EVALUATION OF SAFETY & ANTI-UROLITHIATIC PROPERTY OF VARIOUS POLYHERBAL FORMULATIONS USING ETHYLENE GLYCOL-AMMONIUM CHLORIDE & POTASSIUM OXONATE INDUCED UROLITHIASIS IN RATS & MICE RESPECTIVELY

Authors

  • Rishabh Vaishnav S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India
  • Smit Patel S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India
  • Nilesh Patel S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India

Abstract

The aim of present work was to evaluate safety & anti- urolithiatic property of various polyherbal formulations using ethylene glycol-ammonium chloride & potassium oxonate induced urolithiasis in rats & mice and to evaluate and to evaluate effect of poly herbal formulation on oxidative stress, i.e. SOD, catalase, LPO and to evaluate of poly herbal formulation on physical parameter i.e. body weight, urine PH, urine volume

DOI

https://doi.org/10.22270/jddt.v7i7.1639

Author Biographies

Rishabh Vaishnav, S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India

S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India

Smit Patel, S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India

S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India

Nilesh Patel, S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India

S. K. Patel College of Pharmaceutical Education and Research, Ganpat University, Vidhyanagar-384012, India

References

Sinha AK, Coloimetric assay of catalase, Ana Biochem, 1972, 47, 389-395.

Lowry OH, Rosebrough NJ, Farr AL, Randall RJ, Protein measurement with the Folin phenol reagent, JBC, 1951, 193, 265-275.

Adhirai M, Selvam R, Effect of cyclosporine A on tissue lipid peroxidation and membrane bound ATPase in hyperoxaluric rat and the protection by vitamin E treatment, JJMSB, 1993, 50, 9.

Adhirai M, Selvam R, Protection of cyclosporine A induced biochemical changes by vitamin E pre-treatment in hyperoxaluric rat kidney, JNB, 1997, 1197,8,32.

Adhirai M, Selvam R, Effect of cyclosporine on liver antioxidants and the protective role of vitamin E in hyperoxaluria in rats, JPP, 1998, 50, 501.

Published

2017-12-22
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How to Cite

1.
Vaishnav R, Patel S, Patel N. EVALUATION OF SAFETY & ANTI-UROLITHIATIC PROPERTY OF VARIOUS POLYHERBAL FORMULATIONS USING ETHYLENE GLYCOL-AMMONIUM CHLORIDE & POTASSIUM OXONATE INDUCED UROLITHIASIS IN RATS & MICE RESPECTIVELY. J. Drug Delivery Ther. [Internet]. 2017 Dec. 22 [cited 2026 Jan. 21];7(7):208-10. Available from: https://jddtonline.info/index.php/jddt/article/view/1639

How to Cite

1.
Vaishnav R, Patel S, Patel N. EVALUATION OF SAFETY & ANTI-UROLITHIATIC PROPERTY OF VARIOUS POLYHERBAL FORMULATIONS USING ETHYLENE GLYCOL-AMMONIUM CHLORIDE & POTASSIUM OXONATE INDUCED UROLITHIASIS IN RATS & MICE RESPECTIVELY. J. Drug Delivery Ther. [Internet]. 2017 Dec. 22 [cited 2026 Jan. 21];7(7):208-10. Available from: https://jddtonline.info/index.php/jddt/article/view/1639