On Buprenorphine Implants: Should It Be Widely Used For Medically Assisted Treatment?
Abstract
Buprenorphine implants are recognized as one of the routes to administer Medically Assisted Treatment (MAT). However, the use of these implants is far less compared to oral medications in battling substance abuse. This article explores the likely reasons why buprenorphine implants are not as commonly recommended, and whether it is a feasible option to consider it a mainstream type of treatment.
DOI
https://doi.org/10.22270/jddt.v10i4-s.4257References
McKeganey N, Russell C, Cockayne L. Medically assisted recovery from opiate dependence within the context of the UK drug strategy: Methadone and Suboxone (buprenorphine-naloxone) patients compared. Journal of substance abuse treatment. 2013 Jan 1;44(1):97-102. Retrieved from https://www.sciencedirect.com/science/article/pii/S0740547212000803
US Food and Drug Administration. FDA approves the first buprenorphine implant for the treatment of opioid dependence. News Release. Silver Spring, MD: FDA. 2016 May 26. Retrieved from https://www.fda.gov/news-events/press-announcements/fda-approves-first-buprenorphine-implant-treatment-opioid-dependence
Food and Drug Administration. Subutex and Suboxone approved to treat opiate dependence. FDA Talk Paper T02-38. Retrieved February. 2002 Oct 8;19:2003. Retrieved from https://www.naabt.org/faq_answers.cfm?ID=2
Stewart SA, Domínguez-Robles J, Donnelly RF, Larrañeta E. Implantable polymeric drug delivery devices: classification, manufacture, materials, and clinical applications. Polymers. 2018 Dec;10(12):1379. Retrieved from https://www.mdpi.com/2073-4360/10/12/1379
White J, Bell J, Saunders JB, Williamson P, Makowska M, Farquharson A, Beebe KL. Open-label dose-finding trial of buprenorphine implants (Probuphine)® for treatment of heroin dependence. Drug and alcohol dependence. 2009 Jul 1;103(1-2):37-43. Retrieved from Open-label dose-finding trial of buprenorphine implants (Probuphine)® for treatment of heroin dependence
Bell JR, Butler B, Lawrance A, Batey R, Salmelainen P. Comparing overdose mortality associated with methadone and buprenorphine treatment. Drug and alcohol dependence. 2009 Sep 1;104(1-2):73-7. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S037687160900115X
Published
Abstract Display: 382
PDF Downloads: 608 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

.