EVALUATION OF ANTIOXIDANTS AND MOLECULAR DOCKING STUDIES OF HELICTERES ISORA FRUIT EXTRACTS

Authors

  • Polani B Ramesh Babu Department of Bioinformatics Bharath University, Seliyur. Chennai. India
  • P Krishnamoorthy Department of Bioinformatics Bharath University, Seliyur. Chennai. India
  • N Deepthi Department of Bioinformatics Bharath University, Seliyur. Chennai. India
  • M Nissi Department of Bioinformatics Bharath University, Seliyur. Chennai. India

Abstract

The medical plants are widely used by the traditional medicinal practitioners for curing various diseases. The present study aims at evaluate the phytochemical properties and antioxidant sensing activity of the fruit Helicteres Isora. For this the fruit parts of the plant were chosen and extracts were prepared using methanol and ethanol. Phytochemical qualitative screening revealed the presence of compounds such as alkaloids, carbohydrates, glycosides, saponins, proteins, amino acids and flavonoids. The antioxidant activity of the plant extracts were performed by DPPH method.  The free radical scavenging activity was measured spectrophotometrically as maximum fading power of DPPH at 517nm. All extracts showed different level of antioxidant activity. Molecular docking studies was also done to study the mechanism of action of the active compounds present in the fruit.

Keywords: Helicteres Isora, DPPH assay, FRAP assay, Phytochemicals, Molecular docking.

DOI

https://doi.org/10.22270/jddt.v3i1.381

Published

2013-01-14
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How to Cite

1.
Babu PBR, Krishnamoorthy P, Deepthi N, Nissi M. EVALUATION OF ANTIOXIDANTS AND MOLECULAR DOCKING STUDIES OF HELICTERES ISORA FRUIT EXTRACTS. J. Drug Delivery Ther. [Internet]. 2013 Jan. 14 [cited 2026 Jan. 21];3(1). Available from: https://jddtonline.info/index.php/jddt/article/view/381

Issue

Vol. 3 No. 1 (2013): Volume 3, Issue 1, Jan-Feb, 2013

Section

Research

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How to Cite

1.
Babu PBR, Krishnamoorthy P, Deepthi N, Nissi M. EVALUATION OF ANTIOXIDANTS AND MOLECULAR DOCKING STUDIES OF HELICTERES ISORA FRUIT EXTRACTS. J. Drug Delivery Ther. [Internet]. 2013 Jan. 14 [cited 2026 Jan. 21];3(1). Available from: https://jddtonline.info/index.php/jddt/article/view/381
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