Phytochemicals and GC–MS analysis of bioactive compounds present in ethanolic leaves extract of Taraxacum officinale (L).

  • P Sasikala P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.
  • S Ganesan P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.
  • T Jayaseelan P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.
  • S Azhagumadhavan P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.
  • M Padma P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.
  • S Senthilkumar P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.
  • P Mani Dept. of Biotechnology, Annai College of Arts and Science, Kumbakonam, Tamilnadu, India.

Abstract

Objective: To identify the phytochemical constituents present in ethanolic leaves extract of Taraxacum officinale (T. o) and to elucidate the bioactive compounds.


Methods: The fresh leaves of T. officinale (1000g) were shade dried at room temperature for 30 days and the dried leaves were made into a fine powder. The ethanolic leaves extract obtained was dried with help of desiccator and rotatory evaporator. The dried samples tested for phytochemical analysis and bioactive compounds profiling through GC-MS analysis.


Results: The phytochemical screening studies showed presence of alkaloids, flavonoids, phenol, cardiac glycosides and anthraquinones. in the leaves extract of T. officinale. GC-MS analysis showed 10 essential bioactive compounds and it revealed the presence of significant anticancer, Antimicrobial  and antidiabetic compounds.


Conclusions: The ethanol extract of T. o possess the most important phytochemical compounds and it has various  medicinal  properties to cure dangerous diseases and disorders.


Keywords: Taraxacum officinale, Phytochemicals analysis, GC–MS analysis, Biological compounds.

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Author Biographies

P Sasikala, P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

S Ganesan, P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

T Jayaseelan, P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

S Azhagumadhavan, P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

M Padma, P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

S Senthilkumar, P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

P.G. and Research Department of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College (Autonomous), Poondi - 613 503, Thanjavur District, Tamil Nadu, India.

P Mani, Dept. of Biotechnology, Annai College of Arts and Science, Kumbakonam, Tamilnadu, India.

Dept. of Biotechnology, Annai College of Arts and Science, Kumbakonam, Tamilnadu, India.

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How to Cite
Sasikala, P., Ganesan, S., Jayaseelan, T., Azhagumadhavan, S., Padma, M., Senthilkumar, S., & Mani, P. (2019). Phytochemicals and GC–MS analysis of bioactive compounds present in ethanolic leaves extract of Taraxacum officinale (L). Journal of Drug Delivery and Therapeutics, 9(1), 90-94. https://doi.org/10.22270/jddt.v9i1.2175