Prescription Pattern Analysis of Type II Diabetes Mellitus Inpatients and Associated Co-Morbidities

  • Purnima Ashok Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India
  • Vijesh Thollur Subrahmanian Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India
  • Rinju Raj Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India
  • Rahul Rajendra Babu Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India
  • Ramshad T. P. Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India
  • Kevin L. Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Abstract

Background: The present study was planned to assess the prescription pattern analysis of Type II Diabetes Mellitus and associated co-morbidities. As per WHO, the worldwide prevalence of DM will reach 366 million by 2030. Evaluating drug prescription pattern is a major aspect of patient care, which is used as a measure of the quality of care provided. Objectives: Primary objectives of the study were to highlight the current prescription pattern trends in patients having diabetes mellitus with or without other co-morbid conditions, to ensure safety and rational use of prescribed regimen. And the secondary objectives of the study were to analyse the demographic information of the enrolled patients and also to identify and analyse the prescriptions with polypharmacy. Materials and Methods: A prospective observational study was conducted to analyse the prescribing pattern of anti-diabetic drugs. The study incorporated 100 Type II DM inpatients having comorbid conditions. The study has been conducted with the help of WHO prescribing indicator scale. It is used to analyse drug class, generic and branded drugs, fixed dose combination and dosage form. Patient data was collected and medical data records were analysed daily till discharge from hospital. Results: It was found that most of the drugs have been prescribed are purely from Karnataka Essential Medicine list (KEML). And percentages of medicines prescribed on their generic name were 76%. About 51% of patients were treated only with oral hypoglycemic agents. Whereas, 38% were treated with Insulin and 11% were treated with both oral hypoglycemic agents and Insulin. Conclusion: Improved rational use of prescription by using Essential Medicine List (EML).And also ensured the appropriateness of prescription by using WHO scale. Several Adverse Drug Reactions (ADR)have been reported and which leads to improved  prescription pattern.


Keywords: Type II Diabetes Mellitus, Prescribing Indicator, Co-Morbidities.

Keywords: Type II Diabetes Mellitus, Prescribing Indicator, Co-Morbidities

Downloads

Download data is not yet available.

Author Biographies

Purnima Ashok, Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Vijesh Thollur Subrahmanian, Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Rinju Raj, Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Rahul Rajendra Babu, Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Ramshad T. P., Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Kevin L., Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

Department of Pharmacy Practice, K.L.E College of Pharmacy, Bengaluru-10, Karnataka, India

References

1. American Diabetes Association. Standards of medical care in Diabetes-2016 position statement Diabetes care; 2013; S11-S66,5-6.
2. Maitra A , Abbas A K, Kumar V, Fausto N, The Endocrine system. In: Pathologic basis of disease. 2005; 1156-1226.
3. Mahmood M, Reddy RC. Prescription Pattern Analysis of Antidiabetic Drug in Diabetes Mellitus and Associated Co-morbidities: Clin. Invest.(Lond.); 2017; 8(1);5-12.
4. Anastasios Tentolouris, Ioanna Eleftheriadou, Kostas Athanasakis, John Kyriopoulos, Diamantis I. Tsilimigras, Pinelopi Grigoropoulou, John Doupis, Prevalence of diabetes mellitus as well as cardiac and other main comorbidities in a representative sample of the adult Greek population in comparison with general population.2018;1-8.
5. Rashid M, Anandhasayanam KM, Kannan S. Prevalence of co-morbidities in Type 2 Diabetes Mellitus Patients,The Awareness Level and the Impact of Pharmacist’s Patient Education Program.2015; 4(5);11-20.
6. Campbell R.K. Type II diabetes: where we are today. An overview of disease burden,current treatments and treatment strategies. JLM Pharmacist Assoc.2009;49(suppl):S3-S9;7-14.
7. Fenstei A R, The pre-therapeutic classification of co-morbidity in chronic disease. Jchron Dis.1970; 23:455-468.
8. Lechauncy D. Woodard, Urech T, Landrum CR. The impact of comorbidity type on measures of quality for diabetes care. Med care. 2011; 49:605-610.
9. Rowan JA, Hagne WM, Gao W, Battin MR, Moore M P. For the Mig Trial Investigators,Metformin versus insulin for the treatment of gestational diabetes. 2008; 358-552.
10. Dipiro JT, Talbert RL, Gary CY, Matzke GR, Wells BJ, Michael P. Pharmacotherapy:A pathophysiologic approach. 2008; 1205-41.
11. Manjusha S, Amit M, Ronak S, A study on prescribing pattern and potential drug-drug interaction in Type 2 diabetic mellitus inpatients. 2013; 1-2.
12. Kevin M Pantalone, Todd M Hobbs,Brian J Wells.BMJ Open Diabetes Research And Care,Clinical characteristics, complications, comorbidities and treatment patterns among patients with Type 2 diabetes mellitus in a large integrated health system. 2015; 5-6.
Statistics
30 Views | 22 Downloads
How to Cite
1.
Ashok P, Subrahmanian VT, Raj R, Babu RR, P. RT, L. K. Prescription Pattern Analysis of Type II Diabetes Mellitus Inpatients and Associated Co-Morbidities. JDDT [Internet]. 15May2020 [cited 1Jun.2020];10(3):42-7. Available from: http://jddtonline.info/index.php/jddt/article/view/3977