Antimicrobial Activity of Andrographis alata (Vahl) Nees
The medicinal properties of plants could be based on their pharmacological effects of the phytochemicals present in them. Hence plant derived antimicrobial properties have received considerable attention in recent years. In the present study, an attempt has been made to screen the antimicrobial potential of Andrographis alata (entire plant), against diseases causing bacterial and fungal pathogens. The results revealed that the methanol extract had an effective antimicrobial activity against all the tested microorganisms and the hexane extract had low antimicrobial activity. Further studies should be carried out to evaluate the other biological active potentials of Andrographis alata.
Keywords: Antimicrobial activity, Andrographis alata, Entire plant extracts.
2. Boyd RF. Basic Medical Microbiology (5th Edition). Little, Brown and Company, Boston, 1995; 310-314.
3. Cookson BD. Methicillin-resistant Staphylococcus aureus in the community: New battlefronts, or are the battles lost? Control of Hospital Epidemiology, 2000; 21:398-403.
4. The Plant List. 2021. The Plant List: A working list of plant species, version 1. http://theplantlist.org/. Accessed on 17th April, 2021.
5. Irobi ON, Moo-youg M, Anderson WA & Daramola SO. Antibacterial activity of bark extracts of Bridelia ferruginea. Journal of Ethnopharmacology, 1994; 43:223-224.
6. De Boer HJ, Kool A, Broberg A, Mziray WR, Hedberg I & Levenfors JJ. Antifungal and antibacterial activity of some herbal remedies from Tanzania. Journal of Ethnopharmacology, 2005; 96:461-469.
7. Poornima N, Umarajan KM & Babu K. Studies on anatomical and phytochemical analysis of Oxystelma esculentum (L.f.) R.Br. ex. Schultes. Botany Research International, 2009; 2(4):239-243.
8. Ismail Shareef M & Leelavathi S. Evaluation of antioxidant activity of Anisolmeles malabarica R.Br. and Clerodendrum serratum L. extracts against rheumatism. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2011; 2(4):488-495.
9. Annie Felicia F & Muthulingam M. Phytochemical and HPTLC studies of methanolic extract of Indigofera tinctoria (Fabaceae). International Journal of Pharmacy and Life Sciences, 2012; 3(5):1670-1674.
10. Ilango K, Maharajan G & Narasimhan S. Preliminary phytochemical screening and antibacterial activity of fruit pulp of Momordica dioica Roxb. (Cucurbitaceae). African Journal of Basic & Applied Sciences, 2012; 4(1):12-15.
11. Usha M, Appavoo MR & Immanuel G. Pharmacognostical study and preliminary phytochemical screening of the leaf of Ixora johnsonii Hook.f. - A rare, endemic, critically endangered species of southern Western Ghats of Kerala, India. International Journal of Pharmaceutical and Phytopharmacological Research, 2012; 5:263-270.
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