Phytochemical Screening, GCMS Profile, and In-silico properties of Bioactive Compounds in Methanolic Leaf Extracts of Moringa oleifera

  • C. Kandeepan PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts and Culture, Palani – 624601, Dindigul District, TamilNadu, India
  • M. Sabitha PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts and Culture, Palani – 624601, Dindigul District, TamilNadu, India
  • K. Parvathi Department of Zoology, Erode Arts and Science College (Autonomous), Erode – 638009, TN, India.
  • N. Senthilkumar Institute of Forest Genetics and Tree Breeding (IFGTB), Indian Council of Forestry Research and Education (ICFRE), Coimbatore – 641002, TamilNadu, India
  • S. Ramya PG Department of Zoology, Yadava College (Men), Thiruppalai - 625014, Madurai, TamilNadu, India
  • NM. Boopathi Centre for Plant Molecular Biology and Biotechnology, Department of Plant Biotechnology, Tamil Nadu Agricultural University, Coimbatore - 641 003, TN, India
  • R. Jayakumararaj Department of Botany, Government Arts College, Melur – 625106, Madurai District, TN, India

Abstract

Plant Based Natural Products (PBNPs) have been subject of interest since ancient time due to their use in food, industrial and biomedical applications. Research attention has further augmented to explore their phytochemical composition, properties, and potential application in the post-COVID era. In the present study phytochemical screening has been carried out with Methanolic Leaf Extracts of Moringa oleifera (MLEMO) followed by Gas Chromatography-Mass Spectrometry (GCMS) analysis. Phytochemical analysis of MLEMO revealed the presence of Alkaloids, Carbohydrates, Coumarins, Flavonoids, Glycosides, Phenol, Proteins, Quinones, Saponins, Steroids, Tannins and Terpenoids. Further, GCMS analysis revealed the presence of 41 compounds of which Dihydroxyacetone; Monomethyl malonate; 4H-Pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl; 1,3-Propanediol, 2-ethyl-2-(hydroxymethyl); Propanoic acid, 2-methyl-, octyl ester; 3-Deoxy-d-mannoic lactone; Sorbitol; Inositol; Cyclohexanemethanol, alpha-methyl-4-(1-methylethyl), Hexadecanoic acid, Methyl palmitate; n-Hexadecanoic acid (Palmitic acid); 9-Octadecenoic acid, methyl ester; Phytol; 9,12,15-Octadecatrienoic acid; Octadecanoic acid; 9-Octadecenamide were prominent. Most of the compounds in the list are bioactive and possess medicinal properties that are expected to serve as a baseline lead for the development of therapeutic agents.


Keywords: Phytochemical screening; GCMS; Bioactive Natural Products; Moringa oleifera; MLEMO; Biomedical application

Keywords: Phytochemical screening, GCMS, Bioactive Natural Products, Moringa oleifera, MLEMO, Biomedical application

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Author Biographies

C. Kandeepan, PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts and Culture, Palani – 624601, Dindigul District, TamilNadu, India

PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts and Culture, Palani – 624601, Dindigul District, TamilNadu, India

M. Sabitha, PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts and Culture, Palani – 624601, Dindigul District, TamilNadu, India

PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts and Culture, Palani – 624601, Dindigul District, TamilNadu, India

K. Parvathi, Department of Zoology, Erode Arts and Science College (Autonomous), Erode – 638009, TN, India.

Department of Zoology, Erode Arts and Science College (Autonomous), Erode – 638009, TN, India.

N. Senthilkumar, Institute of Forest Genetics and Tree Breeding (IFGTB), Indian Council of Forestry Research and Education (ICFRE), Coimbatore – 641002, TamilNadu, India

Institute of Forest Genetics and Tree Breeding (IFGTB), Indian Council of Forestry Research and Education (ICFRE), Coimbatore – 641002, TamilNadu, India

S. Ramya, PG Department of Zoology, Yadava College (Men), Thiruppalai - 625014, Madurai, TamilNadu, India

PG Department of Zoology, Yadava College (Men), Thiruppalai - 625014, Madurai, TamilNadu, India

NM. Boopathi, Centre for Plant Molecular Biology and Biotechnology, Department of Plant Biotechnology, Tamil Nadu Agricultural University, Coimbatore - 641 003, TN, India

Centre for Plant Molecular Biology and Biotechnology, Department of Plant Biotechnology, Tamil Nadu Agricultural University, Coimbatore - 641 003, TN, India

R. Jayakumararaj, Department of Botany, Government Arts College, Melur – 625106, Madurai District, TN, India

Department of Botany, Government Arts College, Melur – 625106, Madurai District, TN, India

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Kandeepan C, Sabitha M, Parvathi K, Senthilkumar N, Ramya S, Boopathi N, Jayakumararaj R. Phytochemical Screening, GCMS Profile, and In-silico properties of Bioactive Compounds in Methanolic Leaf Extracts of Moringa oleifera. JDDT [Internet]. 15Mar.2022 [cited 12Jul.2024];12(2):87-9. Available from: https://jddtonline.info/index.php/jddt/article/view/5250

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