Pharmacist Care to Improve Medication Adherence and Quality Of Life of COPD Patients
Abstract
The objective of this study was to determine whether pharmaceutical care by pharmacists could improve medication adherence and quality of life in patients with chronic obstructive pulmonary disease or not. A prospective interventional study was conducted among 156 patients to assess medication adherence and find the reason for non-adherence, analyze the quality of life, and provide counseling to improve the quality of life in patients, to determine whether pharmaceutical care by pharmacists could improve medication adherence as well as the quality of life and to prepare patient information leaflet to educate the patients regarding the disease. Prescriptions were collected and Medication Adherence Questionnaire and St. George’s Respiratory Questionnaire were used to assess medication adherence and quality of life respectively. Among 156 patients, 76 were taken as a control group and the other 80 were taken as an intervention group. At the baseline, the patients in both intervention and control groups were found to have no significant difference. After the second follow-up, the total quality of life score was improved significantly in the intervention group when compared with the control group (53.55 ± 6.79 vs.68.89 ± 9.13, p=0.001). Medication adherence was significantly improved after pharmacist intervention (6.38 ± 1.53, 7.42 ± 0.74, p=0.001) as compared with control group(4.73 ± 2.16, 4.89 ± 2.18, p=0.01). As per the study results, the implementation of pharmacist intervention played an important role in improving medication adherence as well as the quality of life of chronic obstructive pulmonary disease patients. It may improve patient outcomes and reduce their social and economic burdens.
Keywords: Pharmacist intervention, Medication adherence, COPD, MAQ, SGRQ.
Keywords:
Pharmacist intervention, Medication adherence, COPD, MAQ, SGRQDOI
https://doi.org/10.22270/jddt.v12i3-S.5505References
Jamie Bryant, Vanessa M McDonald, Allison Boyes, Rob Sanson-Fisher, Christine Paul and Jessica Melville, Improving medication adherence in chronic obstructive pulmonary disease: a systematic review. Respiratory research, 2013; 14(1):109 https://doi.org/10.1186/1465-9921-14-109
Global Initiative for Chronic Obstructive Pulmonary Disease, Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Global Initiative for Chronic Obstructive Lung Disease, 2018. [online], Available athttps://goldcopd.org/wp-content/uploads/2017/11/GOLD-2018-v6.0-FINAL-revised-20-Nov_WMS.pdf.
Jackin R. Moses, Neena Priyamalar E, Shilpa Ravi, Raveena Pachal Balakrishnan, Rajganesh Ravichandran, Lavanya Selvaraj, Impact of clinical pharmacist intervention in chronic obstructive pulmonary disease management, International Journal of Research in Medical Science, 2020; 8(11):3944-3949. https://doi.org/10.18203/2320-6012.ijrms20204883
European COPD Coalition (ECC) Key facts. 2015 [online]. Available at: http://www.copdcoalition.eu/about-copd/key-facts Google Scholar
Nejc Horvat, Igor Locatelli, Mitja Kos, Ana Janezic, Medication adherence and health related quality of life among patients with chronic obstructive pulmonary disease, Actapharmaceutical, 2018; 68(1):117-125. https://doi.org/10.2478/acph-2018-0006
Shrestha R, Pant A, Shrestha S, Shrestha B, Gurung RB, Karmacharya BM, A cross- sectional study of medication adherence pattern and factors affecting the adherence in chronic obstructive pulmonary disease, Kathmandu University Medical Journal, 2015; 13(1): 64-70. https://doi.org/10.3126/kumj.v13i1.13756
Khdour MR, Hawwa AF, Bronagh JCK, Smyth M, McElnay JC, Potential risk factors for medication non-adherence in patients with chronic obstructive pulmonary disease, European journal of clinical pharmacology, 2012; 68(10):1365-1373. https://doi.org/10.1007/s00228-012-1279-5
Abdulsalim S, Kesavan UM, Mohan MK, Alrasheedy AA, Godman B, Morisky DE, Structured pharmacist-led intervention to improve medication adherence in COPD patients: A randomized controlled study. Research in Social and Administrative Pharmacy, 2017; 10:008. https://doi.org/10.1016/j.sapharm.2017.10.008
Mohsen S, Hanafy FZ, Fathy AA, El-Gilany AH, Non-adherence to treatment and quality of life among patients with chronic obstructive pulmonary disease, Lung India: Official Organ of Indian Chest Society, 2019; 6(3):193-198. https://doi.org/10.4103/0970-2113.257719
Faheemuddin MD, Ramaiah B, Kiran SS, Kumari BS, Vijayalaxmi M, Evaluation of medication adherence in COPD patients and their drug utilization pattern, Chronic Obstruct Pulmon Dis, 2016; 1(3):17.
Olah M, Kresznerits S, Gonda Z, Perczel-Forintos, D Szabo M, Csanky E, Meszaros A, Impact of education on dimensions of adherence in patients with chronic obstructive pulmonary disease, Acta Poloniae Pharmaceutica,2020; 77(1):195-204. https://doi.org/10.32383/appdr/114095
Xin C, Xia Z, Jiang C, Lin M, Li G, The impact of pharmacist-managed clinic on medication adherence and health-related quality of life in patients with COPD: a randomized controlled study. Patient preference and adherence, 2016; 10(1):1197-1203. https://doi.org/10.2147/PPA.S110167
Li Wei, Xinyun Yang, Lianghui Liu, Hongying Luo, Zeguang Zheng, Yi Wei, Effect of pharmaceutical care on medication adherence and hospital admission in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled study, JThoracDis,2014; 6(6): 656-62.
Dobbels F, Damme-Lombaert RV, Vanhaecke J, Geest SD, Growing pains: Non-adherence with the immunosuppressive regimen in adolescent transplant recipients. Pediatr Transplantation, 2005; 9:381-390. https://doi.org/10.1111/j.1399-3046.2005.00356.x
Moses JR, Neena Priyamalar E. M., Shilpa Ravi, Raveena Pachal Balakrishnan, Rajganesh Ravichandran, Lavanya Selvaraj, Impact of clinical pharmacist intervention in chronic obstructive pulmonary disease management, International Journal of Research in Medical Sciences, 2020; 8(11):3944. https://doi.org/10.18203/2320-6012.ijrms20204883
Tu-Son Nguyen, Thi Lien Huong Nguyen, Thi Thuy Van Pham, Susan Hua , Quy Chau Ngo, Shu Chuen Li, Impact of pharmaceutical care in the improvement of medication adherence and quality of life for COPD patients in Vietnam. Respiratory medicine, 2019; 153:31-37. https://doi.org/10.1016/j.rmed.2019.05.006
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