NOVEL FORMULATION STRATEGIES FOR INSULIN DELIVERY

Authors

  • Dhruvkumar Soni Graduate Research Assistant, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68105

Abstract

Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Successful oral insulin delivery involves overcoming the enzymatic and physical barriers. Several companies across the globe are developing oral insulin based on different technology platforms. Insulin has been encapsulated in nanoparticles by mucoadhesive polymers such as chitosan, poly (lacticco-glycolic acid) (PLGA), and alginate which prevent enzymatic degradation and allow absorption across the epithelial layer in Peyer’s patches.

Keywords: Novel Formulation Strategies, Insulin, hyperglycemia, Nanosphere-based oral insulin delivery

DOI

https://doi.org/10.22270/jddt.v7i2.1396

Author Biography

Dhruvkumar Soni, Graduate Research Assistant, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68105

Graduate Research Assistant, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68105

Published

2017-03-15
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How to Cite

1.
Soni D. NOVEL FORMULATION STRATEGIES FOR INSULIN DELIVERY. J. Drug Delivery Ther. [Internet]. 2017 Mar. 15 [cited 2026 Jan. 20];7(2):119-27. Available from: https://jddtonline.info/index.php/jddt/article/view/1396

Issue

Vol. 7 No. 2 (2017): Vol 7, Issue 2, March-April 2017

Section

Review

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How to Cite

1.
Soni D. NOVEL FORMULATION STRATEGIES FOR INSULIN DELIVERY. J. Drug Delivery Ther. [Internet]. 2017 Mar. 15 [cited 2026 Jan. 20];7(2):119-27. Available from: https://jddtonline.info/index.php/jddt/article/view/1396
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