Histopathological Changes in Ovarian Tissues of Rats Underwent Ovarian Ischemia-Reperfusion Injury

Authors

Abstract

This study investigates histopathological changes in ovarian tissues of rats subjected to ischemia-reperfusion (I/R) injury, a condition where restored blood flow causes cellular stress and potential damage. Rats were divided into three groups: control, ischemia, and ischemia-reperfusion. Histological analysis revealed that ischemic ovaries exhibited increased follicular degeneration, atretic follicles, and inflammatory infiltration. The ischemia-reperfusion group showed even more pronounced damage, including disrupted cellular structures and severe vascular congestion. These findings highlight the exacerbated tissue damage caused by reperfusion, underscoring the complex impact of I/R injury on ovarian tissue integrity.

Keywords: ovary, ischemia, reperfusion, histology

Keywords:

ovary, ischemia, reperfusion

DOI

https://doi.org/10.22270/jddt.v14i11.6887

Author Biographies

Esranur Atiç , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Muhyiddin Sancar , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Mehmet Uğur Karabat , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Şehmus Kaplan , https://orcid.org/0000-0003-4446-8142

https://orcid.org/0000-0003-4446-8142

Fırat Aşır, Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Murat Akkuş , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

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Published

15-11-2024
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How to Cite

1.
Atiç E, Sancar M, Karabat MU, Kaplan Şehmus, Aşır F, Akkuş M. Histopathological Changes in Ovarian Tissues of Rats Underwent Ovarian Ischemia-Reperfusion Injury. J. Drug Delivery Ther. [Internet]. 2024 Nov. 15 [cited 2024 Dec. 6];14(11):58-62. Available from: https://jddtonline.info/index.php/jddt/article/view/6887

How to Cite

1.
Atiç E, Sancar M, Karabat MU, Kaplan Şehmus, Aşır F, Akkuş M. Histopathological Changes in Ovarian Tissues of Rats Underwent Ovarian Ischemia-Reperfusion Injury. J. Drug Delivery Ther. [Internet]. 2024 Nov. 15 [cited 2024 Dec. 6];14(11):58-62. Available from: https://jddtonline.info/index.php/jddt/article/view/6887