Assessment of rheumatoid arthritis and associated risk factors among patients attending Kibungo level two teaching hospital

Authors

  • Pierre Celestin Munezero School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.
  • Pacifique Mukiza Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.
  • Jean Berchmas Mutijima Department of Pathology Laboratory, Legacy Clinics, Kigali, Rwanda.
  • Janviere Kankindi Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.
  • Alexis Nshimiyimana Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.
  • Alain Prudence Ishimwe Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.
  • Jean de Dieu Tuyishime Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.
  • Jean Paul Sinumvayo School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.
  • Francois Xavier Ndayambaje School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.
  • Joseph Ndacyayisenga Department of Molecular Biology and Biotechnology, Pan African University-Institute for Basic Sciences, Technology and Innovation (PAUSTI), Nairobi, Kenya.

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints, but can affect other parts of the body causing inflammation, pain, stiffness, and joint damage. It affects approximately 1% of the global population. The objectives of this study were to assess the prevalence of rheumatoid arthritis and risk factors associated with rheumatoid arthritis among patients attending Kibungo level two teaching hospital. The retrospective study extracted data from January, 2018 to January 2023 and the cross-sectional part assessed risk factors associated to rheumatoid arthritis using questionnaire by telephone calls. Data collected were analyzed statistically using SPSS version 25. In this study the prevalence of rheumatoid arthritis was 43.20%. Across sex, females were more affected than males (44.2% and 40.0%, respectively). Binary logistic regression was used to assess the association between RA and risk factors. Age groups, C-Reactive Protein, red meat consumption showed significant association with RA (OR = 1.566, p = 0.008; OR = 1.299, p = 0.013; OR = 2.599, p < 0.001). The study was limited since it only included the participants at Kibungo Level two Teaching hospital, hence not having large population. Carrying out country wide studies regarding to the rheumatoid arthritis and associated risk factors on large population in order to establish epidemiologic data in Rwanda is  highly recommended.

Keywords: Rheumatoid arthritis, risk factors, C-Reactive Protein, Rheumatoid Factor

Keywords:

Rheumatoid arthritis, risk factors, C-Reactive Protein, Rheumatoid Factor

DOI

https://doi.org/10.22270/jddt.v13i9.5962

Author Biographies

Pierre Celestin Munezero, School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.

School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.

Pacifique Mukiza, Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Jean Berchmas Mutijima, Department of Pathology Laboratory, Legacy Clinics, Kigali, Rwanda.

Department of Pathology Laboratory, Legacy Clinics, Kigali, Rwanda.

Janviere Kankindi, Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Alexis Nshimiyimana, Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Alain Prudence Ishimwe, Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Jean de Dieu Tuyishime, Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

Jean Paul Sinumvayo, School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.

School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.

Francois Xavier Ndayambaje, School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.

School of Medicine and Pharmacy, University of Rwanda, Kigali, Rwanda.

Joseph Ndacyayisenga, Department of Molecular Biology and Biotechnology, Pan African University-Institute for Basic Sciences, Technology and Innovation (PAUSTI), Nairobi, Kenya.

Department of Biotechnology, INES Ruhengeri-Institute of Applied Sciences, Musanze, Rwanda.

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Published

2023-09-15
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How to Cite

1.
Munezero PC, Mukiza P, Mutijima JB, Kankindi J, Nshimiyimana A, Ishimwe AP, et al. Assessment of rheumatoid arthritis and associated risk factors among patients attending Kibungo level two teaching hospital. J. Drug Delivery Ther. [Internet]. 2023 Sep. 15 [cited 2026 Jan. 21];13(9):119-24. Available from: https://jddtonline.info/index.php/jddt/article/view/5962

How to Cite

1.
Munezero PC, Mukiza P, Mutijima JB, Kankindi J, Nshimiyimana A, Ishimwe AP, et al. Assessment of rheumatoid arthritis and associated risk factors among patients attending Kibungo level two teaching hospital. J. Drug Delivery Ther. [Internet]. 2023 Sep. 15 [cited 2026 Jan. 21];13(9):119-24. Available from: https://jddtonline.info/index.php/jddt/article/view/5962

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