA. 2007; 298(11): 1312-1322. https://doi.org/10.1001/jama.298.11.1312
Hilleman DE, Hansen JM, Mohiuddin SM. Amiodarone-induced infusion phlebitis. Clin Pharm. 1987; 6:364-367.
Jeffrey B. Florek. Amiodarone - StatPearls - NCBI Bookshelf. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482154/
Gazitua, R., Wilson, K., Bistrian, B. R., & Blackburn, G. L. Factors determining peripheral vein tolerance to amino acid infusions. Archives of Surgery 1979; 114:897-900. https://doi.org/10.1001/archsurg.1979.01370320029005
Boyce BA, Yee BH. Incidence and severity of phlebitis in patients receiving peripherally infused amiodarone. Crit Care Nurse. 2012; 32:27-34. https://doi.org/10.4037/ccn2012139
Dixon HA, Hort AL, Wright CM. Amiodarone-induced phlebitis remains an issue in spite of measures to reduce its occurrence. J Vasc Access. 2019; 20:786-7. https://doi.org/10.1177/1129729819838123
Hannibal GB. Peripheral phlebitis related to amiodarone infusion. AACN A dv Crit Care. 2016; 27:465-71. https://doi.org/10.4037/aacnacc2016249
Norton L, Ottoboni LK, Varady A, Yang-Lu C-Y, Becker N, Cotter T, et al. Phlebitis in amiodarone administration: Incidence, contributing factors, and clinical implications. American Journal of Critical Care. 2013; 22(6):498-505. https://doi.org/10.4037/ajcc2013460
Cordarone IV (amiodarone intravenous): Uses, dosage, side effects, interactions, warning [Internet]. RxList. RxList; 2021.Available from: https://www.rxlist.com/cordarone-iv-drug.htm
Brørs, G. et al. (2023) "Amiodarone-induced phlebitis: Incidence and adherence to a clinical practice guideline," European Journal of Cardiovascular Nursing [Preprint]. https://doi.org/10.1093/eurjcn/zvad003
Oragano, C.A., Patton, D. and Moore, Z. "Phlebitis in intravenous amiodarone administration: Incidence and contributing factors," Critical Care Nurse, 2019; 39(1). https://doi.org/10.4037/ccn2019381
Dixon, H.A., Hort, A.L. and Wright, C.M. "Amiodarone-induced phlebitis remains an issue in spite of measures to reduce its occurrence," The Journal of Vascular Access, 2019; 20(6):786-787. https://doi.org/10.1177/1129729819838123
"The Bangkok Medical Journal" (no date). https://doi.org/10.31524/bkkmedj
Cottrill, K.N. "Implementation of an amiodarone infusion nurse practice guideline to reduce the incidence of phlebitis: A quality improvement project." https://doi.org/10.33915/etd.11631
CORDARONE(R) intravenous, amiodarone HCl intravenous. Wyeth Pharmaceuticals Inc., Philadelphia, PA, 2005.
Amiodarone HCl intravenous injection, amiodarone HCl intravenous injection. Teva Canada Limited (per Health Canada), Toronto, ON, Canada, 2016.
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