Phytoconstituents and antioxidant Activity of extracts of Glycine Max Seeds

  • Jeevan Menaria Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India
  • Jai Singh Vaghela Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India
  • Piyush Agarwal Geetanjali Institute of Pharmacy, Udaipur Rajasthan, India
  • S.L. Singune Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India
  • Ashok Choudhary S.N. Medical College Jodhpur, Rajasthan, India

Abstract

Glycine max is a medicinal and economical plant, belonging to the genus fabacea widely used in Mediterranean countries. In this study, we have evaluated the phytochemical constituents and its antioxidant i.e. DPPH, Hydrogen Peroxide, Reducing Peroxide, total polyphenols and flavonoids contents of methanolic and aqueous extracts of seeds. The total polyphenols content of the methanolic extract was 769 and aq 1139 mg/ml. μg GAE/ mg extract and flavonoids was 107, 120 mg/ml. In the DPPH assay, Aq extract showed the higher scavenging capacity (IC50 followed by aqueous extract with IC50 value 69.17 mg/ml and  methanolic extract 4.17 mg/ml.


Keywords: Glycine, Phytoconstituents, IC50, DPPH

Keywords: Glycine, Phytoconstituents, IC50, DPPH

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Author Biographies

Jeevan Menaria, Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India

Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India

Jai Singh Vaghela, Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India

Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India

Piyush Agarwal, Geetanjali Institute of Pharmacy, Udaipur Rajasthan, India

Geetanjali Institute of Pharmacy, Udaipur Rajasthan, India

S.L. Singune, Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India

Bhupal Nobles College of Pharmacy, B.N. University Udaipur, Rajasthan, India

Ashok Choudhary, S.N. Medical College Jodhpur, Rajasthan, India

S.N. Medical College Jodhpur, Rajasthan, India

References

1. Bhuvaneswari P. Antioxidants in Oral Healthcare. J Pharm Sci Res. 2014; 6:206-9.
2. Milbury PE, Reicher AC. Understanding the oxidant controversy scrutinizing the fountain of youth. 1st ed. Westport, Praeger Publishers; 2008.
3. Valento P, Fernandes E, Carvalho F, Andrade PB, Seabra RM, Bastos ML. Antioxidant activity of Hypericum androsaemum Infusion: Scavenging Activity against Superoxide Radical, Hydroxyl Radical and Hypochlorous Acid. Biol. Pharm. Bull. 2002; 25:1320-1323.
4. Gulcin I, Oktay M, Kirecci E, Kufrevioglu OI.. Screening of antioxidant and antimicrobial activities of anise (Pimpinella anisum L.) seed extracts. Food Chem. 2003; 83:371–382.
5. Kourounakis AP, Galanakis D, and Tsiakitzis K. Synthesis and pharmacological evaluation of novel derivatives of antiinflammatory drugs with increased antioxidant and antiinflammatory activities. Drug Dev Res. 1999 47:9-16.
6. Gulcin I, Buyukokuroglu ME, Oktay M and Kufrevioglu IO. Antioxidant and analgesic activities of turpentine of Pinus nigra Arn. Subsp. Pallsiana (Lamb). Holmboe J Ethnopharmacol. 2003; 86:51-58.
7. Jeong SM, Kim SY, Kim DR, Nam KC, Ahn DU and Lee SC. Effect of seed roasting conditions on the antioxidant activity of defatted sesame meal extracts. Food Chem. Toxicol. 2004; 69:377–381.
8. Kanchana1 P, Lakshmi Santha M, Dilip Raj K. A Review on glycine max (l.) merr. (soybean). World journal of pharmacy and pharmaceutical Sciences. 2016; 5(1).
9. Shurtleff, W. and Aoyagi A. The Soybean Plant: Botany, Nomenclature, Taxonomy, Domestication and Dissemination. Soy info Center. california, 2007; 40.
10. Mercer-Quarshie, H. and Nsowah GF. Soybean in Ghana. In D. K. Whigham ed. Soybean production, protection and utilization. INSOY series, 1975; 2000–7.
11. Thomas J, Mary Varghese EJ. Antidiabetic and Antihyperlipidemic Activity of the Extracts of the Seeds of Glycine max (L) in Streptozotocin Induced Diabetic Mice. Drug Invent Today., 2012.
12. Jain R, Jain SK. Total phenolic content and antioxidant activities of some selected anticancer medicinal plant from Chhattisgarh state, India. Pharmacology online, 2011; 2:755-762.
13. Singh H. Importance of local names some useful plants in Ethnobotanical study.indian Journal of traditional knowledge. April 2008; 7 (2): pp 365 – 370.
14. Ishimaru K, Omoto T, Asai I, Ezaki K, Shimomura K: Taxifolin 3-arabinoside from Fragaria Phytochemistry 1995; 40:345-347.
15. Kanodia L, Borgohain M, Das S. Effect of fruit extract of Fragaria vesca L. on experimentally induced inflammatory bowel disease in albino rats. Indian J Pharmacol. Feb 2011; 43(1):18–21.
16. Kamboj VP, Herbal medicine, current science2000; 78(1):258 -264.
17. Nikolaeva-Glomb L, Mukova L, Nikolova N, Badjakov I, Dincheva I, Kondakova V, Doumanova L, Galabov AS. In vitro antiviral activity of a series of wild berry fruit extracts against representatives of Picorna, Orthomyxo- and Paramyxoviridae. Nat Prod Commun. 2014; 9(1):51-4.
18. Jyoti Parmar, Priyanka Sharma, Preeti Verma, Priyanka Sharma, Goyal. Chemopreventive Action of Syzygium cumini on DMBA induced Skin Papillomagenesis in Mice. Asian Pacific Journal of Cancer Prevention 2010; 2:148-153.
19. Vundac, V.B., Brantner, A.H. & Plazibat, R. Content of polyphenolic constituents and antioxidant activity of some stachys taxa. Food chemistry 2007; 104:1277- 1281.
20. Aaby K, Ekeberg D, Skrede G: Characterization of phenolic compounds in strawberry Fruits by different HPLC detectors and contribution of individual compounds to total antioxidant capacity J. Agric Food Chem 2007; 55:4395-4406.
21. Gulcin J, Elicis R, Gepdiremen A, Boyer L. Antioxidant activity of lignans from fringe free (chinanthus viginicuus L.). European food research Technol 2006; 223:759-767.
21. Rathee, J.S., Hassarajani, S.A. and Chattopadhyay, S.,Liang. antioxidant activity of Nyctanthes arbor – tristis leaf extract. Food chemistry 2007; 03:1350 – 1357.
22. Kuti J.O. Antioxidant compounds from four opuntia cactus pear fruit varieties. Food chemistry 2004; 85:527- 533.
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1.
Menaria J, Vaghela JS, Agarwal P, Singune S, Choudhary A. Phytoconstituents and antioxidant Activity of extracts of Glycine Max Seeds. JDDT [Internet]. 15Jan.2020 [cited 14Apr.2024];10(1):178-83. Available from: https://jddtonline.info/index.php/jddt/article/view/4329