A Comprehensive Scientific Claims on Ethnobotany, Phytochemical Pharmacological and Toxicology of Withania somnifera (L.) Dunal

An updated ethnobotany, phytochemical and pharmacological potential of Withania somnifera

Authors

Abstract

For more than 3,000 years, Withania somnifera, commonly known as Ashwagandha, has been utilised in traditional and Ayurvedic medicine. It belongs to the ginger family. Dry powder, crude extract, and refined metabolites of the plant have all demonstrated potential therapeutic advantages in animal trials because it is a medicinal plant. Withanolides are the primary metabolites of the plant, and they are responsible for the therapeutic effects of the herb. Despite the fact that other review papers on this plant have previously been published, this review article is being provided in order to gather all of based on the most recent data on its pharmacological and phytochemical effects, which have been investigated using a variety of approaches. According to research, Ashwagandha has anti-inflammatory, adaptogen, anti-parkinsonian, anti-oxidant, and memory-boosting properties, and anticancer effects in addition to other benefits. Other effects, such as immunomodulation, hypolipidemia, antimicrobial activity, Investigations have also been done on cardiovascular defence, sexual behaviour, tolerance, and reliance. These outcomes are extremely encouraging, and they recommend more research into this herb to confirm these results and find further potential medicinal characteristics. Clinical studies including the use of ashwagandha for a number of illnesses should be carried out as well. The new evidence on its pharmacological and phytochemical activities is described in the current publication. In order to give thorough information on the ethnobotany, traditional applications, phytochemistry, and pharmacological efficacy of the medicinal plant, W. somnifera, from reliable sources, the present review has primary objectives.

Keywords:  Withania somnifera, Solanaceae, traditional claim, ethnobotany, phytochemistry, phytopharmacology

Keywords:

Withania somnifera, Solanaceae, traditional claim, ethnobotany, phytochemistry, phytopharmacology

DOI

https://doi.org/10.22270/jddt.v13i3.6003

Author Biographies

Md Sarfaraj Hussain, Lord Buddha Koshi College of Pharmacy, Baijanathpur, Saharsa, 852201, Bihar, India

Lord Buddha Koshi College of Pharmacy, Baijanathpur, Saharsa, 852201, Bihar, India

SS Alqahtani, Department of Pharmacy Practice, College of Pharmacy, Jizan University, Jizan, Kingdom of Saudi Arabia.

Department of Pharmacy Practice, College of Pharmacy, Jizan University, Jizan, Kingdom of Saudi Arabia

Sarfaraz Ahmad, Department of Pharmacy Practice, College of Pharmacy, Jizan University, Jizan, Kingdom of Saudi Arabia

Department of Pharmacy Practice, College of Pharmacy, Jizan University, Jizan, Kingdom of Saudi Arabia

Mohd Rashid Iqbal, Department of Pharmacognosy & Phytochemistry, School of Pharmacy, Glocal University, Delhi Yamunotri Marg, Mirzapur Pole District- Saharanpur, U.P. India. 247121

Department of Pharmacognosy & Phytochemistry, School of Pharmacy, Glocal  University, Delhi Yamunotri Marg, Mirzapur Pole District- Saharanpur, U.P. India. 247121

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How to Cite

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Hussain MS, Alqahtani S, Ahmad S, Iqbal MR. A Comprehensive Scientific Claims on Ethnobotany, Phytochemical Pharmacological and Toxicology of Withania somnifera (L.) Dunal: An updated ethnobotany, phytochemical and pharmacological potential of Withania somnifera. J. Drug Delivery Ther. [Internet]. 2023 Mar. 15 [cited 2025 Feb. 18];13(3):194-207. Available from: https://jddtonline.info/index.php/jddt/article/view/6003

How to Cite

1.
Hussain MS, Alqahtani S, Ahmad S, Iqbal MR. A Comprehensive Scientific Claims on Ethnobotany, Phytochemical Pharmacological and Toxicology of Withania somnifera (L.) Dunal: An updated ethnobotany, phytochemical and pharmacological potential of Withania somnifera. J. Drug Delivery Ther. [Internet]. 2023 Mar. 15 [cited 2025 Feb. 18];13(3):194-207. Available from: https://jddtonline.info/index.php/jddt/article/view/6003