To investigate phytochemical parameter, Pharmacognostical evaluation, pharmacological (anti-bacterial) activity of the extract of Euphorbia pulcherrima
Abstract
Introduction: Euphorbia pulcherrima is member of Euphorbiaceae family of medicinal plants, and it is used to cure variety of ailments which includes toothache, vomiting, fractures, severe bleeding, bruising, and hypermenorrhoea. Euphorbia pulcherrima has been found to possess a variety of chemicals, including alkaloids, steroids, terpenoids, flavonoids and reducing sugars. The review analyses its pharmacological profile, chemical component, and phytochemistry, with an emphasis on antioxidant activity, antimicrobial activity, Osteoclast activity, analgesic activity, anti-inflammatory activity, sedative activity, muscle relaxant activity, anticonvulsant activity and toxicological profile, in order to better assess the plants medicinal potential. Traditionally the latex has been employed as an anti-vomiting and toothache treatment. Aches and pains have been treated with leaf poultices. In traditional Chinese medicine it has been used it to treat fractures, severe bleeding, bruising, and hypermenorrhoea.
Methods: Due to extensive research on the pharmacological effects and active compounds of Euphorbia pulcherrima, it has a great deal of potential in modern medicine. Phyto, physicochemical standardization of dried, matured root of Euphorbia pulcherrima has been carried out in the present study. The study includes organoleptic characters along with estimation of its physicochemical parameters such as loss on drying, ash values, extractability in water and methanol. Preliminary phytochemical screening and anti-bacterial assay has been conducted.
Conclusion: As there is not enough evidence for detailed physicochemical and phytochemical evaluation on root of Euphorbia pulcherrima is reported. The present study reveals that the selected plant extract produces antimicrobial activity with dose dependent manner. However, it needs further evaluation in clinical settings before consideration for the treatment of different diseases.
Keywords: Euphorbia pulcherrima, Phytochemicals, pharmacological activity, Physicochemical.
Keywords:
Euphorbia pulcherrima, Phytochemicals, pharmacological activity, PhysicochemicalDOI
https://doi.org/10.22270/jddt.v13i8.5931References
Rauf A, Mohammad N. Phytochemical and pharmacological evaluation of aerial parts of Euphorbia pulcherrima L. WudpecherJornal of Pharmacy and Pharmacology. 2013; 2(2):15-20.)
Yakubu AI, Mukhtar MD. In vitro antimicrobial activity of some phytochemical fractions of Euphorbia pulcherimaL. (Poinsettia). Journal of medicinal plants research. 2011 Jun 18; 5(12):2470-5.)
Dai Y, Liu S, Xu J, Zhao C, Gu Q. Triterpenoids from Euphorbia pulcherrima with inhibitory effects on osteoclastogenesis. Fitoterapia. 2019 Apr 1; 134:355-61. https://doi.org/10.1016/j.fitote.2019.02.028
Kurian JC. Plants that heal. Pune, India: Oriental Watchman Publishing House; 1995. p. 134-56
Siddiqui & M.A. Hakim, Format for the pharmacopoeial analytical standards of compound formulation, workshop on standardization of Unani drugs, anuary, Central Council for Research in Unani Medicine (CCRUM), New Delhi, (appendix), 1995, 24-25
Shewale S, Undale V, Shelar M, Pimple B, Kuchekar M, Bhalchim V. Macroscopic and Microscopic Evaluation of Sansevieria cylindrica Plant. Pharmacognosy Research. 2022; 14(4). https://doi.org/10.5530/pres.14.4.60
Anbazhahi T., Kadavul K., Suguna G., Petrus A.J.A. Studies on the pharmacognostical and in vitro antioxidant potential of Cleome gynandra Linn. Leaves. Nat Prod Radiance. 2009; 8(2):151-7)
Gupta P, Vasudeva N, and Sharma S.K. Pharmacognostical Study and Preliminary Phytochemical Screening of the Roots of Tagetes erecta Linn. Roots. Hamdard Medicus 2009; 52(1).
World Health Organization. organization mondiale De La santé, Quality control methods for plant materials, 559. Rev.; 1:08-67.
Choudhary N, Sekhon BS, An overview of advances in the standardization of herbal drugs, J. Pharm Educ. Res., 2011; 2(2):55-70.
Kokate CK, Khandelwal KR, Pawer AP, Gokhale SB, Practical Pharmacognosy, 3rd edition, Nirali Prakashan, Pune, 1995, 137
Farnsworth NR, Biological and Phytochemical screening of Plants, Journal of pharmaceutical Science, 1996; 55:225-276 https://doi.org/10.1002/jps.2600550302
Tolulope O. Phytochemical Screening, Antibacterial Activity and Fatty Acids from Heliotropium Indicum. Pharmacognosy Journal. 2023; 15(2). https://doi.org/10.5530/pj.2023.15.53
Tofighi Z, Molazem M, Doostdar B, Taban P, Shahverdi AR, Samadi N, Yassa N. Antimicrobial activities of three medicinal plants and investigation of flavonoids of Tripleurospermum disciforme. Iranian journal of pharmaceutical research: IJPR. 2015; 14(1):225
Published
Abstract Display: 629 
PDF Downloads: 774 PDF Downloads: 88 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.