Histopathological Alterations in Placentas of Severe and Non-Severe Preeclamptic Patients

Authors

Abstract

Preeclampsia is a significant pregnancy complication associated with vascular lesions and trophoblastic invasion, leading to substantial maternal and fetal risks. This study compares histopathological changes in placental structures among severe and non-severe preeclamptic patients. Placental tissues were analyzed, revealing that preeclampsia groups showed notable villous degeneration, increased fibrin deposition, vascular dilatation, congestion, and syncytial node formation. Severe preeclampsia further exhibited intensified hemorrhage and leukocyte infiltration. These findings underscore the link between preeclampsia severity and placental dysfunction, providing insights into the pathological mechanisms affecting perinatal outcomes.

Keywords: placenta, preeclampsia, HELLP, histology

Keywords:

placenta, preeclampsia, HELLP, histology

DOI

https://doi.org/10.22270/jddt.v14i11.6886

Author Biographies

Şehmus Kaplan , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye 

Mehmet Uğur Karabat , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye 

Esranur Atiç , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye 

Muhyiddin Sancar , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye 

İlkan Alkan, Department of Fertilization and Artificial Insemination, Veterinary Faculty, Dicle University, Diyarbakır, Turkey

Department of Fertilization and Artificial Insemination, Veterinary Faculty, Dicle University, Diyarbakır, Turkey

 

Fırat Aşır , Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye

Department of Histology and Embryology, Medical Faculty, Dicle University, Diyarbakır, Türkiye 

References

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Published

15-11-2024
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How to Cite

1.
Kaplan Şehmus, Karabat MU, Atiç E, Sancar M, Alkan İlhan, Aşır F. Histopathological Alterations in Placentas of Severe and Non-Severe Preeclamptic Patients. J. Drug Delivery Ther. [Internet]. 2024 Nov. 15 [cited 2024 Dec. 6];14(11):54-7. Available from: https://jddtonline.info/index.php/jddt/article/view/6886

How to Cite

1.
Kaplan Şehmus, Karabat MU, Atiç E, Sancar M, Alkan İlhan, Aşır F. Histopathological Alterations in Placentas of Severe and Non-Severe Preeclamptic Patients. J. Drug Delivery Ther. [Internet]. 2024 Nov. 15 [cited 2024 Dec. 6];14(11):54-7. Available from: https://jddtonline.info/index.php/jddt/article/view/6886