Assessment of Risk Factors and Management Associated with Preterm Deliveries and their Outcomes in Tertiary Care Teaching Hospital

  • T. Lakshmi Susheela Associate Professor and HOD, Department of Obstetrics & Gynaecology, Govt. General Hospital-RIMS, Kadapa, Andhra Pradesh, India
  • Meda. Venkata Subbiah Associate Professor, Department of Pharmacy Practice, P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India
  • M. Ahamadi Tabasum (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India
  • P. Amreen Khan (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India
  • M.V. Swetha Kumari (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India
  • E. Kiranmai (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

Abstract

Background: Preterm is a major obstetrical challenge of health care. It is the top most cause of perinatal morbidity and mortality of neonatal deaths. The births of these neonates are at a greater risk of developmental disabilities, health and growth problems than neonates of full term.


Aim and objective: To assess the risk factors and management associated with preterm deliveries and their outcomes.


Materials & Methods: “A prospective observational cohort study” was conducted over a period of 6 months on 80 Preterm subjects, who were enrolled based on inclusion and exclusion criteria. A detailed questionnaire was used to record socio-demographic, clinical profile and prescribing management. Statistical analysis was performed by percentage method using parameters like mean, standard deviation.


Results: The impact of incidence range in the present study was 31.52%. Maximum preterm deliveries were observed in the age group of 18-23 years (44%). Multiparous woman was at more risk for preterm i.e., about 51%. The commonest risk factor for preterm was Anemia (45%) followed by Pre-eclampsia (24%). The treatment prescribed for preterm was Betamethasone, Tidilon, Magnesium sulphate, Progesterone. The commonest neonatal outcome was found to be low birth weight with KMC and supplements of vitamins, iron, calcium as a therapy for their better recovery.


Conclusion: The study suggests an urgent need for strengthening effective guidelines and appropriate counselling for prevention of preterm. Maintenance of good hygiene, adequate   bed rest and proper antenatal care visits for the better outcomes. 


Keywords: preterm, multiparous, risk factors, neonatal outcomes, antenatal care, cohort.

Keywords: preterm, multiparous, risk factors, neonatal outcomes, antenatal care, cohort

Downloads

Download data is not yet available.

Author Biographies

T. Lakshmi Susheela, Associate Professor and HOD, Department of Obstetrics & Gynaecology, Govt. General Hospital-RIMS, Kadapa, Andhra Pradesh, India

Associate Professor and HOD, Department of Obstetrics & Gynaecology, Govt. General Hospital-RIMS, Kadapa, Andhra Pradesh, India

Meda. Venkata Subbiah, Associate Professor, Department of Pharmacy Practice, P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

Associate Professor, Department of Pharmacy Practice, P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

M. Ahamadi Tabasum, (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

(Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

P. Amreen Khan, (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

(Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

M.V. Swetha Kumari, (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

(Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

E. Kiranmai, (Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

(Pharm. D Intern)., P Rami Reddy Memorial College of Pharmacy, Kadapa, Andhra Pradesh, India

References

[1] Hiralal Konar. DC Dutta’s Textbook of Obstetrics. 8th Edition. New Delhi: Jayapee brothers’ medical publishers; 2019: 376-379.
[2]Grace S. Chung Ryan Lawrence, MD, Kenneth A.et al. “Obstetrician-gynaecologists beliefs about when pregnancy begins”, American Journal of Obstetrics and Gynaecology,. 2012; 206(2):132.e1-132.e7.
[3] Lina M. Neriander, William M. Callaghan et al. “Short Inter-Pregnancy Interval’s Associated with preterm Birth in US Adolescents”. Maternal Child Health Journal. 2017; 19(4):850-58.
[4] Trivedi P, Saxena D et al. “A Cohort Study on Risk Factors For Preterm Birth in Rural Gujarat,”Indian Journal Of Public Health, 2018; 62(2):112-116.
[5] Lema Desalegn Hailu et al. “Determinanats of Low Birth Weight among Deliveries at a Referral Hospitalin Northern Ethiopia”, International Journal of Bio Med Research, 2018; 10(1):8.
[6] Mahajan A, Magon S. “Study of risk factors for preterm births in a teaching hospital”. International Journal of Medical Sciences. 2017; 6(1):1407-12.
[7] Min Jiang, Miskatul Mustafa Mishu et al. “A Case Control Study of Risk Factors and Neonatal Outcomes of Preterm Birth”, Taiwanese Journal of Obstetrics and Gynaecology. 2018; 57(1):814-17.
[8] Chytra R. Rao, Parvathi Bhat, et al. “A Case Control Study On Risk Factors for Preterm Deliveries in a secondary care hospital, Southern India”. ISRN Obstetrics and Gynaecology.2014; 1-5. Available from: https://doi.org/10.1155/2014/935982.
[9] Jamal S, Srivastava R, et al. “A Retrospective Analytical Study of the Epidemiology and Causes of Etiology”. International Journal of Reproduction, Contraception, Obstetrics and Gynaecology.2017; 6(12):5453-57.
[10] Dhingra S, Shukla B, et al. “Preterm Labour: A Study of Etiological Risk Factors and Perinatal Outcome”. International Journal of Advanced Research. 2017; 5(1):703-7.
[11] Murad M, Arbabet M, al. “Study of risk factors affecting and causing preterm birth”. Journal of Entomology and Zoology Studies.2017; 5(2):406-9.
[12] Garg S, Kaur T, et al. “A study of etiology and outcome of preterm birth at a tertiary care centre”. International Journal of Reproduction, Contraception, Obstetrics and Gynaecology.2017; 6(1):4481-91.
[13] Koucky M, Germanova A, Hájek Z, Parizek A, et al.Pathophysiology of Preterm Labour. Research Gate Journal. Prague medical report. 2009; 110(1):13–24.
[14] Robert E Garfield, Miha Lucovnik et al. “Diagnosis and Effective Management of Preterm Labour”. MGM Journal of Medical Sciences. 2014; 1(1):22-37.
[15] Rundell K, Pancha B,. “Preterm Labour: Prevention and Management”. American Family Physician.2017; 95(6):367-68.
[16] Howson C.P. MV Kinney et al. March of Dimes. save the children. WHO; Born Too Soon: The global action report on prererm birth. Geneva: 2012:126.
[17] Anna Clara F. Vieira et al. “Oral, systemic and socioeconomic factors associated with preterm birth”. Journal of Women and Birth. 2018; 32(1):12-16.
[18] Vause S, Johnson T. “Management of preterm labour”. Archives of Disease in Childhood. 2019; 83(2):79-85.
[19] Radhanpuri F, Deepak A. et al. “Preterm Birth and Its Outcome”. International Journal of Reproduction, Contraception, Obstetrics and Gynaecology. 2014; 3(1):153-57.
[20] C. Oliver-Williams et al. “Previous miscarriage and the subsequent risk of preterm birth in Scotland”. BJOG. 2015; 122(11):1525-34.
[21] Baha M. Sibai MD, et al. “Pre-eclampsia Evaluation and Management of Severe Preeclampsia before 34 weeks Gestation”. American Journal of Obstetrics and Gynaecology. 2011; 205(3):191-98.
[22] Taneja A, Chopra I, et al. “Pregnancy Outcomes in Isolated Oligohydramnios during Second Trimester: A Case Series”. Journal of Clinical and Diagnostic Research. 2017; 11(8):1-2.
[23] Fatima M. Akinlusi, Kabiru A. Rabiu et al. “Caesarean deliver- related blood transfusion: correlates in a tertiary hospital in Southwest Nigeria”. BMC Pregnancy and childbirth. 2017; 24(18):1-9.
[24] Oscar Storms, Jose et al. “Risk Factors and Predisposing Conditions for UT”. Therapeutic Advances in Urology .2019; 11(1):19-28.
[25] N. Medley, B Poljak et al.” Clinical guidelines for prevention and management of preterm birth: a systemic review”. British Journal of Obstetrics and Gynecology. 2018; 111(10):1361-69.
[26] Lawrence Oppenheimer, MD et al. “Diagnosis and Management of Placental Previa”. Journal of Obstetrics and Gynaecology. 2017; 29(3):261-66.
[27] Sharma D, Shastri S, et al. Intrauterine Growth Restriction: Antenatal and Postnatal Aspects, Clinical Medicine Insights: Pediatrics. 2016; 10(1):67-83.
[28] David K. Turok MD et al. “Management of Gestational Diabetes Mellitus”. American Family Physician. 2003; 68(9):1767-73.
[29] Vaja P, Goyal M, et al. “A Comparative study of Two Tocolytic agents for Inhibition of Preterm”, Gujarat Medical Journal, 2014; 69(1):28-31.
[30] Rupsa C. Boelig, Eva Jiang et al. “Utilisation of progesterone and cervical length screening for prevention of recurrent preterm birth”. The Journal of Maternal-Fetal and Neonatal Medicine. 2018; 32:4146-153.
[31] Lema Desalegn Hailu et al. “Determinants of Low Birth Weight among Deliveries at a Referral Hospital in Northern Ethiopia”. International Journal of Bio Med Research. 2018; 10:8. Available from:https://doi.org/10.1155/2018/8169615.
[32] Mohammed Bahari, Jose Carlos Adlana et al. “caffeine use for apnea of prematurity in moderate and late preterm infants: A systemic review”. Journal of Clinical Neonatology. 2019; 8(3):162-65.
Statistics
105 Views | 389 Downloads
How to Cite
1.
Susheela TL, Subbiah MV, Tabasum MA, Khan PA, Kumari M, Kiranmai E. Assessment of Risk Factors and Management Associated with Preterm Deliveries and their Outcomes in Tertiary Care Teaching Hospital. JDDT [Internet]. 20Feb.2021 [cited 22Sep.2021];11(1-s):102-7. Available from: https://jddtonline.info/index.php/jddt/article/view/4556