A REVIEW Sublingual Immunotherapy: An Innovative Alternative for Allergies

  • Sonia T Sevlani Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India
  • Sheetal Gondkar Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India
  • Ravindranath Saudagar Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

Abstract

Sublingual Immunotherapy is a form of immunotherapy that involves placing the allergen extract under the tongue. An allergist gives patient small doses of an allergen under the tongue to boost the tolerance to the substance and reduce its symptoms. At present, the only forms of SLIT approved by the FDA are tablets for ragweed, northern pasture grasses like timothy, and dust mites. The safety and efficacy of allergy drops is yet being established by the FDA, and they are only used without label in the United States. The possible advantages of sublingual treatment are those of no use of injections, comparatively few regular doctor visits, possibility of home dosing after the first treatment, also a lower risk of serious reactions. Parents of young children often prefer sublingual immunotherapy as their child does not have to have regular injections. The main disadvantage of this form of treatment is its cost as more allergen needs to be swallowed than injected, this results in the cost per allergen being more expensive than that of injected treatments.


Keywords: Sublingual immunotherapy, allergies, SLIT, SCIT, AIT, allergen.

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Author Biographies

Sonia T Sevlani, Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

Sheetal Gondkar, Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

Ravindranath Saudagar, Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik-422213, Maharashtra, India

Department of Pharmaceutical Chemistry, R. G. Sapkal College of Pharmacy,   Anjaneri, Nashik-422213, Maharashtra, India

References

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6. Harish, Ziv. PCT/US Patent, WO 2014/205008 A1.
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How to Cite
Sevlani, S. T., Gondkar, S., & Saudagar, R. (2019). A REVIEW Sublingual Immunotherapy: An Innovative Alternative for Allergies. Journal of Drug Delivery and Therapeutics, 9(3), 716-718. https://doi.org/10.22270/jddt.v9i3.2899

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