MICROEMULSION SYSTEM IN ROLE OF EXPEDIENT VEHICLE FOR DERMAL APPLICATION

Abstract

Abstract:

Ever since the discovery of microemulsions, they have attained increasing impact in the field of both research and industry. Industrial applications of microemulsions have escalated in the last 40 years following an increased understanding of formation, stability and the role of surfactant molecular architecture. For the reason of having diverse advantages such as thermodynamic stability, increased solubility, simplistic method of preparation and low cost, these have been explored. In recent times investigation has been spurted in direction of microemulsions for transdermal drug delivery as very low surface tension associated with massive increase in interfacial area persuades drug permeation across the skin. The basic components of microemulsion are oils, surfactants and cosurfactants. The transdermal drug delivery prospective of microemulsion is basically dependant on two factors, one is applied components and the other is internal structure of the phases. The present article confronts microemulsions system as dermal drug delivery carrier highlighting the assortment of components which will augment the drug permeation across the skin.

Keywords: Microemulsions, permeation, transdermal, oils, surfactants