Changes in Life Quality of Chronic Kidney Disease Patients with Hemodialysis Who Are Given Vitamin B1, B6, and B12 Parenterally
Abstract
Background: Chronic kidney disease (CKD) is a disease that causes a progressive decrease in kidney function, which can end in kidney failure disease and will have an impact on decreasing quality of life. Previous research has shown that by giving vitamins B1, B6, and B12 can improve quality of life.
Aim: To measure changes in quality of life in patients with chronic kidney disease who were given vitamins B1, B6, and B12 parenterally.
Material and Methods: This study used quasi experimental (one group pre and post test) in 117 patients who were selected in Bethesda Hospital and Panti Rapih Hospital Yogyakarta hemodialysis unit. Patients were given vitamins B Combination injections twice a week in each hemodialysis for 4 weeks. Quality of life was measured by SF-8 questionnaire on the first day of hemodialysis before given vitamins (pre-test) and on the 30th day, after eight injection of vitamins B1, B6, and B12 (post test).
Results: The mean age of observed patients were 51.58 ± 12.51 years. From 117 patients, 73 patients (62,4%) were male and 44 patients (37.6%) were female. The improvement in overall quality of life in patients was not significant (p= 0.055). Quality of life improvement was only significant in the male group (p = 0.016).
Conclusion: There was no significant difference after 4-weeks-injections of vitamins B Combination to the overall quality of life in chronic kidney disease patients undergoing hemodialysis. But there was found a significant improvement in quality of life in the male patients with chronic kidney disease who had hemodialysis.
Keywords : chronic kidney disease, quality of life, vitamins B1, B6, and B12, SF-8 questionnaire.
DOI
https://doi.org/10.22270/jddt.v10i2.3994References
Suwitra, K. Chronic Kidney Disease. In: Setiati S, Alwi I, Sudoyo AW, Simadibrata M, Setiyohadi B, Syam AF, editors. Internal Medicine Book. 6thed. Jakarta : Interna Publishing; 2014.
Roberts B, Browne J, et al. (2008) The Reability and Validity of The SF-8 With A Conflict-Affected Population in Northern Uganda. Health and QOL Outcomes; 2008. Available from : https://www.ncbi.nlm.nih.gov/pubmed/19055716
Linda, Ni Putu. Characteristics Quality of Life in Patients with Chronic Kidney Disease Undegoing Hemodialysis in Bethesda Hospital Yogyakarta. Yogyakarta : Faculty of Medicine Duta Wacana Christian University; 2017.
Gerasimoula, K., Lefkothea, L., Maria, L., Victoria, A., Paraskevi, T., & Maria, P. Quality of Life in Hemodialysis Patients. Materia socio-medica; 2015; 27(5):305-9. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26622195
Cruz, M.C., Andrade, C., Urrutia, M.I., Draibe, S., et al. Quality Of Life in Patients with Chronic Kidney Disease; 2011; 66(6):991-995.
Available from : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130152/
Tsai YC HC, et al. Quality of Life Predicts Risks of End-Stage Renal Disease and Mortality in Patients with Chronic Kidney Disease. Nephrol Dial Transplant; 2010. Available from: https://www.ncbi.nlm.nih.gov/pubmed/20037172
Sukandar, E. Nephrology Clinic. Edisi IV. Bandung: IPEDE; 2013.
Ashous, Nermeen, et al. Folic Acid and Vitamin B Complex Improves Quality of Life in Hepatitis C Infected Patients Treated with Peginterferon and Ribavirin. British Journal of Medical and Health Research; 2015. Available from :
Saifan, C., Samarneh, M., Shtaynberg, N., Nasr, R., El-Charabaty, E., El Sayegh,S. Treatment of confirmed B12 deficiency in hemodialysis patients improves Epogen® requirements. International journal of nephrology and renovascular disease; 2013; 89-93. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681404/
Miller, A.L. The Methylation, Neurotransmitter, and Antioxidant Connections Between Folate and Depression. Altern Med Rev. 2008; 13; 216-226. Available from: http://archive.foundationalmedicinereview.com/publications/13/3/216.pdf
Reynolds, E. Benefits and Risks of Folic Acid to the Nervous System. J Neurol Neurosurgery Psychiatry; 2002; 72(5):567-571. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737896/
Braga, S.F., Peixoto, S.V., Gomes, I.C., Acurcio, F.A., Andrade, E.I., Cherchiglia, M.L. Factors Associated with Health-Related Quality of Life in Elderly Patients on Hemodialysis. Rev Saude Publica; 2011; 45(6):1127-36. Available from: https://www.ncbi.nlm.nih.gov/pubmed/22124742
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