A Comprehensive Review on Edible Vaccine

  • Vrunda Vipul Shah Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India
  • Riddhi Ashokbhai Prajapati National Forensic Sciences University, Gandhinagar, Gujarat, India
  • Saloni Pratikbhai Shah Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India
  • Shiv Rakeshbhai Patel Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India
  • Harshil Pankajkumar Patel Synzeal research Pvt Ltd, Ahmedabad, Gujarat, India

Abstract

A New approach for vaccine delivery Antigen is the use of inexpensive of oral vaccines. Is ideal for edible vaccination since it grows quickly and has a lot of nutrients that improve the immune system. Edible oral vaccines supply exciting Prospects for considerably reducing the burden of disease like hepatitis and diarrhea Significantly within the developing world wherever storing and Administering vaccines are typically major problem. They have several benefits as they trigger the Immunity at the tissue layer surface which is the body’s first line of defense. Painful vaccination processes are replaced by an edible vaccine. In comparison to traditional vaccines, edible vaccines are needle-free, low-cost, do not require refrigeration, may be stored close to the point of application, are safe, and give mucosal and systemic protection. Vaccines play a vital role in the prevention and treatment of a wide range of diseases. The Review's major goal is to provide comprehensive information on edible vaccines. The main aim of the Review is to provide an all over information related to edible vaccine. The hope is the edible vaccine could be grown in the developing Many of countries Where their need is more.


Keywords: edible vaccine, fruits, immunity, vaccination, transgene, antigen

Keywords: edible vaccine, fruits, immunity, vaccination, transgene, antigen

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Author Biographies

Vrunda Vipul Shah, Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India

Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India

Riddhi Ashokbhai Prajapati, National Forensic Sciences University, Gandhinagar, Gujarat, India

National Forensic Sciences University, Gandhinagar, Gujarat, India

Saloni Pratikbhai Shah, Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India

Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India

Shiv Rakeshbhai Patel, Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India

Arihant School of Pharmacy and Bioresearch Institute, Adalaj, Gandhinagar, Gujarat, India

Harshil Pankajkumar Patel, Synzeal research Pvt Ltd, Ahmedabad, Gujarat, India

Synzeal research Pvt Ltd, Ahmedabad, Gujarat, India

References

[1] Esmael H, "Review on Edible Vaccine, Acad. J. Nutri", 2015; 4(1):40-49.
[2] Sri R, journal of medicine. volume 1 issue 1 September 2006.
[3] Goyal R, Sharma R, Lal P, Ramachandran V, "Edible vaccines: Current status and future. Indian Journal of Medical Microbiology", 2007; 25-93. https://doi.org/10.4103/0255-0857.32713
[4] Langridge WH, "Edible vaccines. Scientific American", 2000; 283:66-71. https://doi.org/10.1038/scientificamerican0900-66
[5] Arakawa T, Chong DK, Langridge WH, "Efficacy of a food Plant-based oral cholera toxin B subunit vaccine. Nat Biotechnology, 1998; 16(3):292-7. https://doi.org/10.1038/nbt0398-292
[6] WHO. The 10 leading causes of death in the world, 2000 and 2012. WHO Media centre. 2016.
[7] Hilleman MR, "Vaccines in historic evolution and perspective: A narrative of vaccine discoveries" Vaccine , 2000; 18:1436-47. https://doi.org/10.1016/S0264-410X(99)00434-X
[8] Hilleman MR, "Overview of the needs and realities for developing new and improve vaccines in the 21st century" Intervirology, 2002; 45:199-211. https://doi.org/10.1159/000067911
[9] Mäkelä PH, "Vaccines, coming of age after 200 years" FEMS Microbiol Rev, 2000; 24:9-20. https://doi.org/10.1016/S0168-6445(99)00025-X
[10] Yusibov V, Rabindran S, "Recent progress in the development of plant derived vaccines" Expertise Rev Vaccines, 2008; 7:1173-83. https://doi.org/10.1586/14760584.7.8.1173
[11] Barta A, Sommergruber K, Thompson D, Hartmuth K, Matzke M, A, Matzke A, J, "The expression of a nopaline synthase - human growth hormone chimaeric gene in transformed tobacco and sunflower callus tissue" Plant. Mol. Biol, 1986; 6(5):347-357. https://doi.org/10.1007/BF00034942
[12] Glick B.R, Pasternak J.J, Patten Ch.L Molecular Biotechnology,Principles and Applications of Recombinant DNA, 4th ed.ASM Press: Herndon, VA, USA:2010, p. 999.
[13] Organización Mundial de la Salud (OMS); United Nations Children's Fund (UNICEF); BancoMundial. Vacunas e Inmunización: Situación Mundial, 3rd ed. Organización Mundial de la Salud: Ginebra, Suiza: 2010.
[14] Kumru O, Joshi S, Smith D, Russell C, Prusik T, Volkin D," Vaccine instability in the cold chain:Mechanisms, analysis and formulation strategies" Biologicals, 2014; 42: 237-249. https://doi.org/10.1016/j.biologicals.2014.05.007
[15] Daniell H, Streatfield S.J, Wyckoff K, "Medical molecular farming: Production of antibiotics, biopharmaceuticals and edible vaccines in plants" Trends Plant Sci, 2001; 6:219-226. https://doi.org/10.1016/S1360-1385(01)01922-7
[16] Mason H.S, Haq T.A, Clements J.D, "Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT), Potatoes expressing a synthetic LT-B gene" Vaccine ,1998; 16:1336-1343 https://doi.org/10.1016/S0264-410X(98)80020-0
[17] Concha C, Canas R, Mucuer J, Torres M, Herrada A, Jamett F, Ibanez C,"Disease Prevention: An Opportunity to Expand Edible Plant-Based Vaccines" Vaccine ,2017; 5(2):14. https://doi.org/10.3390/vaccines5020014
[18] Dalsgaard K, Uttenthal A, Jones T.D, Xu F, Merryweather A, Hamilton W.D, Langeveld J.P, Boshuizen R.S, Kamstrup S, Lomonossoff G.P, et al,"Plant-derived vaccine protects target animals against a viral disease"Nat. Biotechnol,1997;15:248-252. https://doi.org/10.1038/nbt0397-248
[19] Castañon S, Marín M.S, Martín-Alonso J.M, Boga J.A, Casais R, Humara J.M, Ordás R.J, Parra F,"Immunization with potato plants expressing VP60 protein protects against rabbit hemorrhagic disease virus" J. Virol, 1999; 73:4452-4455. https://doi.org/10.1128/JVI.73.5.4452-4455.1999
[20] Hahn B.S, Jeon I.S, Jung Y.J, Kim J.B, Park J.S, Ha S.H, Kim K.H, Kim H.M, Yang J.S,Kim Y.H,"Expression of hemagglutinin-neuraminidase protein of Newcastle disease virus in transgenic tobacco"PlantBiotechnol. Rep, 2007; 1: 85-92. https://doi.org/10.1007/s11816-007-0012-9
[21] Mason H.S, Ball J.M, Shi J.J, Jiang X, Estes M.K, Arntzen C.J," Expression of Norwlak virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice" Proc. Natl. Acad. Sci. USA, 1996; 93:5335-5340. https://doi.org/10.1073/pnas.93.11.5335
[22] Lacorte C, Lohuis H, Goldbach R, Prins M," Assessing the expression of chicken anemia virus proteins in plants"Virus Res, 2007; 129:80-86. https://doi.org/10.1016/j.virusres.2007.06.020
[23] Kostrzak A, Cervantes M, Guetard D, Nagaraju D.B, Wain-Hobson S, Tepfer D, Pniewski T, Sala M,"Oral administration of low doses of plant-based HBsAg induced antigen-specific IgAs and IgGs in mice, without increasing levels of regulatory T cells" Vaccine, 2009; 27:4798-4807. https://doi.org/10.1016/j.vaccine.2009.05.092
[24] Gómez E, Zoth S.C, Asurmendi S, Rovere C.V, Berinstein A,"Expression of HemagglutininNeuraminidase glycoprotein of Newcastle Disease Virus in agroinfiltratedNicotianabenthamiana.PlantsBiotechnol. J" 2009; 144:337-340. https://doi.org/10.1016/j.jbiotec.2009.09.015
[25] Kanagarajan S, Tolf C, Lundgren A, Waldenstrom J, Brodelius P.E," Transient Expression of Hemagglutinin Antigen from Low Pathogenic Avian Influenza A (H7N7) in Nicotianabenthamiana" PLoS ONE ,2012; 7:e33010. https://doi.org/10.1371/journal.pone.0033010
[26] Shoji Y, Farrance C.E, Bautista J, Bi H,Musiychuk K, Horsey A, Park H, Jaje J, Green B.J, Shamloul M, et al," A plant-based system for rapid production of influenza vaccine antigens. Influ. Other Respir Viruses: 2012; 6:204-210. https://doi.org/10.1111/j.1750-2659.2011.00295.x
[27] Gorantala J, Grover G, Rahi A, Chaudhary P, Rajwanshi R, Sarin L.B, Bhatnagar," Generation of protective immune response against anthrax by oralimmunization with protective antigen plant-based vaccine. J. Biotechnol" 2014; 176:1-10. https://doi.org/10.1016/j.jbiotec.2014.01.033
[28] Zhang X, Buehner N, Hutson A, Estes M, Manson H," Tomato is a highly effective vehicle for expresión and oral immunization with Norwalk virus capsid protein." Plant Biotechnol. J, 2006; 4:419-432. https://doi.org/10.1111/j.1467-7652.2006.00191.x
[29] Lou X.M ,Yao Q.H, Zhang Z, Peng R.H, Xiong A.S, Wang H.K," Expression of the human hepatitis B virus large surface antigen gene in transgenic tomato plants" Clin. Vaccine Immunol, 2007; 14:464-469. https://doi.org/10.1128/CVI.00321-06
[30] Srinivas L, Kumar G, Ganapathi T.R, Revathi C.J, Bapat V.A, " Transient and stable expression of hepatitis b surface antigen in tomato (Lycopersiconesculentum)" Plant Biotechnol. Rep, 2008; 2:1-6. https://doi.org/10.1007/s11816-008-0041-z
[31] Youm J.W, Jeon J.H, Kim H, Kim Y.H, Ko K, Joung H, Kim H,"Transgenic tomatosexpressinghuman beta-amyloid for use as a vaccine against Alzheimer's disease"Biotechnol. Lett, 2008; 30:1839-1845. https://doi.org/10.1007/s10529-008-9759-5
[32] Kim T.G, Kim M.Y, Kim B.G, Kang T.J, Kim Y.S, Jang Y.S, Arntzen C.J, Yang M.S," Syntesis and assembly of Escherichia coli heat-labile enterotoxin B subunit in transgenic lettuce (Lactuca sativa)" Protein Expr. Purif, 2007; 51:22-27. https://doi.org/10.1016/j.pep.2006.05.024
[33]"A Molecular farming on the rise-GMO regulators still walking a tightrope" Trends Biotechnol. 2007; 25:74-82.34. https://doi.org/10.1016/j.tibtech.2006.12.003
[34] Oszvald M, Kang T.J, Tomoskozi S, Tamas C, Tamas L, Kim T.G, Yang M.S,"Expression of a synthetic neutralizing epitope of porcine epidemic diarrhea virus fused with synthetic b subunit of Escherichia coli heat labile enterotoxin in rice endosperm" Mol. Biotechnol, 2007; 35:215-223. https://doi.org/10.1007/BF02686007
[35] Qian B.J, Shen H.F, Liang W.Q, Guo X.M, Zhang C, Wang Y, Li G, Wu A, Cao K, Zhang D, "Immunogenicity of recombinant hepatitis b virus surface antigen fused with pres1 epitopes expressed in rice seeds" Transgenic Res, 2008; 17:621-631. https://doi.org/10.1007/s11248-007-9135-6
[36] Oszvald M, Kang T.J, Tomoskozi S, Jenes, B, Kim T.G, Cha Y.S, Tamas L, Yang M.S, "Expression of cholera toxin B subunit in transgenic rice endosperm" Mol. Biotechnol, 2008; 40:261-268. https://doi.org/10.1007/s12033-008-9083-2
[37] USDA. Rice World Markets and Trade. Foreign Agricultural Service/USDA. Office of GlobalAnalysis.January2017.Available online:https://apps.fas.usda.gov/psdonline/circulars/grain rice.pdf (accessed on5 May 2017).Vaccines 2017; 5(14):22 of 23
[38] Rosales-Mendoza S, Alpuche-Solís A, Soria-Guerra R, Moreno-Fierros L, Martínez-González L,Herrera-Díaz A, Korban S.S," Expression of an Escherichia coli antigenic fusion protein comprising the heat labile toxin B subunit and the heat stable toxin and its assembly as a functional oligomer in transplastomicbtobacco plants" Plant J, 2008; 57:45-54. https://doi.org/10.1111/j.1365-313X.2008.03666.x
[39] Zhang H, Liu M, Li Y, Zhao Y, He H, Yang G, Zheng C," Oral immunogenicity and protective efficacy in mice of a carrot-derived vaccine candidate expressing UreB subunit against Helicobacter pylori" Protein Expr.Purif, 2010; 69:127-131. https://doi.org/10.1016/j.pep.2009.07.016
[40] Ekam V.S, Udosen E.O, Chighu A.E, "Comparative Effect of Carotenoid Complex from Goldenneo-Life Dynamite and Carrot Extracted Carotenoids on Immune Parameters in Albino Wistar Rats" Niger. J.Physiol. Sci, 2006; 21:1-4. https://doi.org/10.4314/gjpas.v12i4.16648
[41] Wigdorovitz A, Pérez Filgueira D.M, Robertson N, Carrillo C, Sadir A.M, Morris T.J, Borca M.V,"Protection of mice against challenge with foot and mouth disease virus (FMDV) by immunization with foliar xtracts from plants infected with recombinant tobacco mosaic expressing the FMDV structural protein VP1" Virology, 1999; 264:85-91. https://doi.org/10.1006/viro.1999.9923
[42] Wigdorovitz A, Mozovoj M, Santos M, Parreno V, Gomez C, Perez-Filgueira D.M, Trono, K.G.;Ríos R.D, Franzone P.M, Fernández F,et al," Protective lactogenic immunity conferred by an edible peptide vaccine to bovine rotavirus produced in transgenic plants" J. Gen. Virol, 2004; 85:1825-1832. https://doi.org/10.1099/vir.0.19659-0
[43] Huang L.K., Liao S.C, Chang C.C, Liu H.J, "Expression of avian reovirusσC protein in transgenic plants.J. Virol." Methods, 2006; 134:217-222. https://doi.org/10.1016/j.jviromet.2006.01.013
[44] Yan-Ju Y.E, Wen-Gui, L.I," Immunoprotection of transgenic alfalfa (Medicago sativa) containing Eg95-EgA31 fusion gene of Echinococcusgranulosus against Egprotoscoleces" J. Trop. Med, 2010; 3:10-13.
[45] Guerrero-Andrade O, Loza-Rubio E, Olivera-Flores T, Fehérvári-Bone T, Gómez-Lim M.A, " Expression of the Newcastle disease virus fusion protein in transgenic maize and immunological studies" Transgenic Res,2006; 15:455-463. https://doi.org/10.1007/s11248-006-0017-0
[46] Chen, T.H.; Chen, T.H.; Hu, C.C.; Liao, J.T.; Lee, C.W.; Liao, J.W.; Lin, M.Y.; Liu, H.J.; Wang, M.Y.;Lin, N.S.; et al. Induction of protective immunity in chickens immunized with plant-made chimeric Bamboo mosaic virus particles expressing very virulent Infectious bursal disease virus antigen. Virus Res. 2012; 166:109-115. https://doi.org/10.1016/j.virusres.2012.02.021
[47] Kumar G.B.S, Ganapathi T.R, Revathi C.J, Srinivas L, Bapat V.A, "Expression of hepatitis B surface antigen in transgenic banana plants"Planta, 2005; 222:484-493. https://doi.org/10.1007/s00425-005-1556-y
[48] Guan Z.-J, Guo B, Huo, Y.L, Guan, Z.-P, Wei Y.-H," Overview of expression of hepatitis B surface antigen in transgenic plants"Vaccine ,2010; 28:7351-7362. https://doi.org/10.1016/j.vaccine.2010.08.100
[49] Satyavathi V.V, Prasad V, Khandelwal A, Shaila M.S, Sita G.L," Expression of hemagglutinin protein of Rinderpest virus in transgenic pigeon pea [Cajanuscajan (L.) Millsp.] plants," Plant Cell Rep, 2003; 21:651-658. https://doi.org/10.1007/s00299-002-0540-2
[50] Lau J.M, Korban S.S, " Transgenic apple expressing an antigenic protein of the human respiratory synsytial virus" J. Plant Physiol,2010; 167:920-927. https://doi.org/10.1016/j.jplph.2010.02.003
[51] Gao Y, Ma Y, Li M, Cheng T,Li S.-W, Zhang J, Xia N.-S," Oral immunization of animals with transgenic cherry tomatillo expressing HBsAg" World J. Gastroenterol, 2003; 9:996-1002. https://doi.org/10.3748/wjg.v9.i5.996
[52] Tran M, Zhou B, Pettersson P.L, Gonzalez M.J, Mayfield S.P, "Synthesis and assembly of a full-length human monoclonal antibody in algal chloroplasts"Biotechnol. Bioeng, 2009; 104:663-673. https://doi.org/10.1002/bit.22446
[53] Yan N, Fan C, Chen Y, Hu Z, "The Potential for Microalgae as Bioreactors to Produce Pharmaceuticals" Int. J. Mol. Sci, 2016; 17:962. https://doi.org/10.3390/ijms17060962
[54] Franconi R, Demurtas O.C, Massa S, "Plant-derived vaccines and other therapeutics produced in contained systems" Expert Rev. Vaccines, 2010; 9:877-892. https://doi.org/10.1586/erv.10.91
[55] Dreesen I.A, Charpin-El H.G, Fussenegger M, "Heat-stable oral alga-based vaccine protects mice from Staphylococcus aureus infection, J. Biotechnol, 2010;145:273-280. https://doi.org/10.1016/j.jbiotec.2009.12.006
[56] Gregory J.A, Topol A.B, Doerner D.Z, Mayfield S, "Alga-produced cholera toxin-pfs25 fusion proteins as oral vaccines" Appl. Environ. Microbiol, 2013; 79 3917-3925. https://doi.org/10.1128/AEM.00714-13
[57] Franklin S.E, Mayfield S.P,"Recent developments in the production of humaneukaryotic algae"Expert Opin. Biol. Ther, 2005; 5: 225-235. https://doi.org/10.1517/14712598.5.2.225
[58] "Current Drug Metabolism" 2017; 18:No.00.
[59] Richman LK, et al, "Enterically induced immunologic tolerance. I. Induction of suppressor T lymphoyctes by intragastric administration of soluble proteins" The Journal of Immunology, 1978; 121:2429-2434. [60] Kesik-Brodacka,M., et al," Immune response of rats vaccinated orally with various plant-expressed recombinant cysteine proteinase constructs when challenged with Fasciola hepatica metacercariae" PLoS Neglected Tropical Diseases, 2017; 2017:11. https://doi.org/10.1371/journal.pntd.0005451
[61] Clarke JL, et al, "Lettuce-produced hepatitis C virus E1E2 heterodimer triggers immune responses in mice and antibody production after oral vaccination" Plant Biotechnology Journal, 2017; 15(12):1611-1621. https://doi.org/10.1111/pbi.12743
[62] Singh BD, "Biotechnology. New Delhi: Kalyani Publishers", 1998.
[63] Madhumita N, et al, "Edible vaccines-A review. International Journal of Pharmacotherapy" 2014; 4:58.
[64] Fauquet C, et al. "Particle bombardment and the genetic enhancement of crops: Myths and realities" Molecular Breeding, 2005; 15(3):305-327. https://doi.org/10.1007/s11032-004-8001-y
[65] Ma H, Chen G, "Gene transfer technique. Nature and Science" 2005; 3(1):25-31.
[66] Chen Q, Lai H, " Gene delivery into plant cells for recombinant protein production" BioMed Research International, 2015; doi: 10.1155/2015/932161. https://doi.org/10.1155/2015/932161
[67] Gomez E, "Developments in plant-based vaccines against diseases of concern in developing countries" The Open Infectious Diseases Journal, 2010; 4(2):55-62. https://doi.org/10.2174/1874279301004010055
[68] Kim T, Yang M, "Current trends in edible vaccine development using transgenic plants" Biotechnology abd Bioprocess Engineering, 2010; 15(1):61-65. https://doi.org/10.1007/s12257-009-3084-2
[69] Shah CP, et al, " Edible vaccine: A better way for immunisation. International Journal of Current Pharmaceutical Research" 2011; 3(1):1-4.
[70] Vasil K, Vasil V, et al, "Transformation of wheat via particle bombardment" Plant Cell, 1965; 111:9.
[71] Santi L, " Plant derived veterinary vaccines. Veterinary Research Communications" 2009; 33(1):61-66. https://doi.org/10.1007/s11259-009-9246-z
[72] Arakawa T, et al, "Expression of cholera toxin B subunit oligomers in transgenic potato plants" Transgenic Research, 1997; 6(6): 403-413. https://doi.org/10.1023/A:1018487401810
[73] Wu L, et al, "Expression of foot-and-mouth disease virus epitopes in tobacco by a tobacco mosaic virus-based vector"Vaccine, 2003; 21(27-30): 4390-4398. https://doi.org/10.1016/S0264-410X(03)00428-6
[74] Arakawa T,et al, " Transgenic plants for the production of edible vaccine and antibodies for immunotherapy" Nature Biotechnology,1998;16: 292-297. https://doi.org/10.1038/nbt0398-292
[75] William S, "A review of the progression of transgenic plants used to produce plant bodies for human usage" Journal of Young Investigators, 2002:4(2002):56-61.
[76] Renuga G, et al, "Transgenic banana callus derived recombinant cholera toxin B subunit as potential vaccine" International Journal of Current Science, 2014; 10:61-68.
[77] Yu J, Langridge WH, et al, "Novel approaches to oral vaccines: Delivery of antigens by edible plants" Current Infectious Disease Reports, 2000; 2:73-77. https://doi.org/10.1007/s11908-000-0091-z
[78] Guan ZJ,et al" Recent advances and safety issues of transgenic plant-derived vaccines" Applied Microbiology and Biotechnology, 2013; 97(7):2817-2840. https://doi.org/10.1007/s00253-012-4566-2
[79] Fujiki M,et al, " Development of a new cucumber mosaic virus-based plant expression vector with truncated 3a movement protein" Virology,2008; 381(1):136-142. https://doi.org/10.1016/j.virol.2008.08.022
[80] Lavelle E. C, O'Hagan D. T, "Delivery systems and adjuvants for oral vaccines." Expert. Opin. Drug. Deliv, 2006; 3(6): 747-762. https://doi.org/10.1517/17425247.3.6.747
[81] Pascual D. W, "Vaccines are for dinner. Proc. Natl. Acad. Sci. U.S.A" 2007; 104(26):10757-10758. https://doi.org/10.1073/pnas.0704516104
[82] Streatfield S. J, " Regulatory issues for plant-made pharmaceuticals and vaccines"Expert. Rev. Vaccines, 2005; 4(4):591-601. https://doi.org/10.1586/14760584.4.4.591
[83] Charmi PS, M. N urmila, DV Vishwash, "JJ Edible vaccine: a better way for immunization" Int. J. Curr. Pharm. Res, 2011; 3(1):53-56.
[84] Glick B.R, Pasternak J.J, Patten Ch.L, "Molecular Biotechnology"Principles and Applications of Recombinant DNA, 4th ed.; ASM Press: Herndon, VA, USA, 2010.
[85] Arntzen C, Plotkin S, Dodet B, "Plant-derived vaccines and antibodies: Potential and limitations Vaccin"2005; 23:1753-1756. https://doi.org/10.1016/j.vaccine.2005.01.090
[86] Aswathi P.B, Bhanja S.K,Yadav A.S, Rekha V, John J.K, Gopinath D, Sadanandan G.V, Shinde A, Jacob A," Plant Based Edible Vaccines against Poultry Diseases: A Review. Adv. Anim"Vet. Sci, 2014; 2:305-311. https://doi.org/10.14737/journal.aavs/2014/2.5.305.311
[87] Knipe D.M, Howley P.M, Fields Virology, 6th ed, "Williams & Wilkins: Philadelphia, PA, USA" 2013; p.2456.
[88] OMS. Enfermedadporel Virus del Ebola. 2014. Available online: http://www.who.int/mediacentre/factsheets/fs103/es/ (accessed on 25 March 2015).
[89] OMS. Diphtheria Reported Cases. 2015. Available online:
http://apps.who.int/immunization_monitoring/globalsummary/timeseries/tsincidencediphtheria.htlm
(accessed on 10 July 2015).
[90] OMS. Measles-WHO European Region. 2015. Available online: http://www.who.int/csr/don/6-march-2015-measles/en/ (accessed on 10 July 2015Mishra, N.; Gupta, P.; Khatri, K.; Goyal, A.; Vyas, S. Edible vaccines: A new approach to oral immunization.Indian J. Biotechnol. 2008, 7:283-294.
[91] Waheed M.T, Sameeullah M.,Khan F.A, Syed T, Ilahi M, Gottschamenl J, Lössi A.G, " Need of cost-effective vaccines in developing countries: Whay plant biotechnology can offer? SpringerPlus "2016; 5:65. https://doi.org/10.1186/s40064-016-1713-8
[92] Alvarez M.L, Pinyerd H.L, Crisantes J.D, Rigano M.M, Pinkhasov J, Walmsley A.M, Mason H.S, Cardineau G.A, " Plant-made subunit vaccine against pneumonic and bubonic plague is orally immunogenicin mice" Vaccine 2006; 24:2477-2490. https://doi.org/10.1016/j.vaccine.2005.12.057
[93] Merlin M, Pezzotti M, Avesani L, "Edible plants for oral delivery of biopharmaceuticals" Br. J. Clin. Pharmacol. 2017, 83, 71-81.
[94] Qui, X.; Wong, G.; Audet, J.; Bello, A.; Fernando, L.; Alimonti, J.B.; Fausther-Bovendo, H.; Wei, H.; Aviles, J.;Hiatt, E.; et al. Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp. Nature 2014; 514:47-53. https://doi.org/10.1038/nature13777
[95] Organización Mundial de la Salud (OMS). Cómoenfrentarlos event ossupuestamenteatribuidos a la vacunaciónoinmunización, Vacunaciónsegura; Organización Mundial de la Salud: Washington, DC, USA, 2002. Available online: http://www.who.int/immunization_safety/publications/aefi/en/vacunacion_segura_S.pdf (accessed on 18 June 2015).
[96] Fernández A, Ortigosa S, Hervás S, Corral P, Seguí J, Gaétan J, Coursaget P,Veramendi J, "Human papillomavirus L1 protein expressed in tobacco chloroplasts self-assembles into virus-like particles that are highly immunogenic" Plant Biotechnol. J, 2008; 6:427-441 https://doi.org/10.1111/j.1467-7652.2008.00338.x
[97] Nochi T, Takagi H, Yuki Y, Yang L, Masumura T, Mejima M et al, " Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination. Proceedings of the National Academy of Sciences of the United States of America" 2007; 104:10986-10991. https://doi.org/10.1073/pnas.0703766104
[98] Streatfield S, Jilka J, Hood E,Turner D, Bailey M, Mayor J ,et al," Plant-based vaccines: unique advantages. Vaccine" 2001; 19:2742-2748. https://doi.org/10.1016/S0264-410X(00)00512-0
[99] Moss WJ, Cutts F, Griffin DE, "Implications of the human immunodeficiency virus epidemic for control and eradication of measles" Clinical Infectious Diseases, 1999; 29:106-112. https://doi.org/10.1086/520136
[100] Kay RF, Madden RH,VanSchaik C , Higdon D,(1997) "Primatespeciesrichnessis determined by plant productivity: implications for conservation" Proc Nat l Acad Sci ,94:13023-13027. https://doi.org/10.1073/pnas.94.24.13023
[101] Matoh T, Kawaguchi S, Kobayashi M, " Ubiquity of a boraterhamno galacturonan II complexing the cell walls of higher plants" Plant Cell Physio, 1996; 37:636-640. https://doi.org/10.1093/oxfordjournals.pcp.a028992
[102] Lee HL, Padmanabhan V, Whang S, "Information distortion in a supply chain: the bull whip effect" Management science, 1997; 43:546-558. https://doi.org/10.1287/mnsc.43.4.546
[103] Nakamura Y, Ito K, Isaksson LA, "Emerging understanding of translation termination Cell" 1996; 87:147-150. https://doi.org/10.1016/S0092-8674(00)81331-8
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Shah VV, Prajapati RA, Shah SP, Patel SR, Patel HP. A Comprehensive Review on Edible Vaccine. JDDT [Internet]. 15Apr.2022 [cited 17May2024];12(2-S):192-01. Available from: https://jddtonline.info/index.php/jddt/article/view/5293