Conceptual Study on Effect of Edagajadi Yoga and Gandhapashanadi Lepa in the Management of Sidhma Kushtha W.S.R. to Pityriasis Versicolor
Abstract
Tinea versicolor is a common superficial fungal infection of the skin, prevalent in the hot and humid environment of India. It is caused by the
Malassezia species which is a dimorphic, lipophilic fungus most frequently affecting the seborrheic areas of the body like face, neck, upper back and chest. Normally 10- 15% of the general practitioner’s encounter skin disorders in their day to day practice with overall prevalence rate of 30% or more probably occurring in tropical zones. Kustha a type of skin disorder mentioned in Ayurveda is a Tridoshaja Vyadhi, where Twaka, Rakta, Mamsa and Ambu are the main Dushyas. According to Charaka, Sidhma is a Kapha Vata Pradhan Vyadhi and According to Sushruta, Sidhma is Kapha Pradhan vyadhi. Management of sidhma includes Shodhana, Shamana and Bahirparimarjana Chikitsa among them Shamana in the form of kwatha & Bahirparimarjana Chikitsa as Lepa has shown appreciable result in many previous researches. So, need of time is to go for cost effective, safe and efficient treatment of Sidhma. Although, there are many drugs available in modern medical science for the treatment of Pityriasis versicolor which is found to be effective but is unsatisfactory for long term prophylaxis, so there is need of the hour to look into the safe, efficient & satisfactory remedy which not only treat the above ailments, but also ensure reduction in the episodes of relapse of the disease. Keeping all the above points in mind Edagajadi yoga & Gandhapashanadi lepa has been selected to know its efficacy in treating Sidhma kushtha (Pityriasis versicolor). Edagajadi yoga & Gandhapashanadi lepa consists of 10 drugs with different properties which includes Edagaja, Vidanga, Haridra, Daruharidra, Amlatasa, Kushta, Pippali, Gandhak, yavkshar, sarshapa taila.
Keywords: Sidhma, Pityriasis versicolor, Edagajadi yoga, Gandhapashanadi lepa
Keywords:
Sidhma, Pityriasis versicolor, Edagajadi yoga, Gandhapashanadi lepaDOI
https://doi.org/10.22270/jddt.v10i4-s.4198References
Hay RJ, Moore MK. Mycology. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook's Textbook of Dermatology. 6th ed. Oxford: Blackwell Science; 2004; p. 31.1-101.
SILVA‐LIZAMA ED. Tinea versicolor. International journal of dermatology. 1995 Sep; 34(9):611-7.
Gupta AK, Bluhm R, Summerbell R. Pityriasis versicolor. Journal of the European Academy of Dermatology and Venereology. 2002 Jan; 16(1):19-33.
Borelli D, Jacobs PH, Nall L. Tinea versicolor: epidemiologic, clinical, and therapeutic aspects. Journal of the American Academy of Dermatology. 1991 Aug 1; 25(2):300-5.
Roberts SOB. Pityriasis versicolor. In: Verbov JL, ed. Superficial fungal infections: new clinical applications in dermatology. Lancaster: MTP Press, 1986; 47-72.
Agnivesha, Charaka, Charaka Samhita, Chikitsa Sthana 7/19, edited by Vaidya Yadavaji Trikamji Acharya Chaukhamba Surbharati Prakashana, Varanasi 2014; pg.no.252
Midgley G, Gueho E, Guillot J. Disease caused by Malassezia species. Topley and Wilson’s Microbiology and microbial infections. 1998;4: 201-11.
Klenk AS, Martin AG, HEFFERNAN M. Yeast infections: candidiasis, pityriasis versicolor. FREEDBERG, IM; EISEN, AZ; WOLFF, K.; AUSTEN, KF. 2003; p. 32-34.
Dj K. Pityriasis versicolor--modern views on etiology, pathogenesis and therapy. Srpski Arhiv za Celokupno Lekarstvo. 1992 May 1;120(5-6):184-7.
Khare C.P. (Ed.) Indian Medicinal Plants An Illustrated Dictionary Springer Science Business Media, LLC.2007; pp. 130.
Patil UK, Saraf S, Dixit VK, Hypolipidemic activity of seeds of Cassia tora Linn, J. Ethnopharmacol, 2004; 90(2-3): 249-252
Lemli J, Cuveela, J. Chromatography of anthrone glycosides of purgative drug, Planta Med., 1974; 26: p. 193 (Chemical Abstract, 1975, 82,35074X)
Maitya T.K., Mandal S.C., Saha B.P. and Pal M., Evaluation of hepatoprotective potential of Cassia tora leaf extract, Nat. Prod. Sci, 1998; 4(4): 226.
Sivasankar C, Gayathri S, Bhaskar JP, Krishnan V, Pandian SK. Evaluation of selected Indian medicinal plants for antagonistic potential against Malassezia spp. and the synergistic effect of embelin in combination with ketoconazole. Microbial pathogenesis. 2017 Sep 1; 110:66-72.
S.N. Madhavan, R. Arimboor, C. Arumughan, RP-HPLC-DAD method for the estimation of embelin as marker in Embelia ribes and its polyherbal formulations, Biomed. Chromatogr. 2011; 25 (5): p. 600-605.
S.N. Madhavan, R. Arimboor, C. Arumughan, RP-HPLC-DAD method for the estimation of embelin as marker in Embelia ribes and its polyherbal formulations, Biomed. Chromatogr. 2011; 25 (5) p. 600-605.
Toda S, Miyase T, Arich H, et al. Natural antioxidants. Antioxidative compounds isolated from rhizome of Curcuma longa L. Chem Pharmacol Bull, 1985; 33: p.1725-1728
Arora R, Basu N, Kapoor V, et al. Antiinflammatory studies on Curcuma longa (turmeric). Indian J Med Res, 1971; 59: p. 1289-1295.
Wuthi-udomlert M, Grisanapan W, Luanratana O, Caichompoo W: Antifungal activity of Curcuma longa grown in Thailand. Southeast Asian J. Trop. Med. Public Health, (2000);31: 178.
Sharma R, Sharma M. Additive and inhibitory effect of antifungal activity of Curcuma longa (Turmeric) and Zingiber officinale (Ginger) essential oils against Pityriasis versicolor infections. Journal of Medicinal Plants Research. 2011 Dec 30;5(32): p. 6987-90.
Singh I, Singh VP, Antifungal properties of aqueous and organic extracts of seed plants
against Aspergillus flavus and A. niger, Phytomorphology 2000;50: p. 151-157.
Potdar D, Hirwani RR, Dhulap S, Phyto-chemical and pharmacological applications of Berberis aristata, Fitoterapia 2012; 83: p. 817-830.
Prasad, Dr. Shyam & Kaur, Darshpreet. In Vitro Anti Acne Activity of Ethanolic Extract of Stem of Berberis aristata. International Journal of Pharmacognosy and Phytochemical Research. (2017);9:10.25258/phyto v9i2.8061
Verma H, Prasad SB, Yashwant. Herbal drug delivery system: A modern era prospective. Int J Curr Pharm Rev Res 2013;4(3):88-101.
Pandey M, Debnath M, Gupta S, Chikara SK. Phytomedicine: An ancient approach turning into future potential source of therapeutics. J Pharmacogn Phytother 2011;3(1):113-7. 8.
Yarnell E, Abascal K. Herbal medicine for acne vulgaris. Altern Complement Ther 2006;12(6):303-9. 6.
Navodi WL, Ediriweera E.R.H.S.S., Ajith Kumara H.B.K. Sri Lankan traditional Virechana Karma with Ehela Peni (Cassia fistula) and application of Kaluwala Alepa (Alpinia malaccensis) in treatment of Sidhma Kushta (Pityriasis versicolor) -A case study. Int. J AYUSH CaRe. 2017;1(2): 1-6
Dahanukar SA, Kulkarni RA, Rege NN. Pharmacology of medicinal plants and natural products. Indian J Pharmacol. 2000;32: S81–118
Prashanth KV, Chauhan NS, Padh H, Rajani M. Search for antibacterial antifungal agents from selected Indian medicinal plants. J Ethnopharmacol. 2006; 107:182–8
Lorenzini R, Mercantini R, and De Bernardis F. In vitro sensitivity of Malassezia spp. to various antimycotics. Drugs Exp Clin Res, 1985; 11(6):393-5.
Bhalodia NR, Nariya PB, Acharya RN, Shukla VJ. In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts, AYU 2012;33(1): 123-129.
Bhalodia NR, Shukla VJ. Antibacterial and antifungal activities from root extracts of Cassia fistula l.: An ethnomedicinal plant. Journal of Advanced Pharmaceutical Technology & Research. 2011; Apr;2(2):104-109. DOI: 10.4103/2231-4040.82956.
Madhavi, M. & Mallika, G. & Lokanath, N. & Vishnu, M.N. & Chetty, C. & Sheikuduman, Mohamed Saleem. A review on phytochemical and pharmacological aspects of Saussurea lappa. Int. J. Life Sci. Med. Res (2012); 2. 24-31.
Pandey, M.M., Singh, M., Rastogi, S. and Rawat, A.K.S.: Antimicrobial activity of methanolic extract and oil of Saus-surea costus roots. Nigerian J. Nat. Prod. Med. (2008); 12:95-98.
Gomare, Komal & Nagime, Pooja & Mishra, Debendranath. Study of Inhibitory Effect of Plant Extracts on Lipolytic Enzymes Secreted By Malassezia furfur. IOSR Journal of Pharmacy and Biological Sciences. (2018); 13. 17-24.
Gupta, Aditya K., and Karyn Nicol. "The Use of Sulfur in Dermatology." Journal of Drugs in Dermatology : JDD, vol. 3, no. 4, 2004, pp. 427-31.
Sulfur and sulfur nanoparticles as potential antimicrobials: from traditional medicine to nanomedicine.
Rai M, Ingle AP, Paralikar P Expert Rev Anti Infect Ther, 2014 ;(10):969-978,
M. N. Chatterji and R. Shinde Sulphur, Text book of Biochemistry. Jaypee Brothers Pubn , Delhi. 2nd Edn : 1995 : pg 811.
National Toxicology Program (NTP). Corrositex: An in vitro test method for assessing dermal corrosivity potential of chemicals. The results of an independent peer review evaluation. 1999;p. 127
Database on Medicinal Plants Used in Ayurveda, Published by The central council of Research in Ayurveda & Siddha, New Delhi, Year of publication, 2001,1: 8
Mejia, Beatriz & Palou, Enrique & López-Malo, Aurelio. Composition, Diffusion, and Antifungal Activity of Black Mustard (Brassica nigra) Essential Oil When Applied by Direct Addition or Vapor Phase Contact. Journal of food protection. (2015);78:p. 843-8. 10.4315/0362-028X.JFP-14-485
http://www.essential oils.co.za/essential_oils/mustard.htm#oil properties
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