Evaluation of the Effect of Hydroalcoholic Extracts of Cassia Occidentalis Leaves in Neutrophil Adhesion Test in Rats

  • Dhaval M Patel SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India
  • Advaita B Patel SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India
  • Riddhi D Trivedi SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India
  • Viram J Parmar K. V. Virani Institute of Pharmacy & Research Centre, Badhda, Amreli, Gujarat, India
  • Urvisha V Bangoriya Drug Inspector, Food and Drug Administration, Gujarat, India

Abstract

Evaluation of the effect of hydroalcoholic extracts of Cassia occidentalis leaves in neutrophil adhesion test in Rats. The effect of oral administration of hydroalcoholic extract of Cassia occidentalis leaves on neutrophil has been studied and is compared with control group on rats. The differential leukocyte count (DLC) was performed by fixing the blood smears and staining with leucofine and percent neutrophils in each sample was determined. After the initial counts, blood samples were incubated with 80 mg/ml of nylon fibers for 10 min at 37ºC. Supplementation with hydroalcoholic extract of Cassia occidentalis leaves significantly decreased neutrophil adhesion. The results indicate that the leaf of Cassia occidentalis is endowed with protected neutrophil adhesion. These effects could conclude that Cassia occidentalis has an antiasthmatic property.


Keywords: Cassia occidentalis, Neutrophil adhesion, analysis of variance

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Author Biographies

Dhaval M Patel, SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India

SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India

Advaita B Patel, SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India

SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India

Riddhi D Trivedi, SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India

SAL Institute of Pharmacy, Opp-Science city, Ahmedabad-380060, Gujarat, India

Viram J Parmar, K. V. Virani Institute of Pharmacy & Research Centre, Badhda, Amreli, Gujarat, India

K. V. Virani Institute of Pharmacy & Research Centre, Badhda, Amreli, Gujarat, India

Urvisha V Bangoriya, Drug Inspector, Food and Drug Administration, Gujarat, India

Drug Inspector, Food and Drug Administration, Gujarat, India

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1.
Patel DM, Patel AB, Trivedi RD, Parmar VJ, Bangoriya UV. Evaluation of the Effect of Hydroalcoholic Extracts of Cassia Occidentalis Leaves in Neutrophil Adhesion Test in Rats. JDDT [Internet]. 28Mar.2020 [cited 17Oct.2021];9(4-s):1218-21. Available from: https://jddtonline.info/index.php/jddt/article/view/3940