The Potentials of Herbal Plant against the Psoriasis

  • Jayshree B Sanap Gawande college of Pharmacy, Sakharkherda, Tq. Sindhkhed Raja Dist. Buldana (MH)
  • Anil V. Chandewar Pataldhamal Wadhwani college of Pharmacy, Yavatmal
  • Nitin Kochar Pataldhamal Wadhwani college of Pharmacy, Yavatmal
  • Shatrughna Uttam Nagrik Satyajeet College of Pharmacy, Khandala Mehkar, Buldana (MH)

Abstract

Chronic autoimmune skin disease termed psoriasis is characterised by excessive keratinocyte multiplication, scaly plaques, severe inflammation, and erythema. T lymphocytes, leukocytes, vascular endothelium, and epidermal keratinocytes also contribute in the pathogenesis of psoriasis. Increased leukocyte recruitment and increased levels of cytokines, growth factors, and genetic factors like interleukin (IL)-1, IL-6, IL-17, IL-22, IL-23, tumour necrosis factor (TNF), interferon (IFN), transforming growth factor (TGF), toll-like receptor (TLR)-2, signal transducer and activator of transcription (STAT-3), 15-lipoxygenase (LOX)-2. The most important aspects impacting the treatment of psoriasis are coiled-coil alpha-helical rod protein 1 (CCHCR1), steroidogenic acute regulatory protein (StAR), and vitamin D receptor (VDR). Various synthetic medicinal drugs have also been known to have the side effect of psoriasis. Due to their safety and accessibility, herbal medications may indicate the potential as effective anti-psoriatic agents.


Keywords: Psoriasis, Herbal Drug, Silybum marianum, Thespesia populnea, Mahonia aquifolium

Keywords: Psoriasis, Herbal Drug, Silybum marianum, Thespesia populnea, Mahonia aquifolium

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Author Biographies

Jayshree B Sanap, Gawande college of Pharmacy, Sakharkherda, Tq. Sindhkhed Raja Dist. Buldana (MH)

Gawande college of Pharmacy, Sakharkherda, Tq. Sindhkhed Raja Dist. Buldana (MH)

Anil V. Chandewar, Pataldhamal Wadhwani college of Pharmacy, Yavatmal

Pataldhamal Wadhwani college of Pharmacy, Yavatmal

Nitin Kochar, Pataldhamal Wadhwani college of Pharmacy, Yavatmal

Pataldhamal Wadhwani college of Pharmacy, Yavatmal

Shatrughna Uttam Nagrik, Satyajeet College of Pharmacy, Khandala Mehkar, Buldana (MH)

Satyajeet College of Pharmacy, Khandala Mehkar, Buldana (MH)

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Sanap J, Chandewar A, Kochar N, Nagrik S. The Potentials of Herbal Plant against the Psoriasis. JDDT [Internet]. 15Jan.2023 [cited 27Jan.2023];13(1):179-82. Available from: https://jddtonline.info/index.php/jddt/article/view/5903