A Comprehensive Review on Niosomes in Drug Delivery and Recent Advancements

Abstract

The recent emphasis on nanocarrier development for drug delivery stems from the need to target specific diseased areas while sparing healthy tissues. Effective and safe drug administration has long posed challenges in medicine. Over the past decade, the emergence of vesicles as a means to enhance drug delivery has captivated researchers in the field of drug delivery systems. Among vesicular systems, niosomes have gained attention due to their nonionic features. Unlike liposomes, niosomes offer superior stability, making them a preferred choice. Non-ionic in nature niosomes offer unique advantages in drug delivery providing a versatile platform for encapsulating various drugs to enhance bioavailability and ensure controlled release. Understanding preparation techniques enables tailored applications from oral to transdermal delivery. Characterization methods such as morphology and particles size are pivotal in ensuring the stability and effectiveness of niosomes. Applications span cancer therapy, diagnostic imaging, and vaccination adjuvants, showcasing niosomes versatility. Ongoing research reflects dynamic efforts to enhance capabilities, emphasizing their pivotal role in evolving drug delivery systems. In this comprehensive review, we aim to encapsulate fundamental aspects of niosomes, encompassing diverse preparation methods, various niosomal types, methods for characterization and the advancements witnessed in niosomal research over the past decade, drawing insights from a literature review.


Keywords: Niosomes, Drug delivery, Nanocarrier, Vesicles, Nanomedicines

Keywords: Niosomes, Drug delivery, Nanocarrier, Vesicles, Nanomedicines

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Author Biographies

Charlisar Teron, Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

Abhranil Bhuyan, Master of Pharmacy, Faculty of Pharmaceutical Sciences, Assam down town University

Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

Prasurjya Saikia, Master of Pharmacy, Faculty of Pharmaceutical Sciences, Assam down town University

Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

Sunmon Raj Dutta, Master of Pharmacy, Faculty of Pharmaceutical Sciences, Assam down town University

Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

Himanshu Gogoi, Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

Shivam Rongpi, Master of Pharmacy, Faculty of Pharmaceutical Sciences, Assam down town University

Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, India, PIN – 781026

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Teron C, Bhuyan A, Saikia P, Dutta SR, Gogoi H, Rongpi S. A Comprehensive Review on Niosomes in Drug Delivery and Recent Advancements. JDDT [Internet]. 15Jun.2024 [cited 17Jul.2024];14(6):262-73. Available from: https://jddtonline.info/index.php/jddt/article/view/6651