Evaluation of Analgesic Effect of Unani Pharmacopoeial Formulation Habb-E-Suranjan and Raughan-E-Suranjan in Wajaul Mafasil (Joints Pain) Patients: An Open Prospective Clinical Trial
Effect of Unani formulations in Wajaul Mafasil (Joints Pain)
Abstract
Wajaul Mafasil (joint pain) is the most prevalent and common cause of morbidity and disability not only in India but also throughout the world. In spite of various scientific developments in conventional medicine, there is no specific therapy or cure available for joints pain particularly when the disease has progressed to chronic stage. Therefore, it is the need of the hour to explore new formulations from herbal sources which are safe and effective. The present trial was undertaken to scientifically validate the Unani pharmacopoeial compound formulations of Habb-e-Suranjan and Raughan-e-Suranjan for its safety and efficacy in patients with joints pain.
Patients with joint pain, who gave written informed consent, were recruited in the study from general OPD of RRIUM, Chennai with the prior approval of the Institutional Ethics Committee. 97 patients completed the study treatment. The treatment protocol was followed for 14 days and the clinical evaluation was done on seventh and fourteenth day of the treatment. At the end of fourteenth day intensity of individual parameters like joints pain, swelling, tenderness and restriction of movement showed statistically significant improvement (p<0.05). Overall therapeutic response of the treatment observed in this study was 100%. It was observed that 47.4% cases were completely relieved; 51.4% cases were relieved while 1.2% cases showed partial relief after the treatment. The laboratory investigations showed that the drugs used in the study were safe as evident by its maintenance. It may be concluded that Habb-e-Suranjan in combination with Raughan-e-Suranjan possesses significant analgesic property and may be a better option for the patients of joint pain.
Keywords: Arthritis, Joints pain, Wajaul Mafasil, Habb-e-Suranjan, Raughan-e-Suranjan
Keywords:
Arthritis, Joints pain, Wajaul Mafasil, Habb-e-Suranjan, Raughan-e-SuranjanDOI
https://doi.org/10.22270/jddt.v11i2-S.4806References
Mohammad SH, Faseehuzzaman, Jabeen A, Siddiqui MA. Management of Waja-ul-Mafasil (Arthritis) in Unani system of Medicine- A Review. Int. J. Res. Ayurveda Pharm, 2014; 5 (1):60 – 64.
Finney A, Dziedzic KS, Lewis M and Healey E. Multisite peripheral joint pain: a cross-sectional study of prevalence and impact on general health, quality of life, pain intensity and consultation behavior. BMC Musculoskeletal Disorders, 2017; 18:535
Rahila Ashraf, Roohi Mohi-ud-din. Unani aspect of arthritis (Waja-ul-Mafasil) & its management: A review, International Journal of Herbal Medicine, 2018; 6(3).
Munjal YP. API Textbook of Medicine. 9th Ed. Jaypee Brothers Medical Publishers (P) Ltd. New Delhi; 2012: 1818, 1822, 1823.
Faris, A. A. (2010) Therapeutic Evaluation of a Unani Formulation in Waja‘al-Mafāsil with Special Reference to estimation of retinol and tocopherol in patients, Department of Moalijat, Faculty of Medicine, Jamia Hamdard. New Delhi. p. 104-106.
Masuya, Y. B. (1994) Al Mushajjar ul Kabir (Arabic), Khuda Bakhsh Oriental Public Library, Patna. p. 316-319.
Majusi, A. A. (1889) Kamil-us-Sana (Urdu translation), Matba Munshi Nawal Kishore, Lucknow. (2): 503-513, 521-522, 531-534.
Qarah, S. B. (1928) Kitabul Dhakheera Fi Ilmut Tibb (Arabic), Al Matba ul Ameeriya, Cairo. p. 122-126.
Razi, Z. Kitab-al-Hawi Fit Tibb (Urdu translation), CCRUM, New Delhi. 2004; (11):75-188.
Rushd, I. (1987) Kitab al Kulliyat (Urdu translation), CCRUM, New Delhi. p. 384-385, 420-421.
Siddiqui, M. K. (2009) Unani Treatment of Waja-al-Mafasil, CCRUM, M/o. AYUSH New Delhi. p. 235-237
Tabri, A. R. (1417) Firdaus al Hikmat (Urdu translation), Sheikh Mohammad Bashir & Sons, Lahore. p. 291-293,308.
Jurjani A.H (2010), Zakheera Khawarzam Shahi (Urdu Translation), Idara Kitabush Shifa, New Delhi, Volume VI, pp. 635-647.
Sina I (2004), Al Qanoon fit tibb (Urdu Translation), Idara Kitabush Shifa, New Delhi, Volume III, pp. 1119-1132.
Antaki D. TadhkiraAululAlbab (Arabic). Cairo: MaktabawaMatba Mohammad Ali SabeehwaAwlad; 1282 AH. p. 95-99
Kabiruddin, M. (2007) Moalijat Sharhe Asbab, Aijaz Publication House, New Delhi, Vol.3, pp. 164-165
Kabeeruddin, M. (2003) Alakseer, Aijaz Publishing House, Delhi, Vol.5, pp.1431-47.
Baig MG, Quamri MA, Ali J, Imtiyaz S, Sheeraz M, Zaheer N. Concept and Management of Waja-ul-Mafasil (Arthritis) in Greco Arabic Medicine- An Overview. Int J Cur Res Rev, 2014; 6 (20):41-47.
Kabiruddin (2005): Bayaz Kabir, Vol.II, Central Council for Research in Unani Medicine, New Delhi. pp50, 94.
Anonymous (1967): Qarabadeen Sarkari, Part II, Department of ISM, Govt. of AP., Hyderabad. pp. 45-46.
Anonymous (2006), National Formulary of Unani Medicine, Part I, Central Council for Research in Unani Medicine, Ministry of Health and family welfare, (Dept. of AYUSH) Govt. of India. 1st reprint,. pp. 200.
Mohammad I A, Tasleem A, Mohammad W A, Aisha P, Hashmat I, Nighat A, Naheed P.A. Clinical Study of Safety and Efficacy of Unani Pharmocopoeial Formulations of Habb-e-Suranjan and Raughan-e-Suranjan as Anti-arthritic Effect in Waja-al-Mafasil (Joints Pain), Hippocratic Journal of Unani Medicine, 2018; 13 (1): 9-16.
Anonymous (2008), The burden of pain among adults in the United States, Ptzer facts Findings from the National Health and Nutrition Examination Survey, the National Health Care Surveys, and the National Health Interview Survey, USA
Srikanth VK, Fryer JL, Zhai G, Winzenberg TM, Hosmer D, Jones G; A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis; Osteoarthritis and Cartilage, 2005; 13(9):769-781. https://doi.org/10.1016/j.joca.04.014
Akhtar H, Husain SZ. Evaluation of Habb-e-Suranjan in Management of Primary Gout (Niqras). Journal of Ayurvedic and Herbal Medicine, 2019; 5(3):90-95.
Suhail S, jamil S, Jilani S, Ansari S, Yousuf A. Phytochemical and Pharmacological review of Suranjan shireen (Colchicum autumnale). Indo American Journal of Pharmaceutical Research, 2017; 7 (4):8492-96.
Suhail S, jamil S, Jilani S, Jahangir U, Qamar MW. Habb-e-Suranjaan: A classical analgesic Unani formulation. Int J Adv Pharm Med Bio allied Sci. 2017; Vol. 2017; Issue 2017, Article ID 127: 1-6.
Ghazanfar K, Dar SA, Nazir T, Akbar S. Sub chronic oral toxicity study of Habb-e-Suranjan in albino Wistar rats. Journal of Complementary and Integrative Medicine, 2018; DOI:10.1515/jcim-2017-0144.
Khan AA, Bashir F, Akhtar J, Anjum N, Shah Alam. Concept and Management of Waja‘al-Mafasil (Arthritis) in Unani System of Medicine. Journal of Drug Delivery & Therapeutics, 2019; 9(2-s):634-639
Published
Abstract Display: 1720 
PDF Downloads: 890 PDF Downloads: 458 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.