ENHANCEMENT OF IMMUNE RESPONSES BY PROBIOTIC PROPERTIES OF LACTOBACILLUS ACIDOPHILUS NCDC 195
Abstract
Probiotics are microbial food supplements with beneficial effects on human health. Along with the dietary supplement, probiotics also have immunomodulatory properties. Present study was carried out using the in-vivo utilization of albino mice for the study of immunomodulatory effect of Lactobacillus acidophilus NCDC 195. To estimate the increase immune responses Nitroblue Tetrazolium reduction test, (Inducible Nitric Oxide synthase) test and Phagocytosis (% age) have been studied. Results were compared with the control value and. It was observed that feeding the Swiss albino mice for 15 days with Probiotic dosage (Yogurt), causes 1.98 times increase in Nitroblue Tetrazolium reduction test as compared to control, whereas Inducible Nitric Oxide synthase and phagocytosis shows 1.71 and 1.82 times increase in immune responses respectively. Cell mediated immune response was also calculated, where there was increase of 1.04, 1.07 and 1.02 times in Delayed Type Hypersensitivity (DTH) as compared to control was observed.
Keywords: Immunomodulation, Nitroblue Tetrazolium (NBT) reduction, Probiotic, Phagocytosis, Cell mediated immune response, Inducible Nitric Oxide synthetase.DOI
https://doi.org/10.22270/jddt.v3i3.510
Published
Abstract Display: 477 
PDF Downloads: 632 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.