A Review on Niosomes: Potential Vesicular Drug Delivery System
Abstract
Over the years researchers have been making an attempt to improve the potency of utilization of medicament for treatment of numerous diseases. During this endeavour, drug delivery systems have helped greatly by achieving reduced dose, reduced dosage frequency, improved patient compliance, improved bioavailability and maximum concentration of the drug at the target site. Recent years have seen an unprecedented growth in the use of nanotechnology in designing drug delivery systems. Niosomes are vesicles composed of non-ionic surfactants, which are biodegradable, comparatively non-toxic, stable, economical and effective alternate to liposomes. This review is deepening and widening the interest of Niosomes in several scientific disciplines and notably its application in drug delivery. This review additionally presents a summary of the types, methods of preparation, characterization and applications of Niosomes.
Keywords: Niosomes, types, method of preparation, factors affecting and applications
Keywords:
Niosomes, types, method of preparation, factors affecting and applicationsDOI
https://doi.org/10.22270/jddt.v11i5.5046References
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3. Khan R, Irchhaiya R, "Niosomes: a potential tool for novel drug delivery" JPI, 2016; 46(13):195-204. https://doi.org/10.1007/s40005-016-0249-9
4. Ag Seleci D, Seleci M, Walter J, Stahl F, Scheper T, "Niosomes as nanoparticular drug carriers: fundamentals and recent applications" JN, 2016; 1-13. https://doi.org/10.1155/2016/7372306
5. Bhardwaj P, Tripathi P, Gupta R, Pandey S, "Niosomes: a review on niosomal research in the last decade" JDDST, 2020; 56:101581. https://doi.org/10.1016/j.jddst.2020.101581
6. Yeo P, Lim C, Chye S, Kiong Ling A, Koh R, "Niosomes: a review of their structure, properties, methods of preparation, and medical applications" AB, 2017;11(4):301-314. https://doi.org/10.1515/abm-2018-0002
7. Yadav S, Mishra M, Verma G, Nayak K, Tiwari A, Shukla A, "Niosomes: an approach towards targeted drug delivery system" IJIPLS, 2016; 6(6):39- 52.
8. Vadlamudi HC, Sevukarajan M, "Niosomal drug delivery- a review" IAJPR, 2012; 2(9).
9. Kuotsu K, Karim K, Mandal A, Biswas N, Guha A, Chatterjee S, "Niosome: a future of targeted drug delivery systems" JAPTR, 2010; 1(4): 374. https://doi.org/10.4103/0110-5558.76435
10. Usman M, Ramdas K, Baviskar K, "Pesticides: an overeview." JDDT, 2017; 7(4):1-5. https://doi.org/10.22270/jddt.v7i4.1462
11. Rao N, Chowdary P, Divya Y, Laksmi T, Latha K, Sirisha P, "Niosomes: a vesicular drug delivery system" RJPT, 2018; 11(8):3731- 3736. https://doi.org/10.5958/0974-360X.2018.00684.4
12. Kamal M, Maher M, Ibrahim A, Louis D, "An overview on niosomes: a drug nanocarrier" DDIPIJ, 2018; 1(5):1-9.
https://doi.org/10.32474/DDIPIJ.2018.01.000125
13. Mujoriya R, Dhamandeb K, Bodlac D, "Niosomal drug delivery system - a review" IJAP, 2011; 3(3):7-10.
14. Ahmad S, Teotia D, Kumar K, "Niosomes - a promising carrier for drug delivery" IJRDPLS, 2018; 7(4):3015-3021. https://doi.org/10.21276/IJRDPL.2278-0238.2018.7(4).3015-3021
15. Rai A, Alam G, Singh A, Verma N, "Niosomes: an approach to current drug delivery-a review" IJAP, 2017; 06(02):41-48.
16. Moghassemi S, Hadjizadeh A, "Nano-niosomes as nanoscale drug delivery systems: an illustrated review" JCR, 2014; 185:22-36. https://doi.org/10.1016/j.jconrel.2014.04.015
17. Sanklecha V, Pande V, Pawar S, Pagar O, Jadhav A, "Review on niosomes" APP, 2018; 3(2):1-7.
18. Chen S, Hanning S, Falconer J, Locke M, Wen J "Recent advances in non-ionic surfactant vesicles (niosomes): fabrication, characterization, pharmaceutical and cosmetic applications" EJPB, 2019; 144:18-39. https://doi.org/10.1016/j.ejpb.2019.08.015
19. Sharma D, Ali A, Aate J, "Niosomes as novel drug delivery system: review article" P, 2018; 6(3):58. https://doi.org/10.29161/PT.v6.i3.2018.58
20. Yadav J, Kulkarni P, Vaidya K, Shelke G, "Niosome: a review" JPR, 2011; 4(3):632-636.
21. Sraswathi TS, Mothilal M, Jaganathan MK, "Niosomes an emerging formulation tool for drug delivery-a review" IJAP, 2019; 11(2):7-15. https://doi.org/10.22159/ijap.2019v11i2.30534
22. Khalifa F, Khalifa A, Jeganath S, Nitish B, "Niosomes as target drug delivery system: a review" IJRPS, 2020; 11(3):3198-3203. https://doi.org/10.26452/ijrps.v11i3.2435
23. Patel H, .Patel U, "Review on niosomes - a novel approach for drug targeting" IJAP, 2019; 08(01):1-6.
24. Kaur D, Kumar S, "Niosomes: present scenario and future aspects" JDDT, 2018; 8(5):35-43. https://doi.org/10.22270/jddt.v8i5.1886
25. Khanam N, Alam M, Sachan A, Gangwar S, Sharma R, "Recent trends in drug delivery by niosomes: a review" AJPRD, 2013; 1(3):115-122.
26. Mishra N, Srivastava V, Kaushik A, Chauhan, V, Srivastava G, "Formulation and in-vitro evaluation of niosomes of Aceclofenac" JSIR, 2014; 3(3):337-341.
27. Kumar G, Rajeshwarrao P, "Nonionic surfactant vesicular systems for effective drug delivery - an overview" APSB, 2011; 1(4):208-219. https://doi.org/10.1016/j.apsb.2011.09.002
28. Sudheer P, Kaushik K, "Review on niosomes - a novel approach for drug targeting" JPR, 2015; 14(1):20-25. https://doi.org/10.18579/jpcrkc/2015/14/1/78376
2. Rajera R, Nagpal K, Singh S, Mishra D, "Niosomes: a controlled and novel drug delivery system" BPB, 2011; 34(7):945-953. https://doi.org/10.1248/bpb.34.945
3. Khan R, Irchhaiya R, "Niosomes: a potential tool for novel drug delivery" JPI, 2016; 46(13):195-204. https://doi.org/10.1007/s40005-016-0249-9
4. Ag Seleci D, Seleci M, Walter J, Stahl F, Scheper T, "Niosomes as nanoparticular drug carriers: fundamentals and recent applications" JN, 2016; 1-13. https://doi.org/10.1155/2016/7372306
5. Bhardwaj P, Tripathi P, Gupta R, Pandey S, "Niosomes: a review on niosomal research in the last decade" JDDST, 2020; 56:101581. https://doi.org/10.1016/j.jddst.2020.101581
6. Yeo P, Lim C, Chye S, Kiong Ling A, Koh R, "Niosomes: a review of their structure, properties, methods of preparation, and medical applications" AB, 2017;11(4):301-314. https://doi.org/10.1515/abm-2018-0002
7. Yadav S, Mishra M, Verma G, Nayak K, Tiwari A, Shukla A, "Niosomes: an approach towards targeted drug delivery system" IJIPLS, 2016; 6(6):39- 52.
8. Vadlamudi HC, Sevukarajan M, "Niosomal drug delivery- a review" IAJPR, 2012; 2(9).
9. Kuotsu K, Karim K, Mandal A, Biswas N, Guha A, Chatterjee S, "Niosome: a future of targeted drug delivery systems" JAPTR, 2010; 1(4): 374. https://doi.org/10.4103/0110-5558.76435
10. Usman M, Ramdas K, Baviskar K, "Pesticides: an overeview." JDDT, 2017; 7(4):1-5. https://doi.org/10.22270/jddt.v7i4.1462
11. Rao N, Chowdary P, Divya Y, Laksmi T, Latha K, Sirisha P, "Niosomes: a vesicular drug delivery system" RJPT, 2018; 11(8):3731- 3736. https://doi.org/10.5958/0974-360X.2018.00684.4
12. Kamal M, Maher M, Ibrahim A, Louis D, "An overview on niosomes: a drug nanocarrier" DDIPIJ, 2018; 1(5):1-9.
https://doi.org/10.32474/DDIPIJ.2018.01.000125
13. Mujoriya R, Dhamandeb K, Bodlac D, "Niosomal drug delivery system - a review" IJAP, 2011; 3(3):7-10.
14. Ahmad S, Teotia D, Kumar K, "Niosomes - a promising carrier for drug delivery" IJRDPLS, 2018; 7(4):3015-3021. https://doi.org/10.21276/IJRDPL.2278-0238.2018.7(4).3015-3021
15. Rai A, Alam G, Singh A, Verma N, "Niosomes: an approach to current drug delivery-a review" IJAP, 2017; 06(02):41-48.
16. Moghassemi S, Hadjizadeh A, "Nano-niosomes as nanoscale drug delivery systems: an illustrated review" JCR, 2014; 185:22-36. https://doi.org/10.1016/j.jconrel.2014.04.015
17. Sanklecha V, Pande V, Pawar S, Pagar O, Jadhav A, "Review on niosomes" APP, 2018; 3(2):1-7.
18. Chen S, Hanning S, Falconer J, Locke M, Wen J "Recent advances in non-ionic surfactant vesicles (niosomes): fabrication, characterization, pharmaceutical and cosmetic applications" EJPB, 2019; 144:18-39. https://doi.org/10.1016/j.ejpb.2019.08.015
19. Sharma D, Ali A, Aate J, "Niosomes as novel drug delivery system: review article" P, 2018; 6(3):58. https://doi.org/10.29161/PT.v6.i3.2018.58
20. Yadav J, Kulkarni P, Vaidya K, Shelke G, "Niosome: a review" JPR, 2011; 4(3):632-636.
21. Sraswathi TS, Mothilal M, Jaganathan MK, "Niosomes an emerging formulation tool for drug delivery-a review" IJAP, 2019; 11(2):7-15. https://doi.org/10.22159/ijap.2019v11i2.30534
22. Khalifa F, Khalifa A, Jeganath S, Nitish B, "Niosomes as target drug delivery system: a review" IJRPS, 2020; 11(3):3198-3203. https://doi.org/10.26452/ijrps.v11i3.2435
23. Patel H, .Patel U, "Review on niosomes - a novel approach for drug targeting" IJAP, 2019; 08(01):1-6.
24. Kaur D, Kumar S, "Niosomes: present scenario and future aspects" JDDT, 2018; 8(5):35-43. https://doi.org/10.22270/jddt.v8i5.1886
25. Khanam N, Alam M, Sachan A, Gangwar S, Sharma R, "Recent trends in drug delivery by niosomes: a review" AJPRD, 2013; 1(3):115-122.
26. Mishra N, Srivastava V, Kaushik A, Chauhan, V, Srivastava G, "Formulation and in-vitro evaluation of niosomes of Aceclofenac" JSIR, 2014; 3(3):337-341.
27. Kumar G, Rajeshwarrao P, "Nonionic surfactant vesicular systems for effective drug delivery - an overview" APSB, 2011; 1(4):208-219. https://doi.org/10.1016/j.apsb.2011.09.002
28. Sudheer P, Kaushik K, "Review on niosomes - a novel approach for drug targeting" JPR, 2015; 14(1):20-25. https://doi.org/10.18579/jpcrkc/2015/14/1/78376
Published
15-09-2021
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Kumavat S, Sharma PK, Koka SS, Sharma R, Gupta A, Darwhekar GN. A Review on Niosomes: Potential Vesicular Drug Delivery System. J. Drug Delivery Ther. [Internet]. 2021 Sep. 15 [cited 2025 Apr. 30];11(5):208-12. Available from: https://jddtonline.info/index.php/jddt/article/view/5046
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How to Cite
1.
Kumavat S, Sharma PK, Koka SS, Sharma R, Gupta A, Darwhekar GN. A Review on Niosomes: Potential Vesicular Drug Delivery System. J. Drug Delivery Ther. [Internet]. 2021 Sep. 15 [cited 2025 Apr. 30];11(5):208-12. Available from: https://jddtonline.info/index.php/jddt/article/view/5046
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