Evaluation of Selected Flavonoids for the Anthelmintic and Skeletal Muscle Relaxant Activity using Animal Models

  • S Bala Yaswanth Kumar ⅤI Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India https://orcid.org/0000-0002-9255-7361
  • Suranjan Bantupalli ⅤI Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India https://orcid.org/0000-0001-6148-7180
  • Deekshit Atluri ⅤI Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India https://orcid.org/0000-0002-5329-1476

Abstract

Most fruits and vegetables contain flavonoids, a type of phytonutrient. As well as carotenoids, they're responsible for fruits and vegetable brilliant hues. Some other phytonutrients such as flavonoids are strong antioxidants with anti-inflammatory and immune properties. There are many flavonoids, including anthocyanins, flavones, flavonols, flavonoids, and isoflavonoids. Quercetin and chrysin were chosen for the investigation. Humans and other animals can contract Helminthiasis (helminthiases), sometimes known as worm infection. Tapeworms, roundworms, and flukes are only a few of the parasites that exist. Skeletal muscle relaxants are used to treat spasticity caused by upper motor neuron syndromes and muscle discomfort or musculoskeletal spasms created by peripheral disturbances. Samples of quercetin and chrysin were generated in the presence of 0.5% SCMC suspension at concentrations of 10, 20, 30, and 40 mg/ml, and then analyzed. To keep track of photocell beam disruptions, a six-digit counter was utilized (locomotor activity). It was time to turn on the actophotometer and examine the locomotor behavior of each rat for five minutes. The basal activity levels of all the animals were recorded.


Keywords: Flavonoids, Anthelmintic, Skeletal Muscle relaxant, animal models

Keywords: Flavonoids, Anthelmintic, Skeletal Muscle relaxant, animal models

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Author Biographies

S Bala Yaswanth Kumar, ⅤI Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

I Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

Suranjan Bantupalli, ⅤI Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

I Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

Deekshit Atluri, ⅤI Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

I Year Pharm.D, Kommareddy Venkata Sadasiva Rao Siddhartha College of Pharmaceutical Sciences, Vijayawada-520010, Andhra Pradesh, India

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Bala Yaswanth Kumar S, Bantupalli S, Atluri D. Evaluation of Selected Flavonoids for the Anthelmintic and Skeletal Muscle Relaxant Activity using Animal Models. JDDT [Internet]. 15Nov.2021 [cited 1Dec.2021];11(6):127-34. Available from: https://jddtonline.info/index.php/jddt/article/view/5070