PRELIMINARY PHYTOCHEMICAL AND DIURETIC SCREENING OF ETHANOLIC AND AQUEOUS EXTRACT OF ZINGIBER OFFICINALE

  • Manvendra Badore GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
  • Pallavi Mahajan GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
  • Prabhat Das GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
  • Narendra Badore GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
  • Sujit Pillai GRY Institute of Pharmacy, Borawan, Khargone, M.P., India

Abstract

The present study was to evaluate Diuretic activity of ethanolic and aqueous extracts of Zingiber officinale Rhizome in wistar rats. Ethanolic and aqueous extracts were administered to experimental rats orally at the doses of 500 mg/kg p.o.  Furosemide (5 mg/kg) was used as positive control in the study. The diuretic effect of the extract was evaluated by measuring urine volume & sodium content. Urine volume was significantly increased by ethanolic extract in comparison to the aqueous and control group, while the excretion of sodium was also increased by extract. The ethanolic extract had the additional advantage over aqueous extract. We can conclude that ethanolic extract of Zingiber officinale produced notable diuretic effect which appeared to be comparable to that produced by the reference diuretic furosemide.

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Author Biographies

Manvendra Badore, GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
Pallavi Mahajan, GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
Prabhat Das, GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
Narendra Badore, GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
GRY Institute of Pharmacy, Borawan, Khargone, M.P., India
Sujit Pillai, GRY Institute of Pharmacy, Borawan, Khargone, M.P., India

GRY Institute of Pharmacy, Borawan, Khargone, M.P., India

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How to Cite
Badore, M., Mahajan, P., Das, P., Badore, N., & Pillai, S. (2017). PRELIMINARY PHYTOCHEMICAL AND DIURETIC SCREENING OF ETHANOLIC AND AQUEOUS EXTRACT OF ZINGIBER OFFICINALE. Journal of Drug Delivery and Therapeutics, 7(7), 170-172. https://doi.org/10.22270/jddt.v7i7.1624