Assessment of Glycosylated hemoglobin and lipid profile among patients with skin tags in Khartoum State-Sudan
Abstract
Background: Skin tags (acrochordons) are the common small benign connective tissue tumor of the dermis that occurs in old subjects usually located on the neck and the major flexors .and the aim of this study to estimate the prevalence of Diabetes Mellitus and dyslipidemia among patients with Skin Tags in Khartoum state.
Material and Methods: This is descriptive case control study and was conducted during the period from March to July 2018. In this study 50 [28 (56%) male and 22 (54%) female] patients with skin tags and 20 [11 (55%) male and 9 (45%) female] healthy individual are randomly selected, blood samples were collected after fulfillment of questionnaire, fasting venous blood collected in fluoride oxalate container for fasting glucose, cholesterol and triglycerides and 2.5ml venous blood in EDTA for HbA1c, and were analysis by spectrophotometer for glucose cholesterol and triglycerides and ichroma for HbA1c,obtained results were analyzed statistically by using SPSS.
Results: The mean of fasting blood glucose, HbA1c, cholesterol and triglycerides of case is (111mg.dl, 5.6 %, 205mg.dl, 160mg.dl) respectively. And the mean of fasting blood glucose, HbA1c, cholesterol and triglycerides of healthy individual is (86mg.dl, 5.0%, 149mg.dl, 170mg.dl) respectively. 62.2% of male has (1-10 ST), 38.5% of male has (11-20 ST) and 37.8% of female has (1-10 ST) ,61.5% has 11-20 ST. case aged 20-40 years (48.6% has 1-10 ST and 15.4% has 11-20 ST ), case aged 41-80 years (51.4% has 1-10 ST and 84.6% has 11-20 ST).
Conclusion: There was significant correlation between number of skin tags and mean levels of fasting blood glucose, HbA1c, and fasting serum cholesterol levels, no significant correlation between gender and number of ST, significant correlation between age and number of ST.
Keywords: Skin Tags, Fasting Blood Glucose, Hba1c, Cholesterol, Triglycerides, Sudanese
DOI
https://doi.org/10.22270/jddt.v9i2-s.2582References
Frank H. Netter Brgan E. Anderson. Th Netter. Collection of Medical illustranation, Integumentary system. 2nd ed. Philadelphia AP. 19103 -2899.
Allegue F, Fachal C, Pérez- Pérez P. Friction induced skin tags. Dermatol Online J. 2008; 14:18.
Chiritscu E, Malonly E, Achrochndrons as apreseating sign of Nevoid basal cell carcinoma syndromes. J AM Acad Dermal, 2001; 44:789-794.
Tamega Ade A, Aranha AM, Guiotoku MM, Moit LD and Moit Association between skin tags and insulin resistance. An Bras Dermatol, 2010; 8(1)5:25-31.
Hidalgo G. Dermatological complications of obesity. Am J ClinDermatol., 2008; 14:18.
Ginarte M, Garcia-Caballero T, Fernandez-Redondo V, Beiras A, Toribio J. Expression of growth hormone receptor in benign and malignant cutaneous proliferative Khartoum entities. J CutanPathol. 2000; 27:276–282.
Sari RS, Oseisy. Leptinsingnaling. PhysiolBehav, 2004; 81:223-241.
Thomas J. Zuber, E. J. Mayeaux JR. Atlas of primary care procedures.
Agarwal JK, Nigam PK Acrochordon: a cutaneous sign of carbohydrate intolerance. Australas J Dermatol, 1987; 28(3):132–133. 530 Walnut street, Philadelphia, PA 19106 USA. 2004; 104.
Frank H. Netter, Bryan E. Anderson. The Netter Collection of Medical illustrations, Integumentary system. 2nd ed. Philadelphia PA. 19103.2899. 2012; p.14 33.
ThomasJ.Zuber, E.J.Mayeaux JR. Atlas of primary care procedures. 530 Walnut street,Philadelphia, PA19106 USA. 2004;p104
Thappa DM. Skin tags as markers of diabetes mellitus: an epidemiological study in India. J Dermatol. 1995; 22(10):729-31.
S. Demir,Y. Demir. Acrochordon and impaired carbohydrate metabolism. ActaDiabetologica. June 2002; 39(2):57-59.
AbbasRasi MD, RaziehSoltani-Arabshahi MD, Nasim Shahbazi MD Skin tag as a cutaneous marker for impaired carbohydrate metabolism: a case–control study. International Journal of Dermatology. 2007; 46(11):1155–1159.
Sudy E, Urbina F, Maliqueo M, Sir T. Screening of glucose/insulin metabolic alterations in men with multiple skin tags on the neck .J DtschDermatolGes. 2008; 6(10):852-5, 852-6. doi: 10.1111/j.1610-0387.2008.06720.x. Epub 2008 Apr 4.
Department of Chemical Pathology, Guy’s, St Thomas’s, University Lewisham Hospital, London SE13 6LH, UK
Rasi A, Faghihi A, Rahmanzadeh Y, Hassannejad H. A comparison study of lipid profile levels between skin tags affected people and normal population in Tehran, Iran. Adv Biomed Res 2014; 3:109
Published
Abstract Display: 548 
PDF Downloads: 471 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.