Formulation and Evaluation of Herbal Topical Gel Containing Leaves Extract of Andrographis paniculata
Abstract
Objective: The present study has been undertaken with the aim to formulate and evaluate the gel contaning leaf extract of Andrographis Paniculata.
Methodology and results: The formulation was designed by using alcoholic extract of leaves of Andrographis paniculata.The gel was prepared by using carbapol 934, triethanolamine, propylene glycol, methyl paraben, propyl paraben and required amount of distilled water. The prepared gel was evaluated for physical appearance, pH, spread ability, viscosity, extrudability, albumin denaturation assay and stability.
Conclusion: Carbopol gels with dried leaves extract of Andrographis paniculata could be prepared successfully.
Key words: Topical gel,Kalmegh, Spreadability, Albumin denaturation
Keywords:
Topical gel, Kalmegh, Spreadability, Albumin denaturationDOI
https://doi.org/10.22270/jddt.v10i1.3837References
Sharma M, Sharma RG, Sharma A. Study of physicochemical properties of drug & physiological variation in leaves of Andrographis paniculata (BURM.F.) Nees. ActaChim. Pharm. Indica 2013; 3(1):52-64.
Shobha M, Roopashree TS. Antiacne & wound healing activity of polyherbal topical gel comprising Andrographispaniculata (Burm.f.) Wall.ex nees, GlycyrrhizaglabraL, Carica papaya L. and Cucurbitapepo L. Annals of Phytomedicine 2017; 6(1):114-120.
Khandelwal KR, Sethi V Practical pharmacognosy: ISBN NO 978-81-85790-30-5 Twenty Fourth Edition Aug 2014.
Rajasekaran A, Govindarjan A, Ramasamy A. Formulation and evaluation of topical gel for the treatment of arthritis in animal model. BJPS 2016; 52.
Misal G, Dixit G and Gulkari V. Formulation &evaluation of herbal gel: Indian Journal of Natural Products and Resources 2012; 3(4)501-505.
Reddy J.S., Lobo R., Prasanthi D., Shreedhara C.S., Pai A. Investigation of Anti- Inflammatory Potentials of Terminalia tomentosa Wight & Arn. Bark-An In-Vitro approach Journal of Global Pharma Technology 2017; 9(8):1-5.
Santhosh Kumar Gupta, Amit Gupta, Dhirendra Prakash, Vedpal In-vitroAntiArthratic Activity of Ethanolic extract of CalliccarpaMacrophylla Flower Int. Res. J. Pharm. 2013; 4(3):160-162.
Somnath De, Dulal Chandra Das, Tansuri Manda, In vitro Anti-inflammatory and Anti-Diabetic activity of methanolic extract of CardantheraDifformisdruce Int. Res. J. Pharm. 2016; 7(12):56-60.
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