ACCELERATED STABILITY STUDIES OF FLURBIPROFEN FILM COATED TABLETS OF FIVE DIFFERENT NATIONAL BRANDS IN PAKISTAN

Authors

  • Ibrahim Javed Faculty of Pharmacy, Bahauddin Zakarayia University, Multan, Pakistan.
  • Saeed ur Rasheed Nazir Faculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.
  • Nazar Muhammad Ranjha Faculty of Pharmacy, Bahauddin Zakarayia University, Multan, Pakistan.
  • Asif Massud Department of Pharmacy, Government College University, Fasialabad, Pakistan.
  • Liaqat Hussain Department of Pharmacy, Government College University, Fasialabad, Pakistan.

Abstract

Flurbiprofen is a potent non-steroidal anti-inflammatory drug, prescribed commonly for musculoskeletal and joint disorders like arthritis. It is well established that drug degradation during storage and transportation is of particular issue in tropical countries like Pakistan, having areas with temperature variations from 0oC (Muree, Islamabad, Sawat and Azad Jammu Kashmir) to 50oC (Sibi, Jackababad, Nawabshah, Larkana, Multan and Bahawalpur) and some areas with high relative humidity (Karachi). Present study was designed to evaluate five different national brands of flurbiprofen 100 mg film coated tablets by accelerated stability studies and examined for the parameters of hardness, disintegration, dissolution and assay for drug concentration in formulation after one, three and six months duration at controlled tropical conditions of temperature and relative humidity. Dosage forms of all selected national brands were found stable even after expiry date.

DOI

https://doi.org/10.22270/jddt.v3i2.402

Published

2013-03-14
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How to Cite

1.
Javed I, Nazir S ur R, Ranjha NM, Massud A, Hussain L. ACCELERATED STABILITY STUDIES OF FLURBIPROFEN FILM COATED TABLETS OF FIVE DIFFERENT NATIONAL BRANDS IN PAKISTAN. J. Drug Delivery Ther. [Internet]. 2013 Mar. 14 [cited 2025 Jul. 18];3(2). Available from: https://jddtonline.info/index.php/jddt/article/view/402

Issue

Vol. 3 No. 2 (2013): Volume 3, Issue 2, March-April, 2013

Section

Research

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How to Cite

1.
Javed I, Nazir S ur R, Ranjha NM, Massud A, Hussain L. ACCELERATED STABILITY STUDIES OF FLURBIPROFEN FILM COATED TABLETS OF FIVE DIFFERENT NATIONAL BRANDS IN PAKISTAN. J. Drug Delivery Ther. [Internet]. 2013 Mar. 14 [cited 2025 Jul. 18];3(2). Available from: https://jddtonline.info/index.php/jddt/article/view/402
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