Mini-review: Combination and Co-delivery in Cancer Treatment Efficacy
The mini-review focuses on the cancer therapy treatment efficacy as enhanced through combination and co-delivery methods. The focus is on nano-delivery methods and how in spite of the challenges in developing co-delivery, their potential is analyzed across different clinical fields.
Keywords: Cancer therapy, combination, co-delivery, nano-delivery, nano micelles, nanoscale, nanoparticles
2. Han R., Sun Y., Kang C., Sun H. & Wei W. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and doxorubicin for enhanced therapeutic efficacy. Journal of Drug Targeting 2017; 25:140-148.
3. Duan Y., et al. Bioactivity evaluation-based ultra high-performance liquid chromatography coupled with electrospray ionization tandem quadrupole-time-of-flight mass spectrometry and novel distinction of multi-subchemome compatibility recognition strategy with Astragali Radix-Fructus Corni herb-pair as a case study. J Pharm Biomed Anal 2016; 129:514-534.
4. Sun Y., et al. Co-delivery of dual-drugs with nanoparticle to overcome multidrug resistance. European Journal of BioMedical Research 2016; 2:12-18.
5. Ai R., et al. Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes. Nat Commun 2018; 9:1921.
6. Fan S., et al. Computationally expanding infinium HumanMethylation450 BeadChip array data to reveal distinct DNA methylation patterns of rheumatoid arthritis. Bioinformatics 2016; 32:1773-1778.
7. Liu F., Sun Y. & Kang C. Controlling Amphiphilic Functional Block Copolymers’ Self-Assembly: From Structure to Size. (2016).
8. Song L., et al. Crocetin inhibits lipopolysaccharide-induced inflammatory response in human umbilical vein endothelial cells. Cellular Physiology and Biochemistry 2016; 40:443-452.
9. Sun Y., Kang C., Liu F. & Song L. Delivery of antipsychotics with nanoparticles. Drug Development Research 77, 393-399 (2016).
10. Kang C., et al. Delivery of nanoparticles for treatment of brain tumor. Current Drug Metabolism 2016; 17:745-754.
11. Xue X., et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel–Lindau interaction through shape-based screening and cascade docking. PeerJ 2016; 4:e2757.
12. Hersch S.J., et al. Divergent protein motifs direct elongation factor P-mediated translational regulation in Salmonella enterica and Escherichia coli. MBio 2013; 4:e00180-00113.
13. Shuhong X., et al. Dynamic expression of AQP4 in early stageof ischemia/reperfusion rats and cerebral edema. Chinese Pharmacological Bulletin 2016; 32:1433-1441.
14. Peng J., et al. Enhanced Liver Regeneration After Partial Hepatectomy in Sterol Regulatory Element-Binding Protein (SREBP)-1c-Null Mice is Associated with Increased Hepatocellular Cholesterol Availability. Cellular Physiology and Biochemistry 2018; 47:784-799.
15. Yang, Z., et al. Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation. Journal of Controlled Release 2016; 243:160-171.
16. Kang C., Hernandez V.A. & Hu K. Functional interaction of the two-pore domain potassium channel TASK-1 and caveolin-3. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 2017; 1864:1537-1544.
17. Waller A.P., et al. GLUT12 functions as a basal and insulin-independent glucose transporter in the heart. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 2013; 1832:121-127.
18. Li Q., et al. Identification by shape-based virtual screening and evaluation of new tyrosinase inhibitors. PeerJ 2018; 6:e4206.
19. Chen, Y., et al. Identification of 4-aminoquinoline core for the design of new cholinesterase inhibitors. PeerJ 2016; 4:e2140.
20. Kang C. & Hu K. Impact of hypoxia in the expression and regulation of the TASK-1 potassium channel in cardiac myocytes. The FASEB Journal 2016; 30:lb598-lb598.
21. Kang C. Ion channels, protein kinase C and caveolae in cardioprotection, (The Ohio State University, 2015).
22. Yung B.C., et al. Lipid nanoparticles composed of quaternary amine–tertiary amine cationic lipid combination (QTsome) for therapeutic delivery of AntimiR-21 for lung cancer. Molecular pharmaceutics 2016; 13:653-662.
23. Cheng X., et al. Lipid Nanoparticles Loaded with an Antisense Oligonucleotide Gapmer Against Bcl-2 for Treatment of Lung Cancer. Pharmaceutical research 2017; 34:310-320.
24. Fan S. & Chi W. Methods for genome-wide DNA methylation analysis in human cancer. Brief Funct Genomics 2016; 15:432-442.
25. Kang C. & Hu K. Modulation of the two-pore domain potassium channel TASK-1 by caveolin-3. The FASEB Journal 2015; 29:845.814.
26. Qiao H., et al. Orally delivered polycurcumin responsive to bacterial reduction for targeted therapy of inflammatory bowel disease. Drug Delivery 2017; 24:233-242.
27. Qiao H., et al. Redox-triggered mitoxantrone prodrug micelles for overcoming multidrug-resistant breast cancer. Journal of drug targeting 2018; 26:75-85.
28. Kang C., Sun Y., Wang,M. & Cheng X. Nanosized camptothecin conjugates for single and combined drug delivery. European Journal of BioMedical Research 2016; 2:8-14.
29. Liu F., Sun Y., Kang C. & Zhu H. Pegylated Drug Delivery Systems: From Design to Biomedical Applications. Nano LIFE 2016; 6:1642002.
30. Sun Y., Kang C., Yao Z., Liu F. & Zhou Y. Peptide-Based Ligand for Active Delivery of Liposomal Doxorubicin. Nano Life 2016; 6:1642004.
31. Fan S., Huang K., Ai R., Wang M. & Wang W. Predicting CpG methylation levels by integrating Infinium HumanMethylation450 BeadChip array data. Genomics 2016; 107:132-137.
32. Kang C., Qin J., Osei W. & Hu K. Regulation of protein kinase C-epsilon and its age-dependence. Biochemical and Biophysical Research Communications 2017; 482:1201-1206.
33. Sun Y., et al. RGD Peptide‐Based Target Drug Delivery of Doxorubicin Nanomedicine. Drug development research 2017; 78:283-291.
34. Kang C. & Hu K. Role of caveolin-3 in adenosine-induced increase in mitochondrial PKCε. The FASEB Journal 2013; 27:1191.1197-1191.1197.
35. Cheng X. & Lee R.J. The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery. Adv Drug Deliv Rev 2016; 99:129-137.
36. Sun Y. & Kang C. Self-Assembly of Peptides into Hydrogel. Journal of Organic & Inorganic Chemistry 2016; 2:5.
37. Yao Z., Sun Y. & Kang C. Structure and self-assembly of multicolored Naphthalene Diimides Semiconductor. Nano LIFE 2016; 6:1642007.
38. Cheng X., et al. T7 Peptide-Conjugated Lipid Nanoparticles for Dual Modulation of Bcl-2 and Akt-1 in Lung and Cervical Carcinomas. Molecular pharmaceutics 2018; 15:4722-4732.
39. Zhong X., Sun Y., Kang C. & Wan G. The theory of dielectrophoresis and its applications on medical and materials research. European Journal of BioMedical Research 2017; 2:7-11.
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