Comparative Biological Activity Profile of Nava (Freshly Collected) and Purana (Old) Dhanyaka (Coriandrum sativum Linn.) through Gas Chromatography and In-Vitro Anti-Microbial Study
Introduction: Dhanyaka(Coriandrum sativum Linn.) belonging to family Apiaceae is one such common aromatic edible herb, the fruits of which are used as carminative, antimicrobial and cooling. Classical texts of Ayurveda advocate these fruits to be used in old condition. With this background, a study was done to compare biological activity profile of Nava and Purana Dhanyaka(Coriandrum sativum Linn.) through, Gas chromatography and in-vitro anti-microbial activity. Materials and methods: Fresh fruits of Dhanyaka(Coriandrum sativum Linn.) were collected from Rona, Gadag district and authenticated. The fresh fruits named as S1 with which essential oil extracted using clevengers apparatus. Few fruits were kept in an air tight container and stored for one year, and at the end of a year named as sample(S2), essential oil extracted and stored. Both samples were subjected for GC and in-vitro antimicrobial activity. Results and Discussion: The Essential oil of Nava Dhanyaka(S1) included 17 identified compounds which was dominated by monoterpenes and sesquiterpene; whereas S2 showed 6 identified compounds in which 3 constituents isoborneol, citronellyl acetate and geraniol were new findings. In-vitro anti-microbial study of essential oil extract showed that Purana Dhanyaka(S2) had better efficacy with respect to the standard against the strain Escherichia coli and Candida albicans; whereas that of Nava Dhanyaka(S1) against only one bacterial strain ie., Streptococcus pyogens. Conclusion: Preservation of Dhanyaka(Coriandrum sativum Linn.) showed biological changes in terms of antimicrobial activity compared to fresh sample.
Key words: Dhanyaka, Coriandrum sativum Linn., Gas chromatography, In-vitro antimicrobial study)
2. Nadakarni KM., Indian Material Medica Vol-I, Dehradun; International book Distributor: 2006, p395
3. Anonymous. The wealth of India, A dictionary of Indian raw materials & industrial products Vol 2, Newdelhi: Council of scientific & industrial research: 2009 P.270- 275
4. Murthy Srikantha KR, Sarangadhara Samhita, Chaukambha Orientalia, 1997, Varanasi, p7-8
5. Sharma Rakesh K, Arora Rajesh; Herbal Drugs–A twenty first century perspective; New Delhi: Jaypee Brothers Medical Publishers, 2006p488-89
6. Evans WC., Trease and Evan’s Pharmacognosy, 15th ed. London: WB Saunders Ltd: 2002; p45- 150
7. Reneta nurzynska- Wierdak; Essentail oil composition of the coriander (Coriandrum sativum L.) herb depending on the development stage; Acta agrobotanica; 2013; 66(1):53-60.
8. Nicholes J. Sadgrove, Graham Lloyd Jones; A contemporary introduction to essential oil; Chemistry, bioactivity and prospects for Australian agriculture; Agriculture 2015; 5:48-102.
9. Kanthal LK, Dey A, Bhojarju P; GC-MS analysis of bio-active compounds in methanolic extract of Lacctuca runcinate DC; Pharmacognosy Research; 2014; 6(1):58-61.
10. Mallya SV, Nesari T; Antibacterial activity profile and quality standards of Cymbopogon citratus Stapf- an aromatic grass used in Indian system of medicine; Journal of Ayurvedic and Herbal Medicine 2016; 2(3):63-66
11. Mukharjee PK, Quality Control of Herbal Drugs; New Delhi: Business Horizons; 2002; p68
12. Khaleel C, Tabanca N, Buchbauer G; Alpha Terpineol, a natural monoterpene; A review of its biological properties; open chemistry; 2018;16:349-361
13. Lindgren BS, Miller DR; Effect of Verbenone on fie species of Bark Beetles(Coleoptera; Scolytidae) in Lodgepole Pine Forests; Environmental Entomology, 2002 ; 31(5):759-65.
16. Chen W, Viljoen AM; Geraniol- A review of a commercially important fragrance material; South African Journal of Botany; 2010 ; 76(4):643-51
17. Leite Maria Clerya Alvino, Bezerra André Parente de Brito, de Sousa Janiere Pereira, de Oliveira Lima Edeltrudes. Investigating the antifungal activity and mechanism(s) of geraniol against Candida albicans strains. Medical Mycology; 2015; 53(3):275–284.
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