Determination of Albuterol in Bulk and Dosage Form by UV-Visible Spectroscopy using Buffer-Ethanol System

Authors

  • Prashant G Phanasekar Department of Chemistry, University Teaching Department, Sri Satya Sai University of Technology & Medical Sciences, Sehore-466001
  • Pushpendra Sharma Department of Chemistry, University Teaching Department, Sri Satya Sai University of Technology & Medical Sciences, Sehore-466001

Abstract

A novel, simple, accurate and precise UV-visible spectroscopic method for determination albuterol in buffer-ethanol (1:1) system has been developed and validated. The linearity is obeyed over a concentration range of 10-100 μg/ml with correlation coefficient of 0.9989 for drug. The proposed method was validated by determining accuracy, precision and stability parameters. The method was found to be robust. The method was used successfully for the determination of albuterol in aerosol dosage form.

Keywords: Albuterol, Stress, Accuracy, Oxidation, Degradation

DOI

https://doi.org/10.22270/jddt.v9i3.2646

Author Biographies

Prashant G Phanasekar, Department of Chemistry, University Teaching Department, Sri Satya Sai University of Technology & Medical Sciences, Sehore-466001

Department of Chemistry, University Teaching Department, Sri Satya Sai University of Technology & Medical Sciences, Sehore-466001

Pushpendra Sharma, Department of Chemistry, University Teaching Department, Sri Satya Sai University of Technology & Medical Sciences, Sehore-466001

Department of Chemistry, University Teaching Department, Sri Satya Sai University of Technology & Medical Sciences, Sehore-466001

Published

2019-05-15
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How to Cite

1.
Phanasekar PG, Sharma P. Determination of Albuterol in Bulk and Dosage Form by UV-Visible Spectroscopy using Buffer-Ethanol System. J. Drug Delivery Ther. [Internet]. 2019 May 15 [cited 2026 Jan. 15];9(3):246-8. Available from: https://jddtonline.info/index.php/jddt/article/view/2646

How to Cite

1.
Phanasekar PG, Sharma P. Determination of Albuterol in Bulk and Dosage Form by UV-Visible Spectroscopy using Buffer-Ethanol System. J. Drug Delivery Ther. [Internet]. 2019 May 15 [cited 2026 Jan. 15];9(3):246-8. Available from: https://jddtonline.info/index.php/jddt/article/view/2646