Study of Prevalence Rate, Side Effect and Co-Morbidities Associated with Current Drug Therapy in Patients Suffering with Nephrotic Syndrome
Abstract
Background: Nephrotic syndrome is a kidney disease caused by damage to the cluster of small blood vessels in the kidney. Nephrotic syndrome causes misfunctioning of the kidney that affects metabolism of the body significantly. It causes complications of blood clots, high blood cholesterol and elevated blood triglycerides, poor nutrition, high blood pressure, acute kidney failure, chronic kidney disease and various infections.
Objectives: The present investigation was objected to study prevalence rate, side effect of prescribed drugs and co-morbidity associated with current drug therapy in patient suffering with nephrotic syndrome.
Methodologies: The present observational study was conducted on 43 nephrotic syndrome patients. These patients were evaluated for effects and side effects of prescribed drugs. Co-morbidity related to drug current prescribed was assessed and prescribed drugs for co-morbidity for also assessed. Prevalence rate of nephrotic syndrome was calculated among the all investigated patients. Patients were investigated who signed consent form. Patients above 18 years of age were excluded from study.
Results: The involved 43 patients of nephrotic syndrome. These patients were prescribed with Corticosteroids (27%), Immunomodulator (8%), Immunosuppressant (5%), Diuretics (20%), ACE Inhibitors (5%), Angiotensin II receptor antagonist (5%). Co-morbidity were related to current drugs were observed and it was found that 9 (20%) patients were suffering from asthma, 3 (7%) patients were suffering epilepsy, 1 (2%) patients were suffering from inflammatory bowel disease, 5 (11%) patients were suffering from other diseases along with nephrotic syndrome. Prevalence rate of nephrotic syndrome was found 2.38% in patients.
Conclusion: The present study revealed that the current prescribed drugs for nephrotic syndrome causes side effects that are skin infection, behavioral changes, blood in urine and decreased neutrophils. And co-morbidity of asthma, epilepsy, inflammatory bowel disease and other disease were present in patients of nephrotic syndrome. 1 patient out of every 42 investigated patients was suffering from nephrotic syndrome.
Keywords: Nephrotic syndrome, corticosteroids, side effects, co-morbidity and prevalence rate.
DOI
https://doi.org/10.22270/jddt.v9i5-s.3589References
Nephrotic Syndrome in Adults". National Institute of Diabetes and Digestive and Kidney Diseases. February 2014. Retrieved 9 November 2017.
Ferri, Fred F. (2017). Ferri's Clinical Advisor 2018 E-Book: 5 Books in 1. Elsevier Health Sciences. p. 889.
Kher, Kanwal; Schnaper, H. William; Greenbaum, Larry A. (2016). Clinical Pediatric Nephrology, Third Edition. CRC Press. p. 307.
Kelly, Christopher R.; Landman, Jaime (2012). The Netter Collection of Medical Illustrations - Urinary System e-Book. Elsevier Health Sciences. p. 101.
The paper is found on this link: http://www.kidneyfund.org/kidney-disease/other-kidney-conditions/rare-diseases/nephrotic-syndrome/.
The paper is found on this link: https://www.niddk.nih.gov/health-information/kidney-disease/children/childhood-nephrotic-syndrome.
The paper is found on this link: https://www.assignmentpoint.com/science/medical/nephrotic-syndrome.html.
Harold Friedman, H (2001). "General problems". Problem-oriented Medical Diagnosis(Seventh ed.). Lippincott Williams & Wilkins. pp. 3 and 4.
Nephrotic syndrome. The Merck Manuals Online Medical Library. www.merckmanuals.com . Updated July 2013. Accessed July 7, 2014.
Bakkaloglu SA, Schaefer F. Diseases of the kidney and urinary tract in children. In: Taal MW, Chertow GM, Marsden PA, et al., eds. Brenner and Rector’s The Kidney. 9th ed. Philadelphia: Saunders; 2011: 2622–2643.
Curtis, Michael J.; Page, Clive P.; Walker, Michael J.A; Hoffman, Brian B. (1998). "Fisiopatología y enfermedades renales". Farmacología integrada. Harcourt. ISBN 8481743402.
Saz Peiro, Pablo. "El reposo prolongado" (PDF). Retrieved 8 Sep 2008.
Dietoterapia del síndrome nefrótico". Archived from the original on 2009-01-22. Retrieved 8 Sep 2008.
Lista de alimentos ricos en sodio". Retrieved 8 Sep 2008.
Fluidoterapia: tipos de expansores" (PDF). Archived from the original (PDF) on 2008-09-20. Retrieved 8 Sep 2008. Plasma expanders are natural or synthetic substances (dextran, albumin...), that are able to retain liquid in the vascular space.
Lista de alimentos ricos en proteínas". Retrieved 8 Sep 2008. Expressed as grams per 100 g of food.
Sustitución de los alimentos ricos en grasas de la dieta". Archived from the originalon February 12, 2008. Retrieved 8 Sep 2008. Organizations in the US recommend that no more than 30% of total daily calorie intake is from fats.
Martín Zurro, Armando (2005). "Hipolipemiante, diuréticos, estatina.". Compendio de atención primaria: Conceptos, organización y práctica clínica (Segunda ed.). Elsevier España. p. 794. ISBN 8481748161.
Jiménez Alonso, Juan. "Profilaxis de los fenómenos tromboembólicos" (PDF). Retrieved 2008-09-14.
Glassock RJ (August 2007). "Prophylactic anticoagulation in nephrotic syndrome: a clinical conundrum". J. Am. Soc. Nephrol. 18 (8): 2221–5. doi:10.1681/ASN.2006111300. PMID 17599972.
Rango Internacional Normalizado (INR)". Retrieved 2008-09-14.
The paper is found on this link: study.com/academy/lesson/what-is-comorbidity-definition-examples-in-psychology.html
The paper is found on this link:https://www.nimh.nih.gov/health/statistics/what-is-prevalence.html
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