Epidemioclinical profile and management of post thrombotic syndrome in Antananarivo

  • TSIRIMALALA Rajaobelison Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar
  • ZAKARIMANANA LUCAS Randimbinirina Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar
  • RNAL Rakotorahalahy Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar
  • AML Ravalisoa Department of surgery, Faculty of Medicine Antananarivo, University of Antananarivo, 101, Madagascar
  • AJC Rakotoarisoa Department of surgery, Faculty of Medicine Antananarivo, University of Antananarivo, 101, Madagascar

Abstract

Introduction: The post-thrombotic syndrome (PTS) is the most complication of deep vein thrombosis who deserves an early management. The aim of this study was to determine the epidemio-clinical profile and the management of PTS.


Methods: This was a retrospective and descriptive study for a period of 6 years from January 2013 to December 2018, performed at the Cardiovascular Surgery Unit in JRA Teaching Hospital Antananarivo, including all patients who presented post-thrombotic syndrome after an acute episode of deep venous thrombosis.


Results: 106 patients were recorded among 315 patients who presented an episode of DVT (33.65%) and 14110 patients admitted in this period (0.75%). The average age was 46.18 years old. There were 30 males (28.30%) and 76 female (71.69%). The most important risk factors of PTS were previous history of varicose veins (50%), sedentary lifestyle (45.28%), insufficiency of anticoagulant therapy (68.86%) and proximal DVT (47.16%). Delayed of diagnosis were greater than or equal to 2 years after an acute DVT in 86 patients (81.13%). The most clinical signs were edema (56.60%) and varicose veins (54.71%). According the Villalta’s score, PTS were mild in 48 patients (45.28%), moderate in 47 patients (44.33%) and severe in 11 patients (10.37%). Management was lifestyles change (45.28%), compression stockings (100%), anticoagulant therapy (100%) and surgical treatment (65.09%).


Conclusion: The frequency of PTS was 33.65% in our study. PTS reduces quality of life of patients, but it can be avoided if the treatments of DVT are adapted.


Keywords: Deep vein thrombosis, Post-thrombotic syndrome, Epidemiology, Management

Keywords: Deep vein thrombosis, Post-thrombotic syndrome, Epidemiology, Management

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Author Biographies

TSIRIMALALA Rajaobelison, Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar

Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar

ZAKARIMANANA LUCAS Randimbinirina, Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar

Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar

RNAL Rakotorahalahy, Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar

Department of Surgery, Faculty of Medicine Antananarivo, Antananarivo, 101, Madagascar

AML Ravalisoa, Department of surgery, Faculty of Medicine Antananarivo, University of Antananarivo, 101, Madagascar

Department of surgery, Faculty of Medicine Antananarivo, University of Antananarivo, 101, Madagascar

AJC Rakotoarisoa, Department of surgery, Faculty of Medicine Antananarivo, University of Antananarivo, 101, Madagascar

Department of surgery, Faculty of Medicine Antananarivo, University of Antananarivo, 101, Madagascar

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Rajaobelison T, Randimbinirina Z, Rakotorahalahy R, Ravalisoa A, Rakotoarisoa A. Epidemioclinical profile and management of post thrombotic syndrome in Antananarivo. JDDT [Internet]. 15Dec.2020 [cited 21Jan.2021];10(6-s):16-1. Available from: http://jddtonline.info/index.php/jddt/article/view/4420