Relation between low birth weight and Maternal blood lead levels in Sidi Bel Abbes, Algeria: a case-control study

Authors

  • Abbassia Demmouche Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life. Djillali Liabes University; Sidi Bel Abbes. Algeria.
  • Faiza Moussaoui Biotoxicology Laboratory, Department of Biology. Faculty of Naturel Science and life. Djillali Liabes University; Sidi Bel Abbes. Algeria

Abstract

Background: Several epidemiological studies have investigated high lead (Pb) exposure and pregnancy outcomes,but few studies have investigated the association of low lead exposure and low birth weight (LBW). The aims of this study were to estimate the maternal blood lead levels (BLL), to identify determinants for BLL among parturient woman and to evaluate the association of maternal BLL andLBW. Methods: From July 2017 to February 2018, we carried out a case control study in the genecology and obstetrics hospital of Sidi Bel Abbes, Algeria. Lead concentrations in maternal blood samples collected at delivery were measured in 29mother who delivered term LBW cases group and 29mother who give birth to a term normal weight baby matched controls.Blood lead levels were analyzed by inductively coupled plasma mass spectrometry. Results: Mean maternal BLLwere higher among normal groups than in mothers of LBW, but this difference was not significant (23,076 ±16,120, versus 18,086 ± 6,641 ug/l p=0.247).Our results indicate that the mean lead level was nothigher in LBW neonates, and the whole blood lead was not related to the birth weight. In addition,there was interaction of daily kohl use and maternal BLL. Conclusion:This study suggeststhat maternal BLL was not significantly associated with LBW. Mothers with daily use of kohl during pregnancy were more likely to have elevate blood lead concentrations.

Keywords: case-control study, low birth weight, Algeria, lead, kohl.

Keywords:

case-control study, low birth weight, lead, kohl

DOI

https://doi.org/10.22270/jddt.v10i2-s.4023

Author Biographies

Abbassia Demmouche, Biotoxicology laboratory. Department of biology. Faculty of Naturel Science and life. Djillali Liabes University; Sidi Bel Abbes. Algeria.

Biotoxicology Laboratory, Department of Biology. Faculty of Naturel Science and life.  Djillali Liabes University; Sidi Bel Abbes. Algeria

Faiza Moussaoui, Biotoxicology Laboratory, Department of Biology. Faculty of Naturel Science and life. Djillali Liabes University; Sidi Bel Abbes. Algeria

Biotoxicology Laboratory, Department of Biology. Faculty of Naturel Science and life.  Djillali Liabes University; Sidi Bel Abbes. Algeria

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Published

15-04-2020
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How to Cite

1.
Demmouche A, Moussaoui F. Relation between low birth weight and Maternal blood lead levels in Sidi Bel Abbes, Algeria: a case-control study. J. Drug Delivery Ther. [Internet]. 2020 Apr. 15 [cited 2025 Feb. 14];10(2-s):115-9. Available from: https://jddtonline.info/index.php/jddt/article/view/4023

How to Cite

1.
Demmouche A, Moussaoui F. Relation between low birth weight and Maternal blood lead levels in Sidi Bel Abbes, Algeria: a case-control study. J. Drug Delivery Ther. [Internet]. 2020 Apr. 15 [cited 2025 Feb. 14];10(2-s):115-9. Available from: https://jddtonline.info/index.php/jddt/article/view/4023

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