Anti-inflammatory Natural Compounds from Herbal and Marine Origin
Inflammation is pathologic condition that includes variety of diseases throughout the world. Natural products have shown their effectiveness consistently in medicinal and cosmetic field. According to World Health Organization (WHO) still about 80% of the world population rely mainly on plant-based drugs. In Ayurveda, Siddha, and Unani, utilizing a large number of medicinal plants were used for the treatment of human diseases. Herbal natural sources have ability to synthesize a wide range of phytochemical compounds which shows anti-inflammatory activity. Secondary metabolites such as alkaloids, flavonoids, saponins, coumarins, terpenoids and essential oils have clinically and experimentally shown anti-inflammory properties over the years. With the emerging developments in natural products, the marine environment has been shown to be the source of a great diversity of chemical structures with promising biological activities. Marine organisms and microorganisms have provided a large proportion of the natural anti-inflammatory products over the years. Marine sources includes bioactive compounds from micro-organisms, such as algae, bacteria, cyanobacteria, fungi and small invertebrates, such as sponges, mollusks, tunicates, echinoderms and phytoplankton’s. Algal anti-inflammatory phytochemicals have the potential to be used as therapeutics or in the synthesis of structural analogs with profound anti-inflammatory activity with reduced side effects. This review describes anti-inflammatory activity of some secondary metabolites discovered from herbal and marine sources.
Key words: Anti-inflammatory, Phytochemical, secondary metabolites, Herbal, Marine
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