Phytochemicals properties and antimicrobial activities of Carica papaya and Balanites aegyptiaca’ seeds aqueous infusion and decoction extracts

Authors

  • Assétou OUEDRAOGO Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso https://orcid.org/0009-0007-4720-4501
  • Philippe Augustin NIKIEMA Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso https://orcid.org/0000-0002-7414-3042
  • Marguerite Edith Malatala NIKIEMA Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso https://orcid.org/0000-0003-2926-5718
  • Josias Gérard YAMEOGO Laboratoire du Développement du Médicament (LADME), Centre de Formation de Recherche et d’Expertises en Sciences du Médicament (CEA-CFOREM), Université Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso
  • Bernadette Pane SOURABIE Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)
  • Belinda Ramata Hafouo BASSAVE Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT) https://orcid.org/0000-0002-1278-5509
  • Oueogo NIKIEMA Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT) https://orcid.org/0000-0003-1968-226X
  • Florent Wendinmi Bertrand GOUMBRI Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT) https://orcid.org/0000-0002-6375-3398
  • Nicolas BARRO Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso https://orcid.org/0000-0003-2933-4357

Abstract

Carica papaya and Balanites aegyptiaca seeds extract have several uses, from food to traditional medicine. This study aims to determine their phytochemicals compound and appreciate their antimicrobial properties against clinical strains. Polyphenolic content was determined with standard methods while DPPH radical scavenging activity is used to appreciate the antioxidant properties, using ascorbic acid as standard. Antimicrobial activities were performed according to the inhibition diameters, using agar diffusion method. Minimum inhibitory concentrations and Minimum fungicidal concentrations were established based on broth dilution methods. The extraction yield is ranged between 6.3 and 20.3%. The results shown polyphenolic content varying from 1256.13±21.09 to 2315.81±53.52 µg GAE/100 mL for Carica papaya and from 303.98±0.93 to 948.06±3.23 µg GAE/100 mL for Balanites aegyptiaca while the antioxidant activity is ranged between 31.76±2.35 and 58.47±4.24 µg AEAC/100 mL for Carica papaya and from 29.80±0.32 to 78.44±2.81 µg AEAC/100 mL for Balanites aegyptiaca. Infusion’s extracts always have the highest values of polyphenols content and antioxidant activity than decoction extracts, be it papaya or balanites seeds. Neitheir flavonoids content nor antibacterial activity was found. The inhibition diameter varies from 14.5±0.5 to 40.5±0.5 mm for papaya seeds extracts and from 16.5±0.5 to 21.0±0.5 mm for balanites seeds extracts without a significative effect of mixture for both extracts. MICs vary from 11.71±0.1 to 75.0±0.0 mg. mL-1 for Carica papaya seeds extracts with 11.72±0.2 to 37.30±0.2 mg. mL-1 and 18.74±0.1 to 100±0.0 mg.mL-1 for Balanites aegyptiaca. Mixture extracts presented intermediaire values. Decoction extracts have lowest MICs values and infusion reveals itself to be the sweetable aqueous extraction techniques but the appropriate infusion time need to be highlight.

Keywords: Carica papaya, Balanites aegyptiaca, Seeds extracts, Phytochemical, antifungal

Keywords:

Carica papaya, Balanites aegyptiaca, Seeds extracts, Phytochemical, antifungal

DOI

https://doi.org/10.22270/jddt.v14i2.6393

Author Biographies

Assétou OUEDRAOGO, Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso

Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Philippe Augustin NIKIEMA, Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso

Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso

Marguerite Edith Malatala NIKIEMA, Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso

Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso

Josias Gérard YAMEOGO, Laboratoire du Développement du Médicament (LADME), Centre de Formation de Recherche et d’Expertises en Sciences du Médicament (CEA-CFOREM), Université Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso

Laboratoire du Développement du Médicament (LADME), Centre de Formation de Recherche et d’Expertises en Sciences du Médicament (CEA-CFOREM), Université Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso

Bernadette Pane SOURABIE, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Belinda Ramata Hafouo BASSAVE, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Oueogo NIKIEMA, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Florent Wendinmi Bertrand GOUMBRI, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des produits de santé (ANSSEAT)

Nicolas BARRO, Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso

Laboratoire de Biologie moléculaire, d’Epidémiologie et de Surveillance des bactéries et virus Transmissibles par les Aliments (LaBESTA), Université Joseph KI-ZERBO, Ouagadougou 03, Burkina Faso

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Published

15-02-2024
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How to Cite

1.
OUEDRAOGO A, NIKIEMA PA, NIKIEMA MEM, YAMEOGO JG, SOURABIE BP, BASSAVE BRH, et al. Phytochemicals properties and antimicrobial activities of Carica papaya and Balanites aegyptiaca’ seeds aqueous infusion and decoction extracts. J. Drug Delivery Ther. [Internet]. 2024 Feb. 15 [cited 2025 Feb. 19];14(2):46-52. Available from: https://jddtonline.info/index.php/jddt/article/view/6393

How to Cite

1.
OUEDRAOGO A, NIKIEMA PA, NIKIEMA MEM, YAMEOGO JG, SOURABIE BP, BASSAVE BRH, et al. Phytochemicals properties and antimicrobial activities of Carica papaya and Balanites aegyptiaca’ seeds aqueous infusion and decoction extracts. J. Drug Delivery Ther. [Internet]. 2024 Feb. 15 [cited 2025 Feb. 19];14(2):46-52. Available from: https://jddtonline.info/index.php/jddt/article/view/6393

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