CHARGE TRANSFER COMPLEX METHOD FOR THE ESTIMATION OF ETORICOXIB IN TABLETS

Authors

  • P G Sunitha College of Pharmacy, Madras Medical College, Chennai-600 003
  • N Deattu College of Pharmacy, Madras Medical College, Chennai-600 003
  • R Ravi Kumar College of Pharmacy, Madras Medical College, Chennai-600 003
  • S Sri Rudhra College of Pharmacy, Madras Medical College, Chennai-600 003
  • P Kalaimathi College of Pharmacy, Madras Medical College, Chennai-600 003
  • B Soundiramani College of Pharmacy, Madras Medical College, Chennai-600 003

Abstract

A simple and sensitive spectrophotometric method employing acid-dye technique was developed for the estimation of etoricoxib in pharmaceutical dosage form. The proposed method is based on the formation of ion-pair complex of etoricoxib with an acid dye, which is extracted into chloroform and the absorbance measured at the λmax of the complex. The λmax of the ion-pair complex was found to be 414nm. Beer’s law was obeyed in the concentration range of 10-80 µg/ml .The proposed method is statistically validated and found to be useful for the routine determination of etoricoxib in tablets.

Keywords: Etoricoxib, Spectrophotometry, Charge transfer complex, Tablets, Validation.

DOI

https://doi.org/10.22270/jddt.v3i3.524

Published

13-05-2013
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How to Cite

1.
Sunitha PG, Deattu N, Kumar RR, Rudhra SS, Kalaimathi P, Soundiramani B. CHARGE TRANSFER COMPLEX METHOD FOR THE ESTIMATION OF ETORICOXIB IN TABLETS. J. Drug Delivery Ther. [Internet]. 2013 May 13 [cited 2025 Mar. 27];3(3):98-9. Available from: https://jddtonline.info/index.php/jddt/article/view/524

Issue

Vol. 3 No. 3 (2013): Volume 3, Issue 3, May-June 2013

Section

Research

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How to Cite

1.
Sunitha PG, Deattu N, Kumar RR, Rudhra SS, Kalaimathi P, Soundiramani B. CHARGE TRANSFER COMPLEX METHOD FOR THE ESTIMATION OF ETORICOXIB IN TABLETS. J. Drug Delivery Ther. [Internet]. 2013 May 13 [cited 2025 Mar. 27];3(3):98-9. Available from: https://jddtonline.info/index.php/jddt/article/view/524
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