EVALUATION OF DRUG PRESCRIPTION PATTERN USING WORLD HEALTH ORGANIZATION PRESCRIBING INDICATORS IN TIKUR ANBESSA SPECIALIZED HOSPITAL: A CROSS–SECTIONAL STUDY

  • Alemseged Beyene Berha Clinical Pharmacy Unit, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
  • Nathan Seyoum Department of Pharmaceutics & Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia

Abstract

Background: Irrational use of antibiotics is a worldwide problem that contributes to dramatically increasing resistance and causes significant mortality, morbidity, and increased health care costs. In order to ensure the quality of health and medical care for patients and the community as a whole the proper use of medicines is an important element. Evaluation of drug use patterns with the WHO core drug use indicators is showing progressively more essential to promote rational drug use in developing countries. The main aim of this study was to assess the drug prescription pattern using WHO prescribing indicators at the Medical Outpatient Pharmacy in Tikur Ambessa Specialized Hospital (TASH).

Methods: A retrospective cross-sectional survey was designed to the claim data .A sample of 2000 prescriptions was selected using systematic random sampling to determine the prescribing pattern from a total of 6,462 prescriptions written by medical interns, residents and senior physicians for a one -year period from February 2015 to January 2016. The raw data was cleaned, entered and analyzed using SPSS version 21.0 of the computer software. The results were summarized using texts and tables.

Results: The average number of drugs per encounter was 2.84 +1.58 in the range of 1 to 9. The total number of the drugs which were prescribed by generic name was 97.9%.  Of these, the total number of prescribed drugs which were included in the Ethiopian National Essential Medicine List was 99.3%. The present study highlighted the under use of antibiotics which accounts 6.6% (378), with majority being Crystalline Penicillin  27.1 % (94), followed by  Amoxicillin 17.8%(62) and  Ciprofloxacin 14.1% (49). A total of 8.4% (480) drugs were prescribed as injections.

Conclusion: On the basis of the finding of this study, the drug prescription pattern did not meet the WHO core drug use indicators criteria.  It seems that there is a need for improvement of the prescribing patterns in the hospitals.  Therefore, the federal ministry of health and drug regulatory body's commitment will be required to bring about changes in drug use policies, organize health systems and legislative structures as required in order to foster rational drug use in the country.

Keywords: Prescribing Indicators, Prescription, Rational Prescribing.

 

 

Downloads

Download data is not yet available.

Author Biographies

Alemseged Beyene Berha, Clinical Pharmacy Unit, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Clinical Pharmacy Unit, Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Nathan Seyoum, Department of Pharmaceutics & Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia
Department of Pharmaceutics & Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia

References

1. Mahalli AAE. WHO/INRUD drug prescribing indicators at primary health care centres in Eastern province, Saudi Arabia. Eastern Mediterranean Health Journal. 2012; 18(11):6.
2. Karande S, Sankhe P, Kulkarni M. Patterns of prescription and drug dispensing. Indian journal of pediatrics. 2005; 72(2):117-21.
3. Hogerzeil H. Promoting the rational use of medicines. WHO Essential Drugs and Medicines Policy. 2002.
4. T. P. G. M. de Vries RHH, H. V. Hogerzeil, D. A. Fresle. Guide to Good Prescribing. Geneva, Switzerland.: WHO, 1994.
5. Hogerzeil HV. Promoting rational prescribing: an international perspective. British Journal of Clinical Pharmacy. 1995; 39:1-6.
6. Ntšekhe M, Hoohlo-Khotle N, Tlali M, Tjipura D. Antibiotic Prescribing Patterns at Six Hospitals in Lesotho. Strengthening Pharmaceutical Systems, Center for Pharmaceutical Management, Management Sciences for Health. 2011; 1:40.
7. ASTBURY M. Professional Standards for Hospital Pharmacy: Optimising Patient Outcomes from Medicines. Royal Pharmaceutical Society. 2014; 2.
8. Mrs M. Anker MPB-J, Dr. Bimo, Prof A. Chowdhury. How to Investigate Drug Use In Facilities: Selected Drug Use Indicators. WHO/DAP/931. 1993.
9. Hospital TA. Tikur Ambessa Hospital. aaueduet/aaubeta/chs/tikur-anbessa-specialized hospital/background-of-tikur-anbessa-hospital/. 2015.
10. Organization WH. How to investigate drug use in health facilities: selected drug use indicators. 1993.
11. Isah AO R-DD, Quick J, Laing R, Mabadeje AFB. The development of standard values for the WHO drug use prescribing indicators.archiveswhoint/produc2004/rducd/ ICIUM_Posters/1a2_ txthtm. 2016.
12. Lalan BK, Hiray R, Ghongane B. Drug prescription pattern of outpatients in a tertiary care teaching hospital in Maharashtra. Int J Pharm Bio Sci. 2012; 3(3):225-9.
13. Desalegn AA. Assessment of drug use pattern using WHO prescribing indicators at Hawassa University teaching and referral hospital, south Ethiopia: a cross-sectional study. Hawassa: Hawassa University; 2013.
14. Zeruesenay Desta TA, Asfawoseen Gebre-Yohannes, Alemayehu Worku. Drug prescribing patterns for outpatients in three hospitals in north-west Ethiopia. Ethiopian Journal for Health Development. 2002; 16(2):9.
15. Organization WH. How to investigate drug use in health facilities Selected drug use indicators. 1993.
16. Guyon A.B. BA, Ahmed J.U. , Ahmed A.U. , Alam M.S. , . A baseline survey on use of drugs at the primary health care level in Bangladesh. Bull World Health Organ. 1994; 72(2):265-71.
17. Nifkar S KA, Majdzadeh R, Abdollahi M, . Monitoring of National Drug Policy (NDP) and its standard indicators; conformity to decisions of the nation drug selecting committee in Iran. BMC Int Healt Human Rights. 2005; 5(5):5.
18. Bhartiy SS SM, Nandeshwar S, Tiwari SC. Pattern of prescribing practices in the Madhya Pradesh, India. Kathmandu University Medical Journal 2008; 6(21):55-9.
19. Sharma P, Kapoor B. Study of Prescribing Pattern for Rational Drug Theraphy. 2003.
20. Birhanu Demeke FM, Admassu Assen, Wondim Melkam, Solomon Abrha, Birhanetensay Masresha, Tigist Asefa. Evaluation of drugs utilization pattern using WHO prescribing indicators in Ayder Referral Hospital, Northern Ethiopia. International Journal of Pharma Sciences and Research (IJPSR). 2015; 6(2):342-7.
21. Tigistu Alemu Desse TCE. Assessment of drug use pattern using World Health Organization core drug use indicators at Debre Markos Referral Hospital, Northwest Ethiopia. International Journal of Innovative Pharmaceutical Sciences and Research. 2014; 2(7):1270-88.
22. Zaran F, Rybak M. Pharmacy-based antimicrobial-monitoring service. American Journal of Health-System Pharmacy. 1992; 49(7):1701-6.
23. Kunin CM. Evaluation of antibiotic usage: a comprehensive look at alternative approaches. Review of infectious diseases. 1981; 3(4):745-53.
24. Lenjisa JL, Fereja TH. A Retrospective Analysis of Prescribing Practices through WHO Prescribing Indicators at Four Selected Hospitals of West Ethiopia. Journal of Bioanalysis & Biomedicine. 2014; 6(2):29.
25. Bayew T, Wubshet H, Zeryawkal E. Do Private Health Institutions Prescribe Drugs more Irratioinally than the Publics? A Year Long Comparative Evaluation of Prescribing Indecators, Wolkite Town, South West Ethiopia. Indian Journal of Pharmacy Practice. 2013; 6(2).
26. Organization WH. Assessment of the pharmaceutical sector in Ethiopia. 2003.
27. Karimi A, Haerizadeh M, Soleymani F, Haerizadeh M, Taheri F. Evaluation of medicine prescription pattern using World Health Organization prescribing indicators in Iran: A cross-sectional study. Journal of research in pharmacy practice. 2014; 3(2):39.
28. Mulugeta T Angamo NTWaNJR. Assessment of Patterns of Drug use by using World Health Organization’s Prescribing, Patient Care and Health facility indicators in Selected Health Facilities in Southwest Ethiopia. Journal of Applied Pharmaceutical Science. 2011; 1(7):62-6.
29. Satish Kumar B.P. PG, Praveen Kumar, B. Anjaiah. A study on drug use pattern using WHO prescribing indicators in inpatients of Medicine Department in a rural teritiary care teaching hospital. Indo American Journal of Pharmaceutical Research. 2015; 5(5):2231.
30. Nirajan Bhattarai DB, Sajina Kusi, Kripa Adhikari and Sagar Basnet. Prescription pattern in various medical wards of Tribhuvan University Teaching Hospital under World Health Organization (WHO) prescription indicators. International Journal of Pharma Sciences 2014; 4(3):572-6.
31. Amha Gebremedhin DS, Tesgaye Aster, Aziza Shad and Marcia Landskroener,. Tikur Anbessa (Black Lion) Hospital Belgium: International Network for Cancer Treatment and Research; 2016 [cited 2016 July 23 2016].
32. Fereja JLLaTH. A Retrospective Analysis of Prescribing Practices through WHO Prescribing Indicators at Four Selected Hospitals of West Ethiopia. Journal of Bioanalysis and Biomedicine. 2014; 6(4):29-32.
Statistics
1001 Views | 457 Downloads
How to Cite
1.
Berha A, Seyoum N. EVALUATION OF DRUG PRESCRIPTION PATTERN USING WORLD HEALTH ORGANIZATION PRESCRIBING INDICATORS IN TIKUR ANBESSA SPECIALIZED HOSPITAL: A CROSS–SECTIONAL STUDY. JDDT [Internet]. 14Jan.2018 [cited 8Dec.2021];8(1):74-0. Available from: http://jddtonline.info/index.php/jddt/article/view/1652