A Comparative Study on Caprini RAM Vs DOH Tool for Thromboprophylaxis in ICU Setting at Tertiary Care Hospital

  • G HARINE PHARM D, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India
  • K. Bharathi Priya Associate professor, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India https://orcid.org/0000-0002-5022-6636
  • A Pavithra PHARM D, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India
  • Devachandran Jayakumar ICU Intensivist, Dr.Kamakshi Memorial hospital, Chennai, India https://orcid.org/0000-0001-7134-3746
  • Mohammed Farazuddin Clinical Pharmacist, Dr.Kamakshi Memorial hospital, Chennai, India
  • Satya Tejaswini Clinical Pharmacist, Dr.Kamakshi Memorial hospital, Chennai, India

Abstract

The aim of the study was to assess DVT prophylaxis using two models (Caprini RAM & DOH tool) for the prevention of DVT in postoperative or critically ill patients and for better predictability of disease. In this prospective observational study, we compared the Caprini RAM and DOH tool in the ICU setting on 229 patients (140 men and 89 women). 205 patients were considered in the study, out of which 97 had Caprini RAM and 108 had DOH tool. A Prospective, observational comparative study was carried out in a tertiary care hospital for a period of 6 months. Patients were divided into two groups according to the RAM. The data were analyzed using SPSS software and the results were compared using the student t-test. Both GROUP A and GROUP B revealed that the majority of the patients (67.1% & 55.6%) were above 60 years and a large proportion of them required DVT prophylaxis. In GROUP A 93% of forms were complete with 79% accuracy. In GROUP B 83% were complete. The most appropriate prophylaxis received by patients was Enoxaparin sodium 40 mg OD for about 97 (30%) patients and Heparin 5000 IU BD for 108 (30%) based on their Caprini scores and NICE guidelines respectively. The majority of patients in Group A did not require dosage adjustments, but in 20% of cases, it was necessary. Statistical significance was achieved with a p-value less than 0.05. The study demonstrates DOH tool is better than Caprini RAM to be used in hospitals, for risk assessment of VTE in both medical and surgical patients for accuracy and predictability of the prophylaxis.


Keywords: DVT, Risk assessment, Caprini RAM, DOH tool, pharmacological and mechanical Prophylaxis.

Keywords: DVT, Risk assessment, Caprini RAM, DOH tool, pharmacological and mechanical Prophylaxis

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Author Biographies

G HARINE, PHARM D, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India

PHARM D, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India

K. Bharathi Priya, Associate professor, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India

Associate professor, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India

A Pavithra, PHARM D, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India

PHARM D, C.L. Baid Metha College of Pharmacy, The Tamil Nadu Dr. MGR Medical University, Chennai, Tamil Nadu, India

Devachandran Jayakumar, ICU Intensivist, Dr.Kamakshi Memorial hospital, Chennai, India

ICU Intensivist, Dr.Kamakshi Memorial hospital, Chennai, India

Mohammed Farazuddin, Clinical Pharmacist, Dr.Kamakshi Memorial hospital, Chennai, India

Clinical Pharmacist, Dr.Kamakshi Memorial hospital, Chennai, India

Satya Tejaswini, Clinical Pharmacist, Dr.Kamakshi Memorial hospital, Chennai, India

Clinical Pharmacist, Dr.Kamakshi Memorial hospital, Chennai, India

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HARINE G, Bharathi Priya K, Pavithra A, Jayakumar D, Farazuddin M, Tejaswini S. A Comparative Study on Caprini RAM Vs DOH Tool for Thromboprophylaxis in ICU Setting at Tertiary Care Hospital. JDDT [Internet]. 15Sep.2023 [cited 2Oct.2023];13(9):55-1. Available from: https://jddtonline.info/index.php/jddt/article/view/6198