Stabilization of the pharmaceutical finished dosages form by using various techniques

  • Vikas Chandel DGM Formulation Development, Anthea Pharma Pvt. Ltd., Hyderabad, Telangana, India
  • Hemendra Pratap Singh B N Institute of Pharmaceutical Sciences, B N University, Udaipur, Rajasthan
  • Nilesh Rarokar G H Raisoni Institute of Life Sciences, Department of Pharmaceutics, Shradha Park, Hingna MIDC, Nagpur-440016, India
  • Kamlesh Wadher BCYRC’S KDK College of Pharmacy and Research Institute , Nandanvan, Nagpur-440009, India

Abstract

The stabilization of pharmaceuticals means that the drug product is physically, chemically and microbiologically stable at the recommended storage condition throughout the predefined shelf life of the product. Pharmaceutical formulations irrespective of its physical states have been used for their efficacy and safety so for as its therapeutic activity is concern. Stability of dosage forms is the ability of drugs to remains unaffected by environmental condition viz. temperature, humidity and microbiological contamination. This research work is an attempt to stabilize the drug product at controlled room temperature for the drug product which is stable at refrigerated storage condition. Hence the aim of present study was development and stabilization of the drug product at room temperature. Investigation of alternate manufacturing processes for stabilization of the drug product at controlled room temperature was one of the objectives of the work.


Keywords: Stability, shelf life, lyophilization, freeze drying

Keywords: Stability, shelf life, lyophilization, freeze drying

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Author Biographies

Vikas Chandel, DGM Formulation Development, Anthea Pharma Pvt. Ltd., Hyderabad, Telangana, India

DGM Formulation Development, Anthea Pharma Pvt. Ltd., Hyderabad, Telangana, India

Hemendra Pratap Singh, B N Institute of Pharmaceutical Sciences, B N University, Udaipur, Rajasthan

B N Institute of Pharmaceutical Sciences, B N University, Udaipur, Rajasthan, India

Nilesh Rarokar, G H Raisoni Institute of Life Sciences, Department of Pharmaceutics, Shradha Park, Hingna MIDC, Nagpur-440016, India

G H Raisoni Institute of Life Sciences, Department of Pharmaceutics, Shradha Park, Hingna MIDC, Nagpur-440016, India

Kamlesh Wadher, BCYRC’S KDK College of Pharmacy and Research Institute , Nandanvan, Nagpur-440009, India

BCYRC’S KDK College of Pharmacy and Research Institute , Nandanvan, Nagpur-440009, India

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1.
Chandel V, Singh HP, Rarokar N, Wadher K. Stabilization of the pharmaceutical finished dosages form by using various techniques. JDDT [Internet]. 15Jun.2024 [cited 17Jul.2024];14(6):44-0. Available from: https://jddtonline.info/index.php/jddt/article/view/6619