Assessment of resilience of aromatic plants during the COVID-19 pandemic in Douala, Cameroon

Authors

  • Patrice Brice Brice Mvogo Ottou Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon
  • Christian Wilson Saagu Fogang Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon
  • Zenabou Ndiang Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon
  • Jacques Bruno Ngotta Biyon Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon
  • Seraphine Ebenye Mokake Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon
  • Fidèle Bemadoum Mbezo Laboratory of Microbiology, Faculty of Science, University of Yaoundé I, PO Box. 812 Yaoundé, Cameroon
  • Jean Lagarde Betti Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon
  • Din Ndongo Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon
  • Richard Jules Priso Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Abstract

Aromatic plants are one of the components of Cameroonian medicinal flora that seem to be an alternative to fight against the Covid-19 disease. The present study aims to establish chemical characterization of some aromatic plant organs used in the Douala IV sub-division during the COVID-19 pandemic. A semi-structured survey was carried out between September and December 2020 in order to identify aromatic plants used for health diseases during the Covid-19 pandemic. Due to their ethnobotanical index the selected plants were screened chemically through staining and precipitation methods to determine different bioactive compounds. Thirty-one (31) plant species belonging to 17 families were recorded with the dominated by Lamiaceae and Zingiberaceae being the dominant families and Ocimum gratissimum as the most cited species (28.57%) in the composition of recipes. Leaves (50.80%) were the most used organs to prepare the decoctions (33.33%) administered to patients orally. These plants were used in the treatment of 51 ailments diseases, notably malaria, cough and typhoid fever with 22, 21 and 12 citations respectively. Informant Consensus Factors (ICF) showed a relatively high agreement (0.75) for the use of species against respiratory diseases. Zingiber officinale, Citrus limon and Cymbopogon citratus had a good performance (Ip = 3) against cough, typhoid and malaria respectively. Extracts of aromatic plant organs were rich in alkaloids and phenolic compounds. These aromatic species showed their ability to treat respiratory and other infectious diseases, and could be an alternative to fight against Covid-19.

Keywords: Aromatic plants; Bioactive compounds; Douala IV; Drug recipes; Ethnobotanical index.

Keywords:

Aromatic plants, Bioactive compounds, Douala IV, Drug recipes, Ethnobotanical index

DOI

https://doi.org/10.22270/jddt.v12i5.5580

Author Biographies

Patrice Brice Brice Mvogo Ottou, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Christian Wilson Saagu Fogang, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Zenabou Ndiang, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Jacques Bruno Ngotta Biyon, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Seraphine Ebenye Mokake, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Fidèle Bemadoum Mbezo, Laboratory of Microbiology, Faculty of Science, University of Yaoundé I, PO Box. 812 Yaoundé, Cameroon

Laboratory of Microbiology, Faculty of Science, University of Yaoundé I, PO Box. 812 Yaoundé, Cameroon

Jean Lagarde Betti, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Cameroon National Herbarium, PO Box. 812 Yaoundé, Cameroon

Din Ndongo, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Richard Jules Priso, Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

Biology and Physiology Laboratory of Plant Sciences, Faculty of Sciences, University of Douala, PO Box. 24157 Douala, Cameroon

References

Betti JL, "Rapport sur Stratégie/Plan d'action pour une meilleure collecte des données Statistiques sur les PFNLs au Cameroun et recommandations pour les pays de la COMIFAC" 2007.

Koné Kamanzi A, "Inventaire ethnomédical et évaluation de l'activité antihelminthique des plantes médicinales utilisées en Côte d'Ivoire contre les helminthiases intestinales" Pharm. Méd. Trad. Afr., 2006; 14 :55-72.

Priso RJ, Nnanga JF, Etame J, Din N, Amougou A, "Les produits forestiers non ligneux d'origine végétale : valeur et importance dans quelques marchés de la région du littoral-Cameroun" J. Appl. Biosci., 2011; 40:2715-2726.

Jiofack T, Fokunang C, Guedje N, Kemeuze V, Fongnzossie E, Nkongmeneck BA, Mapongmetsem PM, Tsabang N, "Ethnobotanical uses of medicinal plants of two ethnoecological regions Cameroon" International Journal of Medicine and Medical Sciences, 2010 ; 2:60-79. http://www.acade mic jo urna ls.org/ijmms

Fokouo Fogha JV, Noubiap JJ, "La lutte contre le COVID-19 au Cameroun nécessite un second souffle" Pan African Medical Journal, 2020; 37:14 p. https://doi.org/10.11604/pamj.supp.2020.37.1.23535

Kuete-Sezine C, Banen JB, Foka-nkwenti C, Bedziga Bedziga S, Nguendo-yongsi HB, "Médecine traditionnelle et lutte contre la covid-19 au Camerounc" International Journal of Science Academic Research, 2021; 02:1051-1057.

Neffati M, Sghaier M, "Développement et valorisation des plantes aromatiques et médicinales (PAM) au niveau des zones désertiques de la région MENA (Algérie, Egypte, Jordanie, Maroc et Tunisie) " Rapport principal du Projet MENA-DELP : Partage des connaissances et de coordination sur les écosystèmes désertiques et les moyens de subsistance au profit de l'Algérie, l'Egypte, la Jordanie, le Maroc et la Tunisie" 2014 ; 143 p.

Ngoule C, Ngene J, Kidik P, Dibong S, Ndjib R, "Inventaire et caractérisation floristique des plantes médicinales à huiles essentielles des marchés de Douala Est"International journal of chemical sciences, 2015 ; 9:874-889. https://doi.org/10.4314/ijbcs.v9i2.26

Agbor Agbor G, Ndjib RC, "Systematic Review of Plants Used Against Respiratory Diseases Related to Covid-19 in Africa" Journal of Drug Delivery and Therapeutics, 2021; 11:1-14. https://doi.org/10.22270/jddt.v11i4-S.4957

Abdou Bouba A, Njintang YN, Scher J, Mbofung CMF, "Phenolic compounds and radical scavenging potential of twenty Cameroonian spices" Agric. Biol. J. N. Am., 2010; 1:213-224. https://doi.org/10.5251/abjna.2010.1.3.213.224

Belakhdar J, "Plantes médicinales au Maghreb et soins de base, Précis de phytothérapie moderne" Editions Le Fennec, Casablanca-Maroc, 2006 ; 386 p.

Betti JL, Lejoly J, "Les plantes indiquées comme antihelminthiques en thérapie traditionnelle dans la réserve de biosphère du Dja (Cameroun)" Revue Soma, 2010; 4-16 2 3:60-79. https://doi.org/10.4314/ijbcs.v4i1.54246

Adjanohoun E, Aboubakar N, Dramane K, Sofowora A, Tamze V, Ebot E, Ekpere A, Kamanyi A, Kamsu J, Keita A, "Contribution to ethnobotanical and foristic studies in Cameroon" CSTR/OUA, Cameroon, 1996.

Hoffman B, Gallaher T, "Indice d'importance en ethnobotanique" Ethnobotanique Recherche et applications 2007; 5:201-218. https://doi.org/10.17348/era.5.0.201-218

Dassou HG, Ogni CA, Yedomonhan H, Adomou AC, Tossou M, Dougnon JT, Akoegninou A, "Diversité, usages vétérinaires et vulnérabilité des plantes médicinales au Nord-Bénin Int. J. Biol. Chem. Sci., 2014; 8:189-210.

https://doi.org/10.4314/ijbcs.v8i1.18

Andrade-cetto A, Heinrich M, "Des approches utiles pour sélectionner des espèces en fonction des connaissances locales" Frontières en pharmacologie, 2011; 2:1-5.

Ilumbe GB, Van Damme P, Lukoki FL, Joiris V, Visser M, Lejoly J, "Contribution à l'étude des plantes médicinales dans le traitement des hémorroïdes par les pygmées Twa et leur voisin Oto de Bikoro, en RDC" Congo Sciences, 2014; 2:46 - 54.

Ugulu I, "L'enquête et l'évaluation ethnobotanique quantitative des plantes médicinales utilisées autour de la province d'Izmir, Turquie. Journal de recherche sur les plantes médicinales" 2009; 3:345-367.

Sumitra C, Jigna P, Nehal K, "Evaluation of antibacterial activity and phytochemical analysis of Bauhinia variegate L. bark" Afr. J. Biomed. Res., 2006; 9 :53-56.

Mangambou D, Mushagalusa KF, Kadima N, "Contribution à l'étude phytochimique de quelques plantes médicinales antidiabétiques de la ville de Bukavu et ses environs (Sud- Kivu, RD Congo) " Journal of Applied Biosciences, 2014; 75:6211-6220. https://doi.org/10.4314/jab.v75i1.7

Kidik Pouka MC, Ngene JP, Ngoule CC, Mvogo Ottou PB, Ndjib RC, Dibong SD, Mpondo Mpondo E, "Caractérisation des plantes médicinales à flavonoïdes des marchés de Douala (Cameroun) " Int. J. Biol. Chem. Sci., 201 ; 9:1494-1516. https://doi.org/10.4314/ijbcs.v9i3.32

Fathia A, Abderrahman B, Mohamed A, "Etude ethnobotanique des plantes médicinales de la région de |Tanger. Cas de Hjar nhal et Melloussa" Int. J. Adv. Res., 2017; 5:310-322. https://doi.org/10.21474/IJAR01/5772

Dibong SD, Mvogo Ottou PB, Vandi D, Ndjib RC, Monkam Tchamaha F, Mpondo Mpondo E, "Ethnobotanique des plantes médicinales anti hémorroïdaires des marchés et villages du Centre et du Littoral Cameroun" Journal of Applied Biosciences 2015; 96:9072-9093. https://doi.org/10.4314/jab.v96i1.5

Mvogo Ottou PB, Etame Loe GM, Ngotta Biyon JB, Ebenye Mokake S, Bissemb OP, Owono Fouda LR, Ngouondjou Foze T, Priso RJ, Dibong SD, "Knowledge of tradi-practitioners on hemorrhoidal disease and anti-hemmoroidal plants in the southeast region of Cameroon: pharmacology and preliminary phytochemistry" Saudi Journal of Medical and Pharmaceutical Sciences, 2020; 6:321-333. https://doi.org/10.36348/sjmps.2020.v06i04.001

Mpondo Mpondo E, Vandi D, Ngouondjou Foze T, Mvogo Ottou PB, Embolo EE, Dibong SD, "Contribution des populations des villages du centre Cameroun au traitement traditionnel des affections des voies respiratoires" Journal of Animal &Plant Sciences 2017; 32:5223-5242.

Tchiégang C, Mbougueng PD, "Composition chimique des épices utilisées dans la préparation du Nah poh et du Nkui de l'ouest Cameroun" Tropicultura, 2005; 23:193-200.

Abdou Bouba A, "Contribution à l'étude du développement d'un aliment fonctionnel à base d'épices du Cameroun : caractérisation physico-chimique et fonctionnelle" Thèse de Doctorat, Université de Ngaoundéré, Cameroun, 2009 ; 223 p.

Filiat P, "Les plantes de la famille des Apiacées dans les troubles digestifs" Thèse de doctorat en pharmacie, Université de Joseph Fourier, Grenoble, 2012 ; 140 p.

Mpondo Mpondo E, Dibong SD, Ladoh YCF, Priso RJ, Ngoye A, "Les plantes à phénols utilisées par les populations de la ville de Douala" Journal of Animal and Plant Sciences, 2012; 15:2083-2098.

Vandi D, Nnanga Nga E, Betti JL, Etame Loe GM, Mvogo Ottou PB, Priso RJ, Ngouondjou Foze T, Ngo Boumsong PC, Dibong SD, Mpondo Mpondo, "Contribution des populations des villes de Yaoundé et Douala à la connaissance des plantes à tanins et à anthocyanes" Journal of Animal & Plant Sciences, 2016; 3:4797-4814.

Sereme A, Millogo-Rasolodimby J, Guinko S, Nacro M, "Anatomie et concentration des tanins des plantes tannifères du Burkina Faso" Journal des Sciences, 2010; 2:24 - 32.

Ngene J, Ngoule C, Mvogo O, Mpondo E, Dibong S, "Importance dans la pharmacopée des plantes à flavonoides vendues dans les marches de Douala Est (Cameroun) " Journal of Applied Biosciences, 2015; 88:8194-8219. https://doi.org/10.4314/jab.v88i1.6

Lahsissene H, Kahouadji A, Tijane M, Hseini S, "Catalogue des plantes médicinales utilisées dans la région de Zaër (Maroc occidental)" Lejeunia BE ISSN, 2009; 0457-4184.

Salhi S, Fadli M, Zidane L, Douira A, "Etudes floristique et ethnobotanique des plantes médicinales de la ville de Kénitra (Maroc) " Lazaroa, 2010; 31:133-146. https://doi.org/10.5209/rev_LAZA.2010.v31.9

Ilumbe GB, "Utilisation des plantes en médecine traditionnelle par les Pygmées (Ba-twa) et les Bantous (Ba-Oto) du territoire de Bikoro, province de l'Equateur en RD Congo" Thèse Doct. Univ. Libre de Bruxelles, 2010 ; 237p.

Sartoratto A, Machado ALM, Delarmelina C, Figueira GM, Duarte MCT, Rehder VLG, "Composition and antimicrobial activity of essential oils from aromatic plants used in Brazil" Brazilian Journal of Microbiology, 2004; 35:275-280. https://doi.org/10.1590/S1517-83822004000300001

Sessou P, Souaïbou F, Guy A, Sébastien DT, Boniface Y, Paulin A, "Chemical Composition and Antifungal activity of Essential oil of Fresh leaves of Ocimum gratissimum from Benin against six Mycotoxigenic Fungi isolated from traditional cheese wagashi" I. Res. J. Biological Sci., 2012; 1:22-27.

Bruneton J, "Pharmacognosie, phytochimie, des plantes médicinales 4e édition" Ed. Tec & Doc, Paris, 2009; 1269p.

Oyono V, Fokunang C, Tembe-Fokunang E, Tsague M, Messi A, Assam J, Ngameni B, Kechia F, Nwabo Kamdje AH, Penlap V, Ngadjui B, "Phytochemical screening and biological cctivity studies of the extract from the bark of Ricinodendron heudoletti, Euphorbiaceae" Journal of Diseases and Medicinal Plants, 2016; 2:83-89. https://doi.org/10.11648/j.jdmp.20160206.14

Fongnzossie Fedoung E, Biwole, Nyangono Biyegue CF, Ngansop M, Akono Ntonga P, Essono DM, Funwi FP, Tonga C, Nguenang GM, Kemeuze VA, Sonwa DJ, Nole Tsabang, Bouelet IS, Tize Z, Boum AT, Momo Solefack MC, Betti JL, Nouga Bissoue A, Lehman LG, Mapongmetsem PM, Ngono Ngane A, Ngogang Yonkeu J, "Searching nature-based solutions to emerging diseases: a preliminary review of cameroonian medicinal plants with potentials for the management of COVID-19 pandemic" Systematic Review 2020 ; 3-56. https://doi.org/10.21203/rs.3.rs-100548/v1

Adem S, Eyupoglu V, Sarfraz I, Rasul A, Ali M, "Identification of Potent COVID-19 Main Protease (Mpro) Inhibitors from Natural Polyphenols: An in Silico Strategy Unveils a Hope against Corona" Preprints 2020; DOI: 10.20944/preprints202003.0333.v1.Available from:https://www.researchgate.net/publication/340095736_Identification_of_Potent_COVID19_Main_Protease_Mpro_Inhibitors_from_Natural_Polyphenols_An_in_Silico-trategy_Unveis_a_Hope_against_CORONA [accessed Apr 21 2020]. https://doi.org/10.20944/preprints202003.0333.v1

Mohammadi N, Shaghaghi N, "Inhibitory Effect of Eight Secondary Metabolites from Conventional Medicinal Plants on COVID-19 Virus Protease by Molecular Docking Analysis" ChemRxiv. Preprint, 2020; https://doi.org/10.26434/chemrxiv.11987475.v1. 2020 https://doi.org/10.26434/chemrxiv.11987475.v1

Zhang D, Wu K, Zhang X, Deng S, Peng B, "In silico screening of Chinese herbal medicines with the potential to directly inhibit 2019 novel coronavirus" J. Integr. Med., 2020; 18:152-158. https://doi.org/10.1016/j.joim.2020.02.005

Yinyang J, Mpondo Mpondo E, Tchatat M, Ndjib RC, Mvogo Ottou PB, Dibong SD, "Les plantes à alcaloïdes utilisées par les populations de la ville Douala (Cameroun) " Journal of Applied Biosciences 2014; 78:6600-6619. https://doi.org/10.4314/jab.v78i0.7

Published

2022-09-15
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How to Cite

1.
Mvogo Ottou PBB, Fogang CWS, Ndiang Z, Biyon JBN, Mokake SE, Mbezo FB, et al. Assessment of resilience of aromatic plants during the COVID-19 pandemic in Douala, Cameroon. J. Drug Delivery Ther. [Internet]. 2022 Sep. 15 [cited 2026 Apr. 30];12(5):8-19. Available from: https://jddtonline.info/index.php/jddt/article/view/5580

How to Cite

1.
Mvogo Ottou PBB, Fogang CWS, Ndiang Z, Biyon JBN, Mokake SE, Mbezo FB, et al. Assessment of resilience of aromatic plants during the COVID-19 pandemic in Douala, Cameroon. J. Drug Delivery Ther. [Internet]. 2022 Sep. 15 [cited 2026 Apr. 30];12(5):8-19. Available from: https://jddtonline.info/index.php/jddt/article/view/5580