Herbal Drug Use to Treat Urolithiasis: An Updated Review

Authors

  • Roushan Bhaskar Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India
  • Ritu Rani Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India https://orcid.org/0009-0009-0013-6016
  • Ajeet Pal Singh Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India https://orcid.org/0000-0002-1212-5770
  • Amar Pal Singh Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India https://orcid.org/0000-0003-0027-2869

Abstract

World Health Organization (WHO) estimates that 12% of the world's population suffers from urolithiasis, a disorder that causes stones to develop in the kidney, bladder, and/or urethra (the urinary system). The illness increases the likelihood of developing chronic renal illnesses in addition to impairing kidney function. Three phases make up the mechanism for the production of stones: nucleation, growth, and aggregation of crystals. Because of their medicinal and antioxidant properties, as well as their active substances, medicinal plants have positive benefits on human health. The traditional medicinal herbs' diuretic qualities are increasingly being backed by scientific research. Urinary calculi patients complain of hematuria, discomfort, or infection. Individuals with tiny, non-obstructing stones or staghorn calculi have moderate, easily managed symptoms in addition to other symptoms. The illness increases the likelihood of developing chronic renal illnesses in addition to impairing kidney function. Therefore, a plant's or a herbal formulation's antiurolithiatic effect may be the result of a combination of its antioxidant, diuretic, and crystallization-inhibiting properties.

Keywords: Urolithiasis, diuresis, herbal drug, calcium oxalate stone

Keywords:

Urolithiasis, diuresis, herbal drug, calcium oxalate stone, Urolithiasis, diuresis, herbal drug, calcium oxalate stone

DOI

https://doi.org/10.22270/jddt.v14i11.6866

Author Biographies

Roushan Bhaskar , Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

Ritu Rani , Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

Ajeet Pal Singh , Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

Amar Pal Singh , Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India

References

1. Eromedogane M, Okantu J, Ebawun E, "Herbal Interventions for Urolithiasis: A Systematic Evaluation of Efficacy and Safety" Inv Bio [Internet], 2024;3(3):78-82.

2. Atre O, Bhawar S, Dhamak k, "A brief review on kidney stone, herbal plants used for kidney stone along with their pharmacological action and their marketed products" World journal of pharmaceutical Research, 12(6) :71-90.

3. Shraddha G, Shraddha S, "A review on antiurolithiatic activity of some herbal drugs" world journal of pharmaceutical research, 10(2) :406-411.

4. Shahsavari, Somayeh "An Overview of the Most Important Medicinal Plants Used in Iranian Traditional Medicine for the Treatment of Kidney Stones:A mini-review article" Plant Biotechnology Persa, 2021: 3. https://doi.org/10.52547/pbp.3.1.4

5. El-Tantawy WH, Temraz A, Mohamed SA "Herbal Extracts Acting as Diuretics: A Comprehensive Review" Egypt. J. Chem., 2024;67(3):387- 399 https://doi.org/10.21608/ejchem.2024.254378.8972

6. Malabadi, Ravindra M, Neelambika C, Raju "Updates on herbal remedy for kidney stone chronic disease" 2021.

7. Alonso-Castro A, Alba-Betancourt C, Yáñez Barrientos E, Luna-Rocha C, Páramo-Castillo A, Aragón-Martínez O, Zapata-Morales J, Cruz Jiménez G, Gasca-Martínez D, González-Ibarra A, Álvarez-Camacho D, Devezé-Álvarez M "Diuretic activity and neuropharmacological effects of an ethanol extract from Senna septemtrionalis (Viv.) HS Irwin & Barneby (Fabaceae)" Journal of Ethnopharmacology ,2019; 239 :1-9. https://doi.org/10.1016/j.jep.2019.111923 PMid:31034951

8. Ramon P, Bergmann D, Abdulla H, Sparks J, Omoruyi F "Bioactive ingredients in K. pinnata extract and synergistic effects of combined K. pinnata and metformin preparations on antioxidant activities in diabetic and non-diabetic skeletal muscle cells" International Journal of Molecular Science, 2023;24(7):6211. https://doi.org/10.3390/ijms24076211 PMid:37047182 PMCid:PMC10094480

9. Ridwan, Hanna & Megantara, Sandra & Levita, Jutti "Review of the phytotherapy for nephrolithiasis" Jurnal Ilmiah Farmako Bahari, 2024; 15. 92. https://doi.org/10.52434/jifb.v15i1.2877

10. Asif M, Jabeen Q, Majid A, Atif M "Diuretic activity of aqueous extract of Nigella sativa in albino rats. Acta Pharmaceutical, 2015;72(1):129-135.

11. Nardos A, Makonnen E, Debella A "Effects of crude extracts and fractions of Moringa stenopetala (Baker f) Cufodontis leaves in normoglycemic and alloxan-induced diabetic mice" African Journal of Pharmacy and Pharmacology, 2011;5(20):2220-2225. https://doi.org/10.5897/AJPP11.318

12. Patel V, Rathod I, Patel J, Brahmbhatt M, "Anti urolithiatic and natriuretic activity of steroidal constituents of Solanum xanthocarpum" Der Pharma Chemica. 2010; 2(1):173-176.

13. Sangkhathat, Surasak "An Appraisal of Totally Implantable Venous Access Devices in Pediatric Cancers" Siriraj Medical Journal, 2020;72:95-102. https://doi.org/10.33192/Smj.2020.13

Published

15-11-2024
Statistics
Abstract Display: 26
PDF Downloads: 26
PDF Downloads: 2

How to Cite

1.
Bhaskar R, Rani R, Singh AP, Singh AP. Herbal Drug Use to Treat Urolithiasis: An Updated Review. J. Drug Delivery Ther. [Internet]. 2024 Nov. 15 [cited 2024 Dec. 6];14(11):146-9. Available from: https://jddtonline.info/index.php/jddt/article/view/6866

How to Cite

1.
Bhaskar R, Rani R, Singh AP, Singh AP. Herbal Drug Use to Treat Urolithiasis: An Updated Review. J. Drug Delivery Ther. [Internet]. 2024 Nov. 15 [cited 2024 Dec. 6];14(11):146-9. Available from: https://jddtonline.info/index.php/jddt/article/view/6866