Assessment of Healing Potential of Formulated Herbal Cream on Burn Wound

  • Yogesh Shivhare Sarvepalli Radhakrishnan University, Bhopal (M.P.) India
  • Alok Pal Jain Sarvepalli Radhakrishnan University, Bhopal (M.P.) India
DOI https://doi.org/10.22270/jddt.v9i4-s.3874

Abstract

The current protocol of the study was planned to assess the healing potential of formulated herbal cream containing different medicinal plant extracts. Formulated herbal cream was containing the methanolic extract of Chenopodium album, Coccinia indica, Momordica dioica, Precitrullus fistulosus and Trichosanthes dioica with cream base. Formulated herbal cream was assessed pharmacologically for healing potential in burn wound model. The formulation showed a significantly higher contraction rate, shortened epithelialization period, better tensile strength and increase in hydroxyproline content in the burn wound model. Thus, it is concluded that formulation has the potential wound healing activity which justifying its use as wound healer.


Keywords:  Formulation, Burn, Wound, Contraction

Keywords: Formulation, Burn, Wound, Contraction

Downloads

Download data is not yet available.

References

1. Anonymous. 1994. Ethnobotany in the search for new drugs. Ciba Foundation Symposium 188, John Wiley and Sons, New York.
2. Fabricant DS, Farnsworth NR. The value of plants used in traditional medicine for drug discovery. Environ Health Perspective. 2001; 109:69-75.
3. Taylor Leslie ND. Plant Based Drugs and Medicines. Rain Tree Nutrition. 2000.
4. Bhatia Nitish, Singh Arunpreet, Sharma Rohit, Singh Amandeep, Soni Varinder, Singh Gurjeet, Bajaj Jaideep, Dhawan Ravi, Singh Balwinder. Evaluation of burn wound healing potential of aqueous extract of Morus alba based cream in rats. The Journal of Phytopharmacology. 2014; 3(6):378-383.
5. Manafi A, Kohanteb J, Mehrabani D, Japoni A, Amini M, Naghmachi M, Zaghi AH, Khalili N. Active immunization using exotoxin A confers protection against Pseudomonas aeruginosa infection in a mouse burn model. BMC Microbiology. 2009; 9:23.
6. Das Trailokya, Debnath Jiban, Nath Bipul, Dash Suvakanta. Formulation and evaluation of an herbal cream for wound healing activity. International Journal of Pharmacy and Pharmaceutical Sciences. 2014; 6 (2):693-697.
7. Nair Sujith S, Mathew Molly, Sreena K. Formulation and Evaluation of Herbal Cream containing Curcuma longa. International Journal of Pharmaceutical and Chemical Sciences. 2012; 1 (4):1362-1368.
8. Kubo I, Muroi H, Kubo A. Naturally Occurring Anti-acne Agents. Journal of Natural Products. 1994; 57(1):9-17.
9. Vijayalakshmi A, Tripura A, Ravichandiran V. Development and Evaluation of Anti- Acne Products from Terminalia arjuna Bark. International Journal of Chem Tech Research. 2011; 3(1):320-327.
10. Shanmuga Priya K, Gnanamani A, Radhakrishnan N, Babu Mary. Healing potential of Datura alba on burn wounds in albino rats. Journal of Ethnopharmacology. 2002; 83:193-199.
Crossmark
Statistics
386 Views | 377 Downloads
How to Cite
1.
Shivhare Y, Jain AP. Assessment of Healing Potential of Formulated Herbal Cream on Burn Wound. JDDT [Internet]. 5Feb.2020 [cited 18Apr.2024];9(4-s):1191-4. Available from: https://jddtonline.info/index.php/jddt/article/view/3874
Issue
Vol 9 No 4-s (2019): Volume 9, Issue 4-s, July-Aug 2019 (Supplement Issue)
Section
Research
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).