Formulation and Evaluation of Curcumin Gel Sanitizer
CURCUMIN GEL SANITIZER
Abstract
Objective: the main intention of this research is to prepare a curcumin based herbal gel sanitizer by minimizing the alcoholic usage and to evaluate the anti-bacterial activity of this herbal sanitizer. Methods: curcumin gel sanitizer was prepared from the ethanolic extract of Curcuma longa along with addition of gel base prepared from the combination of carbapol-940 and HPMC-E15. Results: The curcumin gel sanitizer was formulated and evaluated for its phytochemical constituents present in curcumin, detection of active constituent of curcumin which was majorly responsible for the anti-microbial activity through HPTLC, organoleptic properties, irritancy test and the efficiency of anti-bacterial activity of curcumin was also evaluated and it is safe and effective against pathogens. Conclusion: As a natural herb, curcumin which was a household ingredient could also be effectively formulated as a sanitizer that reduces the side effects of alcoholic sanitizer products and is a best source that acts effectively against a numerous pathogens.
Keywords: curcumin, carbapol-940, Ethanolic extract, HPMC-E15 (hydroxypropyl methylcellulose), HPTLC, Pathogens,
Keywords:
curcumin, carbapol-940, Ethanolic extract, HPMC-E15 (hydroxypropylmethylcellulose), HPTLC,, PathogensDOI
https://doi.org/10.22270/jddt.v11i4-S.4985References
Singla D, Saini K. Formulation of an Herbal Substitute for Chemical Sanitizer and its Evaluation for Antimicrobial Efficiency. International Journal of ChemTech Research. 2019; 12(3):114-20. https://doi.org/10.20902/IJCTR.2019.120318
Nandini N. Herbal hand Sanitizer for management of Indoor bioaerosol and touch surfaces. Journal of Pharmacognosy and Phytochemistry. 2020; 9(3):1171-5.
Jing JL, Pei Yi T, Bose RJ, McCarthy JR, Tharmalingam N, Madheswaran T. Hand sanitizers: a review on formulation aspects, adverse effects, and regulations. International journal of environmental research and public health. 2020 Jan; 17(9):3326. https://doi.org/10.3390/ijerph17093326
Chakraborty A, Mukhopadhyay A, Sur A, Ghosh S. Production of cheap hand sanitizer with herbal ingredients. InJournal of Physics: Conference Series 2021 Feb 1 (Vol. 1797, No. 1, p. 012036). IOP Publishing. https://doi.org/10.1088/1742-6596/1797/1/012036
Nurjanah N, Saepudin E. Curcumin isolation, synthesis and characterization of curcumin isoxazole derivative compound. InAIP Conference Proceedings 2019 Nov 4 (Vol. 2168, No. 1, p. 020065). AIP Publishing LLC. https://doi.org/10.1063/1.5132492
Harismah K, Ariningrum ND, Fuadi AM, Mujiburohman M, Mirzaei M. Formulation and Evaluation of Herbal Hand Sanitizer Based on Stevia (Stevia rebaudiana). InJournal of Physics: Conference Series 2021 Apr 1 (Vol. 1858, No. 1, p. 012053). IOP Publishing. https://doi.org/10.1088/1742-6596/1858/1/012053
Alghamdi HA. A need to combat COVID-19; herbal disinfection techniques, formulations and preparations of human health friendly hand sanitizers. Saudi Journal of Biological Sciences. 2021 Apr 9. https://doi.org/10.1016/j.sjbs.2021.03.077
Thorat Y, Kumbhar S, Matole V, Birajdar A, Madur S, Patil S, Shegaonkar A. Formulation and Evaluation of Neem extract Hand Sanitizer. Asian Journal of Pharmacy and Technology. 2020 Sep 1; 10(3). https://doi.org/10.5958/2231-5713.2020.00023.9
Sharma SK, Rahat I. Oregano Derived Anti-Bacterial Hand Sanitizer: Formulation and Characterization. Journal of Pharmaceutical Research International. 2020:64-72. https://doi.org/10.9734/jpri/2020/v32i3931025
Osei-Asare C, Oppong EE, Apenteng JA, Adi-Dako O, Kumadoh D, Akosua AA, Ohemeng KA. Managing Vibrio cholerae with a local beverage: preparation of an affordable ethanol based hand sanitizer. Heliyon. 2020 Jan 1; 6(1):e03105. https://doi.org/10.1016/j.heliyon.2019.e03105
Suryawanshi VR, Surani HC, Yadav HR. Formulation, evaluation and anti-microbial efficiency of alcohol based herbal hand sanitizer. Int J Eng Sci Comput. 2020; 12:25113-15.
Balkrishna A, Singh K, Singh H, Haldar S, Varshney A. GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria. AMB Express. 2020 Dec; 10(1):1-8. https://doi.org/10.1186/s13568-020-01151-y
Govindwar MN. Phytochemical and Antibacterial Evaluation of Formulated Hand Sanitizer from different Natural Sources and Waste materials.
Azad MM, Al Mahmud A, Islam MS, Gouhar AI. Common sage (Salvia officinalis) antiviral role: potentiality of a Unani hand sanitizer in COVID-19 (corona virus) second wave control. Asian Journal of Medical and Biological Research. 2020; 6(4):611-7. https://doi.org/10.3329/ajmbr.v6i4.51225
Subramanian A. Case Study Testing the Antibacterial Efficacy Between Alcohol-Based and Alcohol-Free Sanitizer on the Human Hand. June 23, 2020.
Ranganathan V, Kumar PS, Vijayakaran K, Elamaran A. Evaluation of curcumin compound from methanolic extracts of Curcuma longa by high performance thin layer chromatography. Journal of Pharmacognosy and Phytochemistry. 2020; 9(2):1931-4.
Asati S, Chandel V, Choubey A. extraction and comparative study on physico-chemical, phytochemical analysis of fruits of Terminalia chebula and rhizomes of Curcuma longa. Plant Archives. 2020; 20(2):4289-94.
Bhogaonkar MD. HPTLC fingerprinting of phenolics profile of three Curcuma species; Vol. 8, Issue 2, Part B (2020)
Shaikh F, Bhosale P, Snehal. Formulation and Evaluation of Herbal Hand Sanitizer Using Psidium guajava Leaves Extract. International Journal of Pharmaceutical Sciences Review and Research. 2020; 62(2):37-39.
Published
Abstract Display: 1440 
PDF Downloads: 1054 PDF Downloads: 164 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.